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Crataegi flores (Herbal raw material) Instructions for Use

ATC Code

C01EB04 (Hawthorn glycosides)

Active Substance

Crataegi folium cum flore (DAB German Pharmacopoeia)

Clinical-Pharmacological Group

Herbal preparation used for functional disorders of the cardiovascular system

Pharmacotherapeutic Group

Cardiotonic agent of plant origin

Pharmacological Action

A herbal remedy. It has an antiarrhythmic and hypotensive effect, improves coronary and cerebral circulation, and reduces heart rate.

It lowers the excitability of the central nervous system, reduces the cholesterol content in the blood and increases the amount of lecithin; it normalizes blood clotting parameters.

In cases of hypogalactia, it increases lactation and eliminates dyspeptic phenomena in infants.

The hypotensive effect is more pronounced than that of hawthorn fruit.

Indications

Tachycardia, arterial hypertension, chronic heart failure (stages I-IIa), atherosclerosis, angina pectoris (including vasospastic angina), neurocirculatory dystonia, astheno-neurotic conditions, post-infarction cardiosclerosis, atrial tachyarrhythmia, paroxysmal supraventricular tachycardia, extrasystole, digitalis intoxication.

Insomnia, thyrotoxicosis; pneumonia, acute respiratory viral infections, cardialgia, climacteric syndrome (as part of combination therapy).

ICD codes

ICD-10 code Indication
E05 Thyrotoxicosis [hyperthyroidism]
F45.3 Somatoform dysfunction of the autonomic nervous system
F48.0 Neurasthenia
F51.0 Nonorganic insomnia
I10 Essential [primary] hypertension
I20 Angina pectoris
I25.8 Other forms of chronic ischemic heart disease
I47.1 Supraventricular tachycardia
I48 Atrial fibrillation and flutter
I49.4 Other and unspecified premature depolarization
I50.0 Congestive heart failure
I70 Atherosclerosis
J06.9 Acute upper respiratory infection, unspecified
J15 Bacterial pneumonia, not elsewhere classified
N95.1 Menopausal and other perimenopausal disorders
N95.3 States associated with artificial menopause
R00.0 Tachycardia, unspecified (including nodal (sinus) NOS)
R07.2 Pain in the heart region
T46.0 Poisoning by cardiac glycosides and drugs of similar action
ICD-11 code Indication
5A02.Z Thyrotoxicosis, unspecified
6A8Z Affective disorders, unspecified
6C20.Z Bodily distress disorder, unspecified
7A00 Chronic insomnia
7A01 Acute insomnia
7A0Z Insomnia disorders, unspecified
BA00.Z Essential hypertension, unspecified
BA40.Z Angina pectoris, unspecified
BA5Z Chronic ischemic heart disease, unspecified
BC81.0 Ectopic atrial tachycardia
BC81.1 Nodal ectopic tachycardia
BC81.20 CTI [cavotricuspid isthmus]-dependent atrial tachycardia by "macro re-entry" mechanism
BC81.21 Atrial tachycardia by "macro re-entry" mechanism not associated with scar or cavotricuspid isthmus
BC81.2Z Atrial tachycardia by "macro re-entry" mechanism, unspecified
BC81.5 Sinoatrial reentrant tachycardia
BC81.7Z Atrioventricular reentrant tachycardia, unspecified
BC81.8 Atrioventricular nodal reentrant tachycardia
BC81.Z Supraventricular tachyarrhythmia, unspecified
BD10 Congestive heart failure
BD40.Z Atherosclerosis of peripheral arteries, unspecified
BE2Y Other specified diseases of the circulatory system
CA07.0 Acute upper respiratory tract infection of unspecified site
CA40.0Z Bacterial pneumonia, unspecified
GA30.00 Menopausal or climacteric states in women
GA30.3 States associated with artificial menopause
MC81.Z Abnormalities of heart rhythm, unspecified
MC86 Precordial pain
NE60 Poisoning by drugs, medicaments or biological substances, not elsewhere classified

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Prepare as an infusion (tea). Place 1-2 grams (approximately 1 tablespoon) of crushed herbal raw material into an enamel or glass vessel.

Pour 200 ml (one cup) of hot boiled water over the raw material. Close the lid and heat in a boiling water bath for 15 minutes.

Cool the infusion at room temperature for 45 minutes. Strain the resulting liquid, then squeeze out the remaining plant material.

Bring the volume of the finished infusion to 200 ml with boiled water. Take the prepared infusion orally, 2-3 times per day.

Take 1/2 to 1/3 cup ( 100-150 ml) per dose. Take 30-40 minutes before meals.

The duration of treatment is determined by the physician based on the disease severity and achieved therapeutic effect.

For functional cardiovascular disorders, the typical treatment course is 3-4 weeks. For chronic heart failure, long-term use may be required.

Do not use the prepared infusion if it becomes cloudy or shows signs of spoilage. Prepare a fresh infusion daily; do not store for more than 24 hours in a cool place.

Adverse Reactions

Possibleallergic reactions; bradycardia (with prolonged use); nausea, vomiting, intestinal colic (when taken on an empty stomach).

Contraindications

Hypersensitivity to the plant.

Use in Pregnancy and Lactation

The possibility of use depends on the specific drug used containing hawthorn flowers and leaves.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle OTC Icon Crataegi flores Herbal raw material: bags 50 g.

Dosage Form, Packaging, and Composition

Herbal raw material 1 bag
Common hawthorn flowers 50 g

50 g – Paper bags.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle OTC Icon Crataegi flores Herbal raw material – powder 2 g: filter-bags 10 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter-bag
Common hawthorn flowers 2 g

2 g – filter-bags (10) – cardboard packs.

Marketing Authorization Holder

Fito-Em Agrarian And Industrial Firm, CJS (Russia)

Dosage Form

Bottle OTC Icon Crataegi flores Herbal raw material – powder 2 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter-bag
Common hawthorn flowers 2 g

2 g – filter-bags (10) – cardboard packs.
2 g – filter-bags (20) – cardboard packs.

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