DexTenol (Ointment) Instructions for Use

Marketing Authorization Holder

Beringer, LLC (Russia)

Manufactured By

DSM Nutritional Products, Ltd. (United Kingdom)

Or

Lok-Beta Pharmaceuticals (India), Private Limited (India)

ATC Code

D03AX03 (Dexpanthenol)

Active Substance

Dexpanthenol (Rec.INN registered by WHO)

Dosage Form

DexTenol

Ointment for external use 5%: tube 30 g

Dosage Form, Packaging, and Composition

Ointment for external use from white to almost white, homogeneous.

30 g – aluminum tubes – cardboard package /instructions for use/ – Over-the-Counter

Clinical-Pharmacological Group

Drug improving tissue regeneration, for external use

Pharmacotherapeutic Group

Tissue repair stimulant

Pharmacological Action

Stimulant of tissue regeneration, belongs to B vitamins. Dexpanthenol is a precursor of pantothenic acid.

In the body, it is converted into pantothenic acid, which is a component of coenzyme A and participates in acetylation processes, carbohydrate and fat metabolism, and in the synthesis of acetylcholine, corticosteroids, and porphyrins; it stimulates the regeneration of the skin and mucous membranes, normalizes cellular metabolism, accelerates mitosis, and increases the strength of collagen fibers.

It has regenerating, metabolic, and weak anti-inflammatory effects.

Data obtained from animal experiments indicate an increase in fibroblast proliferation and the presence of a regenerating effect.

When applied externally and topically, Dexpanthenol is able to compensate for the increased need of damaged skin or mucous membranes for pantothenic acid.

Pharmacokinetics

Dexpanthenol is quickly absorbed by the skin and converted into pantothenic acid.

It binds to blood plasma proteins (mainly to albumin and β-globulin).

Pantothenic acid is not metabolized in the body and is excreted unchanged.

Indications

Violation of the integrity of the skin: healing of burns (including sunburns), minor skin injuries (including abrasions, cuts, cracks); prevention and treatment of dry skin, including as a consequence of dermatitis of various origins; daily care of skin areas most exposed to external factors (face, hands); care of the mammary glands during lactation (cracks and redness of the nipples of the mammary gland); care for infants and babies (diaper rash, diaper dermatitis).

ICD codes

Dosage Regimen

Apply the ointment externally to the affected skin surface or for preventive care.

Lightly rub in the ointment until fully absorbed.

For minor skin injuries, such as abrasions, cuts, and cracks, apply a thin layer 1-2 times daily.

For the treatment of burns, including sunburns, apply 2-4 times daily depending on severity.

To prevent and treat dry skin and dermatitis, apply as needed to maintain skin integrity.

For daily care of exposed skin areas like the face and hands, apply once or twice daily.

For cracked nipples during lactation, apply after each feeding; ensure the area is clean and remove any residue before nursing.

For infant care, including diaper rash and diaper dermatitis, apply with each diaper change to clean, dry skin.

Adjust the frequency of application based on the clinical indication and response to treatment.

Avoid application to heavily exuding wounds or deep, infected lesions without medical supervision.

Adverse Reactions

In very rare cases, allergic reactions are possible.

Contraindications

Hypersensitivity to dexpanthenol.

Use in Pregnancy and Lactation

Can be used during pregnancy and breastfeeding.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.