Mastodon

Dimedrol tablets (Tablets, Solution) Instructions for Use

ATC Code

R06AA02 (Diphenhydramine)

Active Substance

Diphenhydramine (Rec.INN registered by WHO)

Clinical-Pharmacological Group

Histamine H1-receptor blocker. Antiallergic drug

Pharmacotherapeutic Groups

  • H1-histamine receptor blocker
  • Antiallergic agent – H1-histamine receptor blocker

Pharmacological Action

Blocker of histamine H1-receptors. It has antiallergic activity, exerts local anesthetic, antispasmodic, and moderate ganglioblocking action. When taken orally, it causes a sedative and hypnotic effect, exerts a moderate antiemetic effect, and also has central anticholinergic activity.

When administered parenterally to patients with circulating blood volume deficiency, a decrease in blood pressure and an increase in existing hypotension are possible.

When applied topically, it exerts an antiallergic effect.

Pharmacokinetics

It is rapidly absorbed from the gastrointestinal tract. Bioavailability is 50%. Cmax is reached within 20-40 minutes (the highest concentrations are determined in the lungs, spleen, kidneys, liver, brain, and muscles). Plasma protein binding is 98-99%. It penetrates the blood-brain barrier. It is metabolized mainly in the liver, partially in the lungs and kidneys. T1/2 is 4-10 hours. Within 24 hours, it is completely excreted by the kidneys in the form of metabolites conjugated with glucuronic acid. Significant amounts are excreted in breast milk and can cause a sedative effect in infants (a paradoxical reaction characterized by excessive excitability may be observed).

When applied topically, absorption is insignificant; impaired skin integrity increases the absorption of diphenhydramine.

Indications

Allergic conjunctivitis, allergic rhinitis, chronic urticaria, pruritic dermatoses, dermographism, serum sickness; as part of complex therapy for anaphylactic and anaphylactoid reactions, angioedema, and other allergic conditions. Insomnia, chorea, Ménière’s syndrome, seasickness and airsickness, as an antiemetic. Sunburns and first-degree burns; insect bites; skin itching of various origins (except for itching in cholestasis): eczema, chickenpox, allergic skin irritations, contact dermatitis caused by contact with plants.

ICD codes

ICD-10 code Indication
B01 Varicella [chickenpox]
F51.0 Nonorganic insomnia
G10 Huntington's chorea
H10.1 Acute atopic (allergic) conjunctivitis
H81 Vestibular function disorders
H81.0 Ménière's disease
J30.0 Vasomotor rhinitis
J30.1 Allergic rhinitis due to pollen
J30.3 Other allergic rhinitis (perennial allergic rhinitis)
L20.8 Other atopic dermatitis (neurodermatitis, eczema)
L23 Allergic contact dermatitis
L24 Irritant contact dermatitis
L28.0 Lichen simplex chronicus (circumscribed neurodermatitis)
L29 Pruritus
L30.0 Nummular eczema
L50.8 Other urticaria
L55 Sunburn
R11 Nausea and vomiting
T14.0 Superficial injury of unspecified body region (including abrasion, bruise, contusion, hematoma, bite of nonvenomous insect)
T30 Burns and corrosions of unspecified body region
T75.3 Motion sickness
T78.2 Anaphylactic shock, unspecified
T78.3 Angioneurotic edema (Quincke's edema)
T88.7 Unspecified adverse effect of drug or medicament
Z51.4 Preparatory procedures for subsequent treatment or examination, not elsewhere classified
ICD-11 code Indication
1E90.Z Varicella, unspecified
4A84.30 Exercise-induced anaphylaxis
4A84.31 Cold-induced anaphylaxis
4A84.3Z Anaphylaxis caused by unspecified physical factors
4A84.4 Anaphylaxis caused by inhalation of allergens
4A84.5 Anaphylaxis caused by contact with allergens
4A84.6 Secondary anaphylaxis in mast cell disease
4A84.Z Anaphylaxis, unspecified
7A00 Chronic insomnia
7A01 Acute insomnia
7A0Z Insomnia disorders, unspecified
8A01.10 Huntington's chorea
9A06.70 Atopic eczema of the eyelids
9A60.01 Acute atopic conjunctivitis
9A60.02 Allergic conjunctivitis
9A60.0Y Other specified papillary conjunctivitis
9A60.0Z Papillary conjunctivitis, unspecified
AB31.0 Ménière's disease
AB34.Z Unspecified vestibular function disorders
CA08.00 Allergic rhinitis due to pollen
CA08.03 Other allergic rhinitis
CA08.3 Vasomotor rhinitis
EA80.0 Infantile atopic eczema
EA80.1 Childhood atopic eczema
EA80.2 Adult atopic eczema
EA80.Z Atopic eczema, unspecified
EA82 Nummular dermatitis
EA83.00 Lichen simplex of vulva
EA83.01 Lichen simplex of male genital organs
EA83.02 Lichen simplex of perianal area
EA83.0Z Lichen simplex of unspecified location
EA85.20 Atopic hand eczema
EB04 Idiopathic angioedema
EC90.Z Itching, unspecified
EH92 Dermatoses provoked by friction or mechanical impact
EH92.1 Blister due to friction
EK00.Z Allergic contact dermatitis, unspecified
EK02.Z Irritant contact dermatitis, unspecified
MD90 Nausea or vomiting
ND56.0 Superficial injury of unspecified body region
NE11 Burn of unspecified body region
NE60 Poisoning by drugs, medicaments or biological substances, not elsewhere classified
NF08.3 Motion sickness
QB9A Preparatory procedures for subsequent treatment

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Tablets, Solution

It is used orally, parenterally, and topically.

Orally, it is prescribed for adults and children over 14 years of age in a single dose of 50 mg. The regimen and duration of use are determined individually, depending on the indications.

Intravenously or deep intramuscularly, it is prescribed for adults and children over 14 years of age in a single dose of 10-50 mg, the maximum daily dose is 200 mg. For children aged from 7 months to 14 years, the dose is set depending on age.

Topically. Apply to the affected areas of the skin 3-4 times/day.

Adverse Reactions

From the nervous system headache, sedative effect, drowsiness, dizziness, impaired coordination, weakness, confusion, anxiety, agitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesia, neuritis, convulsions.

From the digestive system dryness of the oral mucosa, nausea, vomiting, epigastric pain, anorexia, diarrhea, constipation.

From the respiratory system dryness of the nasal and throat mucosa, increased sputum viscosity, feeling of chest tightness, sneezing, nasal congestion.

From the cardiovascular system palpitations, decreased blood pressure, tachycardia, extrasystole.

From the hematopoietic system hemolytic anemia, thrombocytopenia, agranulocytosis.

From the genitourinary system frequent or difficult urination, urinary retention, early menstruation.

From the sensory organs: visual perception disorder, diplopia, vertigo, tinnitus, acute labyrinthitis.

Allergic reactions: urticaria, skin rash, itching, anaphylactic shock, photosensitivity.

Other : increased sweating, chills.

Contraindications

Hypersensitivity to diphenhydramine.

For systemic use: angle-closure glaucoma, prostatic hypertrophy, stenosing gastric and duodenal ulcer, stenosis of the bladder neck, bronchial asthma, epilepsy; children under 14 years of age (for oral administration); children under 7 months of age (for parenteral administration).

With caution: increased intraocular pressure, hyperthyroidism, arterial hypertension, cardiovascular diseases, bronchopulmonary diseases.

For topical use: simultaneous use of any preparations containing Diphenhydramine; application to large skin surfaces; children under 2 years of age.

With caution: damaged skin at the application site, application to mucous membranes.

Use in Pregnancy and Lactation

During pregnancy and lactation (breastfeeding), Diphenhydramine should be used with caution, strictly according to indications, in cases where the expected therapeutic benefit for the mother outweighs the potential risk to the fetus or breastfed infant.

Significant amounts of diphenhydramine are excreted in breast milk and can cause a sedative effect in infants (a paradoxical reaction characterized by excessive excitability may be observed).

Use in Renal Impairment

It should be used with caution in patients with impaired renal function.

Pediatric Use

It can be used in children according to indications in age-appropriate recommended doses and dosage forms.

Geriatric Use

It should be prescribed with caution to elderly patients to avoid worsening of concomitant diseases.

Special Precautions

During treatment, exposure to solar radiation should be avoided; it is necessary to avoid alcohol consumption.

Effect on ability to drive vehicles and operate machinery

It should be used with caution in patients engaged in potentially hazardous activities requiring increased attention and rapid psychomotor reactions.

Drug Interactions

Concomitant use enhances the effect of ethanol and drugs that depress the central nervous system.

Concomitant use of MAO inhibitors enhances the anticholinergic activity of diphenhydramine.

Antagonistic interaction is noted with simultaneous administration with psychostimulants.

It reduces the effectiveness of apomorphine as an emetic in the treatment of poisoning.

It enhances the anticholinergic effects of drugs with anticholinergic activity.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Marketing Authorization Holder

As-Pharm OJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

As-Pharm OJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

As-Pharm OJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Barnaul Plant of Medical Preparations, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Barnaul Plant of Medical Preparations, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Barnaul Plant of Medical Preparations, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Bryntsalov-A, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Bryntsalov-A, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Bryntsalov-A, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Vostok JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Vostok JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Vostok JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Moscow Pharmaceutical Factory CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Moscow Pharmaceutical Factory CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Moscow Pharmaceutical Factory CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Trading House KhiMoptorg CJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Trading House KhiMoptorg CJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Trading House KhiMoptorg CJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

PharmaDon, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

PharmaDon, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

PharmaDon, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Pharmalena, CJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Pharmalena, CJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Pharmalena, CJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Akrikhin Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Akrikhin Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packaging (1) – cardboard packs.

10 pcs. – contour cell packaging (2) – cardboard packs.

Marketing Authorization Holder

Akrikhin Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Central European Pharmaceutical Company CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Central European Pharmaceutical Company CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Central European Pharmaceutical Company CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Erecton SPC, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Erecton SPC, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Erecton SPC, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol tablets Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Atoll LLC (Russia)

Manufactured By

Ozon, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration transparent, colorless.

1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Barnaul Plant of Medical Preparations, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Tablets 50 mg: 10, 20, 30, or 50 pcs.

Dosage Form, Packaging, and Composition

Tablets white, round, flat-cylindrical, with a bevel.

1 tab.
Diphenhydramine hydrochloride 50 mg

Excipients: sufficient quantity to obtain a tablet weighing 150 mg: lactose monohydrate (milk sugar) – 75 mg, corn starch – 23.154 mg, colloidal silicon dioxide (aerosil) – 0.76 mg, stearic acid – 0.76 mg, water-soluble methylcellulose – 0.326 mg.

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.

Marketing Authorization Holder

Belmedpreparaty, JSC (Republic of Belarus)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Belmedpreparaty RUP (Republic of Belarus)

Dosage Form

Bottle Rx Icon Dimedrol Tablets 50 mg: 10, 20, 30, or 1600 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour non-cell packs (1) – cardboard packs.
10 pcs. – contour non-cell packs (2) – cardboard packs.
10 pcs. – contour non-cell packs (3) – cardboard packs.
10 pcs. – contour non-cell packs (160) – cardboard boxes.

Marketing Authorization Holder

Biosintez, PJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/ml: 1 ml amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Biosintez, PJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour non-cell packs (1) – paper bags.
10 pcs. – contour non-cell packs (2) – cardboard packs.
10 pcs. – dark glass jars (1) – cardboard packs.
20 pcs. – dark glass jars (1) – cardboard packs.

Marketing Authorization Holder

Borisov Plant Of Medical Preparations, PJSC (Republic Of Belarus)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intramuscular administration 10 mg/ml: 1 ml amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intramuscular administration transparent, colorless.

1 ml
Diphenhydramine 10 mg

Excipients: water for injections up to 1 ml.

1 ml – ampoules (10) – cardboard packs.
1 ml – ampoules (10) – blister packs (1) – cardboard packs.

Marketing Authorization Holder

Velpharm, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/1 ml: 1 ml amp. 5 or 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration in the form of a transparent, colorless liquid.

1 ml
Diphenhydramine hydrochloride 10 mg

Excipients: water for injections – up to 1 ml.

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.
1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Velpharm, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Tablets 50 mg: 10, 20, 30, 40, 50, or 60 pcs.

Dosage Form, Packaging, and Composition

Tablets white, round, flat-cylindrical, with a bevel.

1 tab.
Diphenhydramine hydrochloride 50 mg

Excipients: lactose monohydrate (milk sugar), potato starch, talc, calcium stearate.

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (4) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (6) – cardboard packs.
10 pcs. – polymer jars (1) – cardboard packs.
20 pcs. – polymer jars (1) – cardboard packs.
30 pcs. – polymer jars (1) – cardboard packs.
40 pcs. – polymer jars (1) – cardboard packs.
50 pcs. – polymer jars (1) – cardboard packs.
60 pcs. – polymer jars (1) – cardboard packs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.
1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Tablets 50 mg: 10, 20, 30, or 50 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour non-cell packs.

Marketing Authorization Holder

N.A. Semashko Moscow Chemical Pharmaceutical Preparations, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.
1 ml – ampoules (5) – plastic packs (2) – cardboard packs.

Marketing Authorization Holder

Novosibkhimpharm, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Samson-Med LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

Excipients : water for injections up to 1 ml.

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Ferment Firm, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration in the form of a transparent, colorless liquid.

1 ml
Diphenhydramine hydrochloride 10 mg

Excipients : water for injections – up to 1 ml.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Mir Chemical and Pharmaceutical Concern, LLC (Russia)

Manufactured By

Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)

Or

NPC Eskom, PJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Solution for intravenous and intramuscular administration 10 mg/ml: amp. 1 ml 3, 5, 10, 20, 50, or 100 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration in the form of a transparent colorless liquid.

1 ml
Diphenhydramine hydrochloride 10 mg

Excipients : water for injections – up to 1 ml.

1 ml – neutral glass ampoules (3) – cardboard packs.

1 ml – neutral glass ampoules (5) – cardboard packs.

1 ml – neutral glass ampoules (10) – cardboard packs.

1 ml – neutral glass ampoules (20) – cardboard packs.

1 ml – neutral glass ampoules (50) – cardboard packs.

1 ml – neutral glass ampoules (100) – cardboard packs.

Marketing Authorization Holder

Avexima JSC (Russia)

Manufactured By

Avexima Siberia LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Avexima Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – non-cell contour packs.

10 pcs. – non-cell contour packs (1) – cardboard packs.

10 pcs. – non-cell contour packs (2) – cardboard packs.

Marketing Authorization Holder

Obnovlenie Pfc, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Bufus Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard boxes.

Marketing Authorization Holder

Obnovlenie Pfc, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Renewal Solution for intravenous and intramuscular administration 10 mg/ml

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration

1 ml
Diphenhydramine hydrochloride 10 mg

1 ml – ampoules (10 pcs.) – cardboard packs – Prescription only

1 ml – ampoules (100 pcs.) – cardboard boxes – for hospitals

1 ml – ampoules (20 pcs.) – cardboard packs – Prescription only

1 ml – ampoules (3 pcs.) – cardboard packs – Prescription only

1 ml – ampoules (5 pcs.) – cardboard packs – Prescription only

1 ml – ampoules (50 pcs.) – cardboard boxes – for hospitals

2 ml – ampoules (10 pcs.) – cardboard packs – Prescription only

2 ml – ampoules (100 pcs.) – cardboard boxes – for hospitals

2 ml – ampoules (20 pcs.) – cardboard packs – Prescription only

2 ml – ampoules (3 pcs.) – cardboard packs – Prescription only

2 ml – ampoules (5 pcs.) – cardboard packs – Prescription only

2 ml – ampoules (50 pcs.) – cardboard boxes – for hospitals

3 ml – ampoules (10 pcs.) – cardboard packs – Prescription only

3 ml – ampoules (100 pcs.) – cardboard boxes – for hospitals

3 ml – ampoules (20 pcs.) – cardboard packs – Prescription only

3 ml – ampoules (3 pcs.) – cardboard packs – Prescription only

3 ml – ampoules (5 pcs.) – cardboard packs – Prescription only

3 ml – ampoules (50 pcs.) – cardboard boxes – for hospitals

5 ml – ampoules (10 pcs.) – cardboard packs – Prescription only

5 ml – ampoules (100 pcs.) – cardboard boxes – for hospitals

5 ml – ampoules (20 pcs.) – cardboard packs – Prescription only

5 ml – ampoules (3 pcs.) – cardboard packs – Prescription only

5 ml – ampoules (5 pcs.) – cardboard packs – Prescription only

5 ml – ampoules (50 pcs.) – cardboard boxes – for hospitals

Marketing Authorization Holder

Bryntsalov-A, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Organika, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Samson-Med LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

St. Petersburg Research Institute of Vaccines and Sera of the FMBA, FSUE (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Pharmstandard-Ufimsky Vitaminny Zavod OJSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Erecton SPC, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol solution for injection 1% Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 5, 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (5) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (1) – cardboard packs.

1 ml – ampoules (10) – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Velpharm, LLC (Russia)

Manufactured By

Velpharm, LLC (Russia)

Or

Velpharm-M, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol Velpharm Tablets 50 mg: 10, 20, 30, 40, 50, or 60 pcs.

Dosage Form, Packaging, and Composition

Tablets white, round, flat-cylindrical, with a bevel.

1 tab.
Diphenhydramine hydrochloride 50 mg

Excipients : lactose monohydrate (milk sugar), potato starch, talc, calcium stearate.

10 pcs. – contour cell packs (1) – cardboard packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (3) – cardboard packs.

10 pcs. – contour cell packs (4) – cardboard packs.

10 pcs. – contour cell packs (5) – cardboard packs.

10 pcs. – contour cell packs (6) – cardboard packs.

10 pcs. – polymer jars (1) – cardboard packs.

20 pcs. – polymer jars (1) – cardboard packs.

30 pcs. – polymer jars (1) – cardboard packs.

40 pcs. – polymer jars (1) – cardboard packs.

50 pcs. – polymer jars (1) – cardboard packs.

60 pcs. – polymer jars (1) – cardboard packs.

Marketing Authorization Holder

RosMedPreparaty, CJS (Russia)

Dosage Form

Bottle Rx Icon Dimedrol-Ros Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – non-cell contour packaging (1) – cardboard packs.
10 pcs. – non-cell contour packaging (2) – cardboard packs.
10 pcs. – blister contour packaging (1) – cardboard packs.
10 pcs. – blister contour packaging (2) – cardboard packs.

Marketing Authorization Holder

Uralbiopharm, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol-UBF Tablets 50 mg: 10, 20, 30, 40, 50, 60, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – blister contour packaging (1) – cardboard packs.
10 pcs. – blister contour packaging (2) – cardboard packs.
10 pcs. – blister contour packaging (3) – cardboard packs.
10 pcs. – blister contour packaging (5) – cardboard packs.
10 pcs. – polymer jars (1) – cardboard packs.
20 pcs. – polymer jars (1) – cardboard packs.
30 pcs. – polymer jars (1) – cardboard packs.
40 pcs. – polymer jars (1) – cardboard packs.
50 pcs. – polymer jars (1) – cardboard packs.
60 pcs. – polymer jars (1) – cardboard packs.
100 pcs. – polymer jars (1) – cardboard packs.

Marketing Authorization Holder

UfaVITA, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol-UVI Tablets 50 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 50 mg

10 pcs. – non-cell contour packaging (1) – cardboard packs.
10 pcs. – non-cell contour packaging (2) – cardboard packs.
10 pcs. – blister contour packaging (1) – cardboard packs.
10 pcs. – blister contour packaging (2) – cardboard packs.

Marketing Authorization Holder

UfaVITA, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol-UVI Tablets 30 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 30 mg

10 pcs. – non-cell contour packaging (1) – cardboard packs.
10 pcs. – non-cell contour packaging (2) – cardboard packs.
10 pcs. – blister contour packaging (1) – cardboard packs.
10 pcs. – blister contour packaging (2) – cardboard packs.

Marketing Authorization Holder

UfaVITA, JSC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol-UVI Tablets 100 mg: 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Diphenhydramine 100 mg

10 pcs. – non-cell contour packaging (1) – cardboard packs.
10 pcs. – non-cell contour packaging (2) – cardboard packs.
10 pcs. – blister contour packaging (1) – cardboard packs.
10 pcs. – blister contour packaging (2) – cardboard packs.

Marketing Authorization Holder

Vial, LLC (Russia)

Manufactured By

Sishui Xierkang Pharmaceutical, Co. Ltd. (China)

Dosage Form

Bottle Rx Icon Dimedrol-Vial Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Vial, LLC (Russia)

Manufactured By

Sishui Xierkang Pharmaceutical, Co. Ltd. (China)

Labeled By

OZON, LLC (Russia)

Dosage Form

Bottle Rx Icon Dimedrol-Vial Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs. (packaged by Ozon)

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Vial, LLC (Russia)

Manufactured By

Shandong Shenglu Pharmaceutical, Co.Ltd. (China)

Dosage Form

Bottle Rx Icon Dimedrol-Vial Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Marketing Authorization Holder

Vial, LLC (Russia)

Manufactured By

NORTH CHINA PHARMACEUTICAL CORPORATION (China)

Dosage Form

Bottle Rx Icon Dimedrol-Vial Solution for intravenous and intramuscular administration 10 mg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration 1 ml
Diphenhydramine 10 mg

1 ml – ampoules (10) – cardboard packs.

Table of Contents

TABLE OF CONTENTS