Dimicol (Ointment) Instructions for Use

Marketing Authorization Holder

Ivanovo Pharmaceutical Factory PJSC (Russia)

ATC Code

D06C (Antibiotics and chemotherapeutic agents in combination with other drugs)

Active Substances

Chloramphenicol (Rec.INN registered by WHO)

Dioxomethyltetrahydropyrimidine (Grouping name)

Dosage Form

Dimicol

Ointment for external use 40 mg/g+7.5 mg/g

Dosage Form, Packaging, and Composition

Ointment for external use

100 g – jars – cardboard packs – By prescription
100 g – jars 9-300 pcs. – cardboard boxes – for hospitals
100 g – tubes – cardboard packs – By prescription
100 g – tubes 9-300 pcs. – cardboard boxes – for hospitals
25 g – jars – cardboard packs – By prescription
25 g – jars 9-300 pcs. – cardboard boxes – for hospitals
25 g – tubes – cardboard packs – By prescription
25 g – tubes 9-300 pcs. – cardboard boxes – for hospitals
30 g – jars – cardboard packs – By prescription
30 g – jars 9-300 pcs. – cardboard boxes – for hospitals
30 g – tubes – cardboard packs – By prescription
30 g – tubes 9-300 pcs. – cardboard boxes – for hospitals
40 g – jars – cardboard packs – By prescription
40 g – jars 9-300 pcs. – cardboard boxes – for hospitals
40 g – tubes – cardboard packs – By prescription
40 g – tubes 9-300 pcs. – cardboard boxes – for hospitals
50 g – jars – cardboard packs – By prescription
50 g – jars 9-300 pcs. – cardboard boxes – for hospitals
50 g – tubes – cardboard packs – By prescription
50 g – tubes 9-300 pcs. – cardboard boxes – for hospitals

Clinical-Pharmacological Group

A drug with antibacterial and tissue regeneration-improving action for external use

Pharmacotherapeutic Group

Antibiotics and antimicrobial agents used in dermatology; antibiotics and antimicrobial agents, combinations

Pharmacological Action

A combined drug for topical use, has anti-inflammatory (dehydrating) and antimicrobial action, is active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli).

It easily penetrates deep into tissues without damaging biological membranes and stimulates regeneration processes.

The antibacterial action is preserved in the presence of pus and necrotic masses. Dioxomethyltetrahydropyrimidine, by normalizing nucleic acid metabolism, stimulates regeneration processes in wounds, tissue growth and granulation maturation, epithelialization, and has an anti-inflammatory (dehydrating) effect.

Indications

Purulent wounds (including those infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process.

ICD codes

Dosage Regimen

Apply the ointment topically only.

Use the drug to impregnate sterile gauze napkins.

Loosely fill the wound cavity with the impregnated napkins.

Alternatively, introduce the ointment into purulent cavities through a drainage tube using a syringe.

Apply dressings daily or as directed by a physician.

Prior to application, cleanse the wound surface of necrotic tissue and purulent exudate.

The duration of treatment is determined by the rate of wound cleansing and the appearance of granulation tissue.

Discontinue use upon achieving a clean, granulating wound bed.

For extensive wounds or prolonged therapy, monitor the patient’s clinical status and perform a clinical blood test.

Avoid contact with eyes and mucous membranes.

Do not apply to extensive body surface areas for a prolonged period without medical supervision.

Adverse Reactions

Allergic reactions skin rashes.

Contraindications

Children under 1 year of age (in newborns, the biotransformation of chloramphenicol occurs more slowly than in adults); hypersensitivity to the components of the combination.

With caution

Pregnancy, lactation period (breastfeeding).

Use in Pregnancy and Lactation

Use during pregnancy is possible if the benefit to the mother outweighs the risk to the fetus.

During lactation, either the use of the drug should be discontinued or breastfeeding should be stopped.

Pediatric Use

Use is contraindicated in children under 1 year of age (in newborns, the biotransformation of chloramphenicol occurs more slowly than in adults).

Special Precautions

When applied to extensive areas of the skin and during long courses of treatment, it is necessary to perform a clinical blood test.

Storage Conditions

Store at 2°C (36°F) to 15°C (59°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.