Hematogen (Pastilles, Lozenges) Instructions for Use

ATC Code

B03AE10 (Iron preparations in combination with other drugs)

Clinical-Pharmacological Group

Antianemic drug. Vitamin complex with a trace element

Pharmacotherapeutic Group

Iron preparation + other preparations

Pharmacological Action

A means for the correction of metabolic processes. It is a source of high-quality protein, fats, carbohydrates, and minerals, which are contained in proportions close to the composition of human blood. The biologically complete protein contains all amino acids in a ratio optimal for the body.

It stimulates hematopoiesis, promotes the absorption of iron in the intestine, increases the hemoglobin content in the blood, and increases the plasma ferritin level.

Indications

Use for the following conditions.

• Iron deficiency anemia for the purpose of stimulating hematopoiesis and correcting hemoglobin and ferritin levels.
• States of inadequate or unbalanced nutrition to provide a source of complete protein, fats, carbohydrates, and minerals.
• The convalescence period after infectious and other debilitating illnesses to support recovery and metabolic processes.

ICD codes

Dosage Regimen

Administer orally. Adhere strictly to the recommended daily intake to avoid exceeding the safe level of iron and other components.

For the pastilles/lozenges dosage form: take 1 to 2 pastilles two to three times per day. The total daily dose should not exceed 6 pastilles. Suck or chew the pastilles.

Adverse Reactions

Adverse reactions are generally infrequent and mild, primarily related to the gastrointestinal system due to iron content.

From the digestive system: nausea, diarrhea, epigastric discomfort. These effects are often dose-dependent. Allergic reactions, including skin rash, itching, and urticaria, may occur in individuals with hypersensitivity to any component of the formulation.

Drug Interactions

Concurrent administration with other oral iron-containing products increases the risk of cumulative iron overload and gastrointestinal side effects.

The absorption of iron may be reduced when taken concomitantly with tetracycline antibiotics, quinolones, bisphosphonates, levothyroxine, and antacids containing aluminum, calcium, or magnesium. Maintain a minimum 2-hour interval between the intake of this drug and these medications.

Avoid concurrent use with angiotensin-converting enzyme (ACE) inhibitors, as iron may potentiate their cough-inducing effect.

Contraindications

Do not use under the following conditions.

• Known hypersensitivity to any of the active or excipient components of the formulation.
• All types of anemia not associated with iron deficiency (e.g., hemolytic, megaloblastic, aplastic anemia).
• Disorders of carbohydrate metabolism, including diabetes mellitus, due to the sugar content in the pastilles.
• Hemochromatosis, hemosiderosis, and other conditions associated with iron overload.

Overdose

Acute overdose is characterized by symptoms of iron intoxication, which may manifest in several phases.

Early symptoms (within 6 hours) include nausea, vomiting, abdominal pain, diarrhea, and lethargy. Later stages (after 6-24 hours) may involve metabolic acidosis, drowsiness, and shock. Gastrointestinal bleeding and hepatic necrosis are possible in severe cases.

Seek immediate medical attention. Treatment is symptomatic and supportive; gastric lavage may be considered. In severe intoxication, administer a specific iron chelator as prescribed.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.