Ibuprofen (Tablets, Capsules, Suppositories, Suspension) Instructions for Use
ATC Code
M01AE01 (Ibuprofen)
Active Substance
Ibuprofen (Rec.INN registered by WHO)
Clinical-Pharmacological Group
NSAID
Pharmacotherapeutic Group
Anti-inflammatory and antirheumatic drugs; non-steroidal anti-inflammatory and antirheumatic drugs; propionic acid derivatives
Pharmacological Action
NSAID, a derivative of phenylpropionic acid. It has anti-inflammatory, analgesic, and antipyretic effects.
The mechanism of action is associated with the inhibition of COX activity, the main enzyme in the metabolism of arachidonic acid, which is a precursor of prostaglandins that play a major role in the pathogenesis of inflammation, pain, and fever.
The analgesic effect is due to both a peripheral mechanism (indirectly, through suppression of prostaglandin synthesis) and a central mechanism (inhibition of prostaglandin synthesis in the central and peripheral nervous system). It suppresses platelet aggregation.
Pharmacokinetics
When taken orally, Ibuprofen is almost completely absorbed from the gastrointestinal tract. Simultaneous food intake slows down the rate of absorption. It is metabolized in the liver (90%). The half-life (T1/2) is 2-3 hours. 80% of the dose is excreted in the urine, mainly in the form of metabolites (70%), 10% unchanged; 20% is excreted through the intestines in the form of metabolites.
Indications
Symptomatic treatment as an anti-inflammatory and antipyretic agent: inflammatory and degenerative diseases of the joints and spine (including rheumatic and rheumatoid arthritis, ankylosing spondylitis, osteoarthritis), joint syndrome in acute gout, psoriatic arthritis, tendinitis, bursitis, radiculitis, traumatic inflammation of soft tissues and the musculoskeletal system.
Neuralgia, myalgia, pain syndrome in infectious and inflammatory diseases of the ENT organs, adnexitis, algodysmenorrhea, headache and toothache.
Fever in infectious and inflammatory diseases, in childhood infections, in post-vaccination reactions in children (in appropriate dosage forms).
ICD codes
| ICD-10 code | Indication |
| H92.0 | Otalgia |
| K08.8 | Other specified disorders of teeth and supporting structures (including toothache) |
| M05 | Seropositive rheumatoid arthritis |
| M07 | Psoriatic and enteropathic arthropathies |
| M10 | Gout |
| M15 | Polyosteoarthritis |
| M19.9 | Unspecified arthrosis |
| M25.5 | Pain in joint |
| M42 | Spinal osteochondrosis |
| M45 | Ankylosing spondylitis |
| M47 | Spondylosis |
| M54 | Dorsalgia |
| M54.1 | Radiculopathy |
| M54.3 | Sciatica |
| M54.4 | Lumbago with sciatica |
| M65 | Synovitis and tenosynovitis |
| M70 | Soft tissue disorders related to use, overuse, and pressure |
| M71 | Other bursopathies |
| M79.1 | Myalgia |
| M79.2 | Neuralgia and neuritis, unspecified |
| N70 | Salpingitis and oophoritis |
| N94.4 | Primary dysmenorrhea |
| N94.5 | Secondary dysmenorrhea |
| R07.0 | Pain in throat |
| R50 | Fever of unknown origin |
| R51 | Headache |
| R52.0 | Acute pain |
| R52.2 | Other chronic pain |
| T14.3 | Dislocation, sprain and strain of joint and ligament of unspecified body region |
| T14.9 | Injury, unspecified |
| T88.1 | Other complications following immunization, not elsewhere classified |
| ICD-11 code | Indication |
| 8A8Z | Headache disorders, unspecified |
| 8B93.Z | Radiculopathy, unspecified |
| 8E4A.1 | Paraneoplastic or autoimmune diseases of the peripheral or autonomic nervous system |
| AB70.2 | Otalgia |
| DA0A.Z | Diseases of teeth and supporting structures, unspecified |
| FA05 | Polyosteoarthritis |
| FA0Z | Osteoarthritis, unspecified |
| FA20.0 | Seropositive rheumatoid arthritis |
| FA21.Z | Psoriatic arthritis, unspecified |
| FA25 | Gout |
| FA85.Z | Defects of vertebral end-plates, unspecified |
| FA8Z | Degenerative disease of spine, unspecified |
| FA92.0Z | Ankylosing spondylitis, unspecified |
| FB40.Z | Tenosynovitis, unspecified |
| FB50.1 | Bursitis associated with use, overuse or pressure |
| FB50.Z | Bursitis, unspecified |
| FB56 | Specified soft tissue diseases, not elsewhere classified |
| FB56.2 | Myalgia |
| GA07.Z | Salpingitis and oophoritis, unspecified |
| GA34.3 | Dysmenorrhea |
| LA30.5Z | Anomalies of tooth resorption or loss, unspecified |
| MD36.0 | Pain in throat |
| ME82 | Pain in joint |
| ME84.20 | Lumbago with sciatica |
| ME84.3 | Sciatica |
| ME84.Z | Back pain, unspecified |
| MG26 | Fever of other or unknown origin |
| MG30.Z | Chronic pain syndrome, unspecified |
| MG31.Z | Acute pain, unspecified |
| ND56.3 | Dislocation, sprain or strain of unspecified body region |
| ND56.Z | Unspecified injury of unspecified part of trunk, limb or body region |
| NE80.Z | Injury or harm arising from infusion, transfusion, or therapeutic injection, not elsewhere classified, unspecified |
Dosage Regimen
| The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen. |
Tablets, Capsules, Suspension
Take orally. The individual dosage regimen depends on the indications, severity of clinical manifestations, and the patient’s age.
A single dose for adults and children over 6 years of age is 200-400 mg. It can be taken 3-4 times a day.
The maximum daily dose for adults is 1200 mg; for children aged 12-17 years – 1000 mg; for children aged 6 to 12 years – 800 mg.
For children under 6 years of age, the dose depends on the child’s age and body weight. The maximum daily dose should not exceed 30 mg/kg of body weight with intervals between doses of 6-8 hours.
| Age | Body Weight | Dosage Regimen | Maximum Daily Dose |
| 3-6 months | 5 kg-7.6 kg | 50 mg up to 3 times/day | 150 mg |
| 6-12 months | 7.7-9 kg | 50 mg up to 3-4 times/day | 200 mg |
| 1-3 years | 10-16 kg | 100 mg up to 3 times/day | 300 mg |
| 4-6 years | 17-20 kg | 150 mg up to 3 times/day | 450 mg |
Suppositories
Apply rectally.
The dose depends on the child’s age and body weight. The maximum daily dose should not exceed 30 mg/kg of body weight with intervals between doses of 6-8 hours.
The duration of treatment is no more than 3 days.
Adverse Reactions
From the hematopoietic system: very rarely – blood disorders ( anemia, leukopenia, aplastic anemia, hemolytic anemia, thrombocytopenia, pancytopenia, agranulocytosis).
From the immune system: infrequently – hypersensitivity reactions – nonspecific allergic reactions and anaphylactic reactions, respiratory reactions ( bronchial asthma, including its exacerbation, bronchospasm, dyspnea), skin reactions ( itching, urticaria, purpura, angioedema, exfoliative and bullous dermatoses, including toxic epidermal necrolysis (Lyell’s syndrome), Stevens-Johnson syndrome, erythema multiforme), allergic rhinitis, eosinophilia; very rarely – severe hypersensitivity reactions, including swelling of the face, tongue and larynx, dyspnea, tachycardia, arterial hypotension (anaphylaxis, angioedema or severe anaphylactic shock).
From the digestive system: infrequently – abdominal pain, nausea, dyspepsia (including heartburn, bloating); rarely – diarrhea, flatulence, constipation, vomiting; very rarely – peptic ulcer, perforation or gastrointestinal bleeding, melena, hematemesis, in some cases fatal, especially in elderly patients, ulcerative stomatitis, gastritis; frequency unknown – exacerbation of colitis and Crohn’s disease.
From the liver and biliary tract: very rarely – impaired liver function, increased activity of liver transaminases, hepatitis and jaundice.
From the urinary system: very rarely – acute renal failure (compensated and decompensated), especially with long-term use, in combination with an increase in plasma urea concentration and the appearance of edema, hematuria and proteinuria; nephritic syndrome, nephrotic syndrome, papillary necrosis, interstitial nephritis, cystitis.
From the nervous system: infrequently – headache; very rarely – aseptic meningitis.
From the cardiovascular system: frequency unknown – heart failure, peripheral edema; with long-term use, increased risk of thrombotic complications (e.g., myocardial infarction, stroke), increased blood pressure.
From the respiratory system: frequency unknown – bronchial asthma; bronchospasm; dyspnea.
From laboratory parameters: possible – decrease in hematocrit or hemoglobin, increased bleeding time, decrease in plasma glucose concentration, decrease in creatinine clearance, increase in plasma creatinine concentration, increase in liver transaminase activity.
Contraindications
Hypersensitivity to ibuprofen; erosive and ulcerative lesions of the gastrointestinal tract in the acute phase or active peptic ulcer bleeding or history thereof (2 or more confirmed episodes of peptic ulcer or peptic ulcer bleeding); history of gastrointestinal bleeding or perforation provoked by NSAIDs; severe heart failure (NYHA functional class IV); severe impairment of renal and/or hepatic function; optic nerve diseases, “aspirin triad”, blood disorders; period after coronary artery bypass surgery; intracranial or other bleeding; hemophilia and other coagulation disorders (including hypocoagulation), hemorrhagic diatheses; third trimester of pregnancy.
With caution: simultaneous use of other NSAIDs; history of a single episode of gastric and duodenal ulcer or gastrointestinal ulcer bleeding; gastritis, enteritis, colitis, presence of Helicobacter pylori infection, ulcerative colitis; bronchial asthma or allergic diseases in the acute phase or history thereof; systemic lupus erythematosus or mixed connective tissue disease (Sharp’s syndrome) – increased risk of aseptic meningitis; chickenpox; renal failure, including with dehydration (creatinine clearance less than 30-60 ml/min), nephrotic syndrome, hepatic failure, liver cirrhosis with portal hypertension; hyperbilirubinemia; arterial hypertension and/or heart failure; cerebrovascular diseases; blood disorders of unknown etiology (leukopenia and anemia); severe somatic diseases; dyslipidemia/hyperlipidemia; diabetes mellitus; peripheral arterial diseases; smoking; frequent alcohol consumption; simultaneous use of drugs that may increase the risk of ulcers or bleeding, in particular, oral corticosteroids (including prednisolone), anticoagulants (including warfarin), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) or antiplatelet agents (including acetylsalicylic acid, clopidogrel); first and second trimester of pregnancy; breastfeeding period; elderly age.
Use in Pregnancy and Lactation
Use during pregnancy and breastfeeding is contraindicated.
Use in Hepatic Impairment
Contraindicated in severe hepatic impairment. Use with caution in concomitant liver diseases.
Use in Renal Impairment
Contraindicated in severe renal impairment. Use with caution in concomitant kidney diseases.
Pediatric Use
Can be used according to indications in recommended doses.
Geriatric Use
Should be prescribed with caution to elderly patients to avoid worsening of concomitant diseases.
Elderly patients have an increased frequency of adverse reactions when using NSAIDs, especially gastrointestinal bleeding and perforations, in some cases fatal.
Special Precautions
It is recommended to prescribe Ibuprofen for the shortest possible course and at the minimum effective dose necessary to relieve symptoms. If systemic use is necessary for more than 10 days, a doctor should be consulted.
During long-term treatment, monitoring of the peripheral blood picture and the functional state of the liver and kidneys is necessary. If symptoms of gastropathy appear, careful monitoring is indicated, including esophagogastroduodenoscopy, complete blood count (hemoglobin determination), stool test for occult blood.
The use of NSAIDs in patients with chickenpox may be associated with an increased risk of developing severe purulent complications of infectious and inflammatory diseases of the skin and subcutaneous fat (e.g., necrotizing fasciitis). Therefore, it is recommended to avoid the use of ibuprofen for chickenpox.
Ibuprofen suppresses COX and prostaglandin synthesis, affects ovulation, disrupting female reproductive function (reversible after discontinuation of treatment).
Effect on the ability to drive vehicles and machinery
Patients who experience dizziness, drowsiness, lethargy, or visual disturbances when taking ibuprofen should avoid driving vehicles and other activities that require high concentration and speed of psychomotor reactions.
Drug Interactions
With simultaneous use, Ibuprofen reduces the effect of antihypertensive agents (ACE inhibitors, beta-blockers), diuretics (furosemide, hydrochlorothiazide).
With simultaneous use with anticoagulants, their effect may be enhanced.
With simultaneous use with corticosteroids, the risk of adverse effects from the gastrointestinal tract increases.
With simultaneous use, Ibuprofen may displace from plasma protein binding indirect anticoagulants (acenocoumarol), hydantoin derivatives (phenytoin), oral hypoglycemic sulfonylurea derivatives.
With simultaneous use with amlodipine, a slight decrease in the antihypertensive effect of amlodipine is possible; with acetylsalicylic acid – the concentration of ibuprofen in plasma decreases; with baclofen – a case of increased toxic effect of baclofen has been described.
With simultaneous use with warfarin, an increase in bleeding time is possible, microhematuria and hematomas have also been observed; with captopril – a decrease in the antihypertensive effect of captopril is possible; with cholestyramine – a moderately pronounced decrease in the absorption of ibuprofen.
With simultaneous use with lithium carbonate, the concentration of lithium in plasma increases.
With simultaneous use with magnesium hydroxide, the initial absorption of ibuprofen increases; with methotrexate – the toxicity of methotrexate increases.
Simultaneous use of NSAIDs and cardiac glycosides may lead to worsening of heart failure, decreased glomerular filtration rate, and increased concentration of cardiac glycosides in plasma.
There is evidence of a likely increase in the plasma concentration of methotrexate when using NSAIDs.
With simultaneous use of NSAIDs and cyclosporine, the risk of nephrotoxicity increases.
NSAIDs may reduce the effectiveness of mifepristone, so NSAIDs should be started no earlier than 8-12 days after the end of mifepristone use.
With simultaneous use of NSAIDs and tacrolimus, an increased risk of nephrotoxicity is possible.
Simultaneous use of NSAIDs and zidovudine may lead to increased hematotoxicity. There are data on an increased risk of hemarthrosis and hematomas in HIV-positive patients with hemophilia receiving combined treatment with zidovudine and ibuprofen.
In patients receiving combined treatment with NSAIDs and quinolone antibiotics, the risk of seizures may increase.
In patients receiving NSAIDs and myelotoxic drugs simultaneously, hematotoxicity is enhanced.
With simultaneous use of ibuprofen and cefamandole, cefoperazone, cefotetan, valproic acid, plicamycin, the frequency of hypoprothrombinemia development increases.
With simultaneous use of ibuprofen and drugs that block tubular secretion, a decrease in excretion and an increase in plasma concentration of ibuprofen are noted.
With simultaneous use of ibuprofen and inducers of microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants), the production of hydroxylated active metabolites increases, increasing the risk of severe intoxications.
Storage Conditions
Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.
Dispensing Status
Over-the-Counter
Important Safety Information
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.
Medical DisclaimerBrand (or Active Substance), Marketing Authorisation Holder, Dosage Form
Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs.
Marketing Authorization Holder
Bryntsalov-A, JSC (Russia)
Dosage Form
 |
Ibuprofen tablets 0.2 | Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
20 pcs. – contour cell packs (1) – cardboard packs.
20 pcs. – contour cell packs (2) – cardboard packs.
50 pcs. – contour cell packs (1) – cardboard packs.
Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs.
Marketing Authorization Holder
Dalkhimpharm, JSC (Russia)
Dosage Form
|
Ibuprofen tablets 0.2 | Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
20 pcs. – contour cell packs (1) – cardboard packs.
20 pcs. – contour cell packs (2) – cardboard packs.
50 pcs. – contour cell packs (1) – cardboard packs.
Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs.
Marketing Authorization Holder
Canonpharma Production, CJS (Russia)
Dosage Form
|
Ibuprofen tablets 0.2 | Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
20 pcs. – contour cell packs (1) – cardboard packs.
20 pcs. – contour cell packs (2) – cardboard packs.
50 pcs. – contour cell packs (1) – cardboard packs.
Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs.
Marketing Authorization Holder
Trading House KhiMoptorg CJSC (Russia)
Dosage Form
|
Ibuprofen tablets 0.2 | Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
20 pcs. – contour cell packs (1) – cardboard packs.
20 pcs. – contour cell packs (2) – cardboard packs.
50 pcs. – contour cell packs (1) – cardboard packs.
Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs.
Marketing Authorization Holder
FP Obolenskoe, JSC (Russia)
Dosage Form
|
Ibuprofen tablets 0.2 | Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
20 pcs. – contour cell packs (1) – cardboard packs.
20 pcs. – contour cell packs (2) – cardboard packs.
50 pcs. – contour cell packs (1) – cardboard packs.
Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs.
Marketing Authorization Holder
Erecton SPC, LLC (Russia)
Dosage Form
|
Ibuprofen tablets 0.2 | Film-coated tablets, 200 mg: 20, 40, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
20 pcs. – contour cell packs (1) – cardboard packs.
20 pcs. – contour cell packs (2) – cardboard packs.
50 pcs. – contour cell packs (1) – cardboard packs.
Capsules 200 mg: 1, 2, 4, 6, 8, 10, 12, 16, 18, 20, 24, 30 or 60 pcs.
Capsules 400 mg: 1, 2, 4, 6, 8, 10, 12, 16, 18, 20, 24, 30 or 60 pcs.
Marketing Authorization Holder
Canonpharma Production, CJS (Russia)
Dosage Forms
|
Ibuprofen Canon | Capsules 200 mg: 1, 2, 4, 6, 8, 10, 12, 16, 18, 20, 24, 30 or 60 pcs. |
| Capsules 400 mg: 1, 2, 4, 6, 8, 10, 12, 16, 18, 20, 24, 30 or 60 pcs. |
Dosage Form, Packaging, and Composition
Capsules soft, gelatin, oval-shaped, red in color; capsule contents – a clear liquid from pink to red.
| 1 caps. | |
| Ibuprofen | 200 mg |
Excipients: purified water – 25 mg, potassium hydroxide – 25 mg, macrogol 600 – 211 mg.
Soft gelatin capsule shell 190 mg, including: glycerol 48.98 mg, gelatin 114.75 mg, methylparaben 0.17 mg, sorbitol 25.7 mg, dye Ponceau 4R 0.4 mg.
1 pc. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
2 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
4 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
4 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
4 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
6 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
6 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
6 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
8 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
8 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
8 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
10 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
10 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
10 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
20 pcs. – polymer polyethylene jars – cardboard packs.
30 pcs. – polymer polyethylene jars – cardboard packs.
60 pcs. – polymer polyethylene jars – cardboard packs.
Capsules soft, gelatin, oval-shaped, red in color; capsule contents – a clear liquid from pink to red.
| 1 caps. | |
| Ibuprofen | 400 mg |
Excipients: purified water – 50 mg, potassium hydroxide – 50 mg, macrogol 600 – 422 mg.
Soft gelatin capsule shell 380 mg, including: glycerol 97.96 mg, gelatin 229.5 mg, methylparaben 0.34 mg, sorbitol 51.4 mg, dye Ponceau 4R 0.8 mg.
1 pc. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
2 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
4 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
4 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
4 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
6 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
6 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
6 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
8 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
8 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
8 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
10 pcs. – contour cell packs (PVC/PVDC/aluminum foil) – cardboard packs.
10 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (2) – cardboard packs.
10 pcs. – contour cell packs (PVC/PVDC/aluminum foil) (3) – cardboard packs.
20 pcs. – jars – cardboard packs.
30 pcs. – jars – cardboard packs.
60 pcs. – jars – cardboard packs.
Suspension for oral administration (for children) 100 mg/5 ml: fl. 100 ml, 150 ml or 200 ml in a set with a dosing syringe
Marketing Authorization Holder
Danson-BG (Bulgaria)
Manufactured By
Vetprom, AD (Bulgaria)
Dosage Form
|
Ibuprofen DS | Suspension for oral administration (for children) 100 mg/5 ml: fl. 100 ml, 150 ml or 200 ml in a set with a dosing syringe |
Dosage Form, Packaging, and Composition
Suspension for oral administration (for children) white or almost white in color, syrup-like consistency, with a fruity odor.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: polysorbate 80 – 0.5 mg, glycerol – 630 mg, liquid maltitol – 2210 mg, sodium saccharin – 10 mg, sucralose – 10 mg, citric acid monohydrate – 20 mg, sodium citrate – 25.45 mg, xanthan gum – 37.5 mg, sodium chloride – 5.5 mg, domiphen bromide – 0.5 mg, tutti-frutti flavor – 12.5 mg, purified water – up to 5 ml.
100 ml – polyethylene terephthalate bottles (1) in a set with a dosing syringe – cardboard packs.
150 ml – polyethylene terephthalate bottles (1) in a set with a dosing syringe – cardboard packs.
200 ml – polyethylene terephthalate bottles (1) in a set with a dosing syringe – cardboard packs.
Capsules 200 mg: 10, 20, 30, 40 or 50 pcs.
Capsules 400 mg: 10, 20, 30, 40 or 50 pcs.
Marketing Authorization Holder
Pharmstandard-Ufimsky Vitaminny Zavod OJSC (Russia)
Manufactured By
Pharmstandard-Lexredstva OJSC (Russia)
Dosage Forms
|
Ibuprofen ExtraCap® | Capsules 200 mg: 10, 20, 30, 40 or 50 pcs. |
| Capsules 400 mg: 10, 20, 30, 40 or 50 pcs. |
Dosage Form, Packaging, and Composition
Capsules oval with a red translucent gelatin shell, containing a clear liquid from colorless to light pink.
| 1 caps. | |
| Ibuprofen | 200 mg |
Excipients: macrogol 600, potassium hydroxide, purified water.
Capsule shell gelatin, liquid sorbitol (non-crystallizing), purified water, dye Ponceau 4R (E124).
10 pcs. – contour cell pack (1) – cardboard packs.
10 pcs. – contour cell pack (2) – cardboard packs.
10 pcs. – contour cell pack (3) – cardboard packs.
10 pcs. – contour cell pack (4) – cardboard packs.
10 pcs. – contour cell pack (5) – cardboard packs.
10 pcs. – polypropylene bottles (1) – cardboard packs.
Capsules oval with a red translucent gelatin shell, containing a clear liquid from colorless to light pink.
| 1 caps. | |
| Ibuprofen | 400 mg |
Excipients: macrogol 600, potassium hydroxide, purified water.
Capsule shell gelatin, liquid sorbitol (non-crystallizing), purified water, dye Ponceau 4R (E124).
10 pcs. – contour cell pack (1) – cardboard packs.
10 pcs. – contour cell pack (2) – cardboard packs.
10 pcs. – contour cell pack (3) – cardboard packs.
10 pcs. – contour cell pack (4) – cardboard packs.
10 pcs. – contour cell pack (5) – cardboard packs.
10 pcs. – polypropylene bottles (1) – cardboard packs.
Rectal suppositories 60 mg: 10 units.
Marketing Authorization Holder
Patent-Pharm, JSC (Russia)
Manufactured By
Altpharm LLC (Russia)
Dosage Form
|
Ibuprofen for children | Rectal suppositories 60 mg: 10 units. |
Dosage Form, Packaging, and Composition
Rectal suppositories white or almost white in color, torpedo-shaped.
| 1 supp. | |
| Ibuprofen | 0.06 g |
Excipients: hard fat (fatty acid glycerides, Witepsol H15) – 0.74 g.
5 pcs. – contour cell packs (2) – cardboard packs.
Oral suspension for children (with orange flavor and aroma) 40 mg/1 ml: 100 g or 200 g bottle with a measuring syringe
Marketing Authorization Holder
Pharmstandard-Lexredstva OJSC (Russia)
Dosage Form
|
Ibuprofen Forte | Oral suspension for children (with orange flavor and aroma) 40 mg/1 ml: 100 g or 200 g bottle with a measuring syringe |
Dosage Form, Packaging, and Composition
Oral suspension for children from light gray or light gray with a yellowish tint to gray or gray with a yellowish tint with a characteristic orange odor.
| 5 ml | |
| Ibuprofen | 200 mg |
Excipients: liquid maltitol, glycerol (glycerin) (E422), sodium citrate dihydrate, xanthan gum (E415), citric acid monohydrate, orange flavor, sodium saccharin dihydrate (E954), sodium chloride, domiphen bromide, polysorbate 80, purified water.
100 g (80 ml) – dark glass bottles (1) in a set with a measuring syringe – cardboard packs.
200 g (160 ml) – dark glass bottles (1) in a set with a measuring syringe – cardboard packs.
Oral suspension for children (with strawberry flavor and aroma) 40 mg/1 ml: 100 g or 200 g bottle with a measuring syringe
Marketing Authorization Holder
Pharmstandard-Lexredstva OJSC (Russia)
Dosage Form
|
Ibuprofen Forte | Oral suspension for children (with strawberry flavor and aroma) 40 mg/1 ml: 100 g or 200 g bottle with a measuring syringe |
Dosage Form, Packaging, and Composition
Oral suspension for children
From light gray or light gray with a yellowish tint to gray or gray with a yellowish tint with a characteristic strawberry odor.
| 5 ml | |
| Ibuprofen | 200 mg |
Excipients: maltitol liquid, glycerol (glycerin) (E422), sodium citrate dihydrate, xanthan gum (E415), citric acid monohydrate, strawberry flavor, sodium saccharin dihydrate (E954), sodium chloride, domiphen bromide, polysorbate 80, purified water.
100 g (80 ml) – dark glass bottles (1) complete with a measuring syringe – cardboard packs.
200 g (160 ml) – dark glass bottles (1) complete with a measuring syringe – cardboard packs.
Capsules 200 mg: 2, 4, 6, 7, 8, 10, 12, 14, 16, 18, 20, 21, 28, 30, 35, 40, 42, 49, 50, 56, 60, 63, 70, 80, 84, 90, 98, 100, 112, 126 or 140 pcs.
Marketing Authorization Holder
Medisorb, JSC (Russia)
Dosage Form
|
Ibuprofen Medisorb | Capsules 200 mg: 2, 4, 6, 7, 8, 10, 12, 14, 16, 18, 20, 21, 28, 30, 35, 40, 42, 49, 50, 56, 60, 63, 70, 80, 84, 90, 98, 100, 112, 126 or 140 pcs. |
Dosage Form, Packaging, and Composition
Capsules hard gelatin, size No. 1, with a white body and a green cap; capsule contents – powder white or white with a yellowish tint.
| 1 caps. | |
| Ibuprofen | 200 mg |
Excipients: croscarmellose sodium, talc, colloidal silicon dioxide (aerosil) (A-380), magnesium stearate.
Composition of hard gelatin capsules “Coni Snap” No. 1 gelatin, titanium dioxide, yellow iron oxide dye, indigo carmine.
2 pcs. – blister packs (1) – cardboard packs.
2 pcs. – blister packs (2) – cardboard packs.
2 pcs. – blister packs (3) – cardboard packs.
2 pcs. – blister packs (4) – cardboard packs.
2 pcs. – blister packs (5) – cardboard packs.
2 pcs. – blister packs (6) – cardboard packs.
2 pcs. – blister packs (7) – cardboard packs.
2 pcs. – blister packs (8) – cardboard packs.
2 pcs. – blister packs (9) – cardboard packs.
2 pcs. – blister packs (10) – cardboard packs.
7 pcs. – blister packs (1) – cardboard packs.
7 pcs. – blister packs (2) – cardboard packs.
7 pcs. – blister packs (3) – cardboard packs.
7 pcs. – blister packs (4) – cardboard packs.
7 pcs. – blister packs (5) – cardboard packs.
7 pcs. – blister packs (6) – cardboard packs.
7 pcs. – blister packs (7) – cardboard packs.
7 pcs. – blister packs (8) – cardboard packs.
7 pcs. – blister packs (9) – cardboard packs.
7 pcs. – blister packs (10) – cardboard packs.
10 pcs. – blister packs (1) – cardboard packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (3) – cardboard packs.
10 pcs. – blister packs (4) – cardboard packs.
10 pcs. – blister packs (5) – cardboard packs.
10 pcs. – blister packs (6) – cardboard packs.
10 pcs. – blister packs (7) – cardboard packs.
10 pcs. – blister packs (8) – cardboard packs.
10 pcs. – blister packs (9) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
14 pcs. – blister packs (1) – cardboard packs.
14 pcs. – blister packs (2) – cardboard packs.
14 pcs. – blister packs (3) – cardboard packs.
14 pcs. – blister packs (4) – cardboard packs.
14 pcs. – blister packs (5) – cardboard packs.
14 pcs. – blister packs (6) – cardboard packs.
14 pcs. – blister packs (7) – cardboard packs.
14 pcs. – blister packs (8) – cardboard packs.
14 pcs. – blister packs (9) – cardboard packs.
14 pcs. – blister packs (10) – cardboard packs.
Rectal suppositories [for children] 60 mg: 5 or 10 pcs.
Marketing Authorization Holder
Pharmasintez, JSC (Russia)
Dosage Form
|
Ibuprofen Pharmasyntez | Rectal suppositories [for children] 60 mg: 5 or 10 pcs. |
Dosage Form, Packaging, and Composition
Rectal suppositories [for children] white or almost white, torpedo-shaped; the suppository section should not contain inclusions; a longitudinal section may have an air core or a funnel-shaped depression.
| 1 supp. | |
| Ibuprofen | 60 mg |
Excipients: hard fat 1 N-15 – 258 mg, hard fat 2 W-45 – 258 mg.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
Film-coated tablets, 200 mg: 2, 4, 5, 6, 8, 10, 12, 15, 16, 18, 20, 24, 25, 30, 36, 48, 50, 96 or 100 pcs.
Film-coated tablets, 400 mg: 2, 4, 5, 6, 8, 10, 12, 15, 16, 18, 20, 24, 25, 30, 36, 48, 50, 96 or 100 pcs.
Marketing Authorization Holder
Pharmasintez, JSC (Russia)
Dosage Forms
|
Ibuprofen Pharmasyntez | Film-coated tablets, 200 mg: 2, 4, 5, 6, 8, 10, 12, 15, 16, 18, 20, 24, 25, 30, 36, 48, 50, 96 or 100 pcs. |
| Film-coated tablets, 400 mg: 2, 4, 5, 6, 8, 10, 12, 15, 16, 18, 20, 24, 25, 30, 36, 48, 50, 96 or 100 pcs. |
Dosage Form, Packaging, and Composition
Film-coated tablets white, round, biconvex; the core on the cross-section is white or almost white.
| 1 tab. | |
| Ibuprofen | 200 mg |
Excipients: sodium carboxymethyl starch – 9 mg, pregelatinized starch – 35 mg, colloidal silicon dioxide – 3 mg, magnesium stearate – 3.25 mg, povidone K90 – 3.5 mg, talc – 6.25 mg, microcrystalline cellulose 101 – 65 mg.
Film coating composition hypromellose E6 – 5.1 mg, titanium dioxide – 1.65 mg, polysorbate 80 – 0.075 mg, macrogol 6000 – 0.675 mg.
2 pcs. – contour cell packs (1) – cardboard packs.
2 pcs. – contour cell packs (2) – cardboard packs.
2 pcs. – contour cell packs (3) – cardboard packs.
2 pcs. – contour cell packs (4) – cardboard packs.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (3) – cardboard packs.
5 pcs. – contour cell packs (4) – cardboard packs.
5 pcs. – contour cell packs (5) – cardboard packs.
5 pcs. – contour cell packs (10) – cardboard packs.
6 pcs. – contour cell packs (1) – cardboard packs.
6 pcs. – contour cell packs (2) – cardboard packs.
6 pcs. – contour cell packs (3) – cardboard packs.
6 pcs. – contour cell packs (4) – cardboard packs.
6 pcs. – contour cell packs (5) – cardboard packs.
8 pcs. – contour cell packs (1) – cardboard packs.
8 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
12 pcs. – contour cell packs (1) – cardboard packs.
12 pcs. – contour cell packs (2) – cardboard packs.
12 pcs. – contour cell packs (3) – cardboard packs.
12 pcs. – contour cell packs (4) – cardboard packs.
12 pcs. – contour cell packs (8) – cardboard packs.
Film-coated tablets white, oval, biconvex; the core on the cross-section is white or almost white.
| 1 tab. | |
| Ibuprofen | 400 mg |
Excipients: sodium carboxymethyl starch – 18 mg, pregelatinized starch – 70 mg, colloidal silicon dioxide – 6 mg, magnesium stearate – 6.5 mg, povidone K90 – 7 mg, talc – 12.5 mg, microcrystalline cellulose 101 – 130 mg.
Film coating composition hypromellose E6 – 10.2 mg, titanium dioxide – 3.3 mg, polysorbate 80 – 0.15 mg, macrogol 6000 – 1.35 mg.
2 pcs. – contour cell packs (1) – cardboard packs.
2 pcs. – contour cell packs (2) – cardboard packs.
2 pcs. – contour cell packs (3) – cardboard packs.
2 pcs. – contour cell packs (4) – cardboard packs.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (3) – cardboard packs.
5 pcs. – contour cell packs (4) – cardboard packs.
5 pcs. – contour cell packs (5) – cardboard packs.
5 pcs. – contour cell packs (10) – cardboard packs.
6 pcs. – contour cell packs (1) – cardboard packs.
6 pcs. – contour cell packs (2) – cardboard packs.
6 pcs. – contour cell packs (3) – cardboard packs.
6 pcs. – contour cell packs (4) – cardboard packs.
6 pcs. – contour cell packs (5) – cardboard packs.
8 pcs. – contour cell packs (1) – cardboard packs.
8 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
12 pcs. – contour cell packs (1) – cardboard packs.
12 pcs. – contour cell packs (2) – cardboard packs.
12 pcs. – contour cell packs (3) – cardboard packs.
12 pcs. – contour cell packs (4) – cardboard packs.
12 pcs. – contour cell packs (8) – cardboard packs.
Oral suspension (with cola flavor) 100 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle
Oral suspension (with orange flavor) 100 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle
Oral suspension (with cola flavor) 200 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle
Oral suspension (with orange flavor) 200 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle
Marketing Authorization Holder
Pharmtekhnologiya LLC (Republic of Belarus)
Dosage Forms
|
Ibuprofen PhT | Oral suspension (with cola flavor) 100 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle |
| Oral suspension (with orange flavor) 100 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle | ||
| Oral suspension (with cola flavor) 200 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle | ||
| Oral suspension (with orange flavor) 200 mg/5 ml: 60 ml, 100 ml, 150 ml, or 200 ml bottle |
Dosage Form, Packaging, and Composition
Oral suspension white or almost white, with a cola odor; separation of the suspension is allowed, which is eliminated upon shaking.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: macrogolglycerol hydroxystearate, xanthan gum, glycerol, sodium benzoate (E211), sodium dihydrogen phosphate dihydrate, citric acid monohydrate, sodium saccharin, maltitol liquid (E965), cola flavor, concentrated sodium hydroxide solution or diluted phosphoric acid (to adjust pH to 3.2-4.5), purified water.
60 ml – bottles – cardboard packs complete with a dosing syringe.
100 ml – bottles – cardboard packs complete with a dosing syringe.
150 ml – bottles – cardboard packs complete with a dosing syringe.
200 ml – bottles – cardboard packs complete with a dosing syringe.
Oral suspension white or almost white, with an orange odor; separation of the suspension is allowed, which is eliminated upon shaking.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: macrogolglycerol hydroxystearate, xanthan gum, glycerol, sodium benzoate (E211), sodium dihydrogen phosphate dihydrate, citric acid monohydrate, sodium saccharin, maltitol liquid (E965), orange flavor, concentrated sodium hydroxide solution or diluted phosphoric acid (to adjust pH to 3.2-4.5), purified water.
60 ml – bottles – cardboard packs complete with a dosing syringe.
100 ml – bottles – cardboard packs complete with a dosing syringe.
150 ml – bottles – cardboard packs complete with a dosing syringe.
200 ml – bottles – cardboard packs complete with a dosing syringe.
Oral suspension white or almost white, with a cola odor; separation of the suspension is allowed, which is eliminated upon shaking.
| 5 ml | |
| Ibuprofen | 200 mg |
Excipients: macrogolglycerol hydroxystearate, xanthan gum, glycerol, sodium benzoate (E211), sodium dihydrogen phosphate dihydrate, citric acid monohydrate, sodium saccharin, maltitol liquid (E965), cola flavor, concentrated sodium hydroxide solution or diluted phosphoric acid (to adjust pH to 3.2-4.5), purified water.
60 ml – bottles – cardboard packs complete with a dosing syringe.
100 ml – bottles – cardboard packs complete with a dosing syringe.
150 ml – bottles – cardboard packs complete with a dosing syringe.
200 ml – bottles – cardboard packs complete with a dosing syringe.
Oral suspension white or almost white, with an orange odor; separation of the suspension is allowed, which is eliminated upon shaking.
| 5 ml | |
| Ibuprofen | 200 mg |
Excipients: macrogolglycerol hydroxystearate, xanthan gum, glycerol, sodium benzoate (E211), sodium dihydrogen phosphate dihydrate, citric acid monohydrate, sodium saccharin, maltitol liquid (E965), orange flavor, concentrated sodium hydroxide solution or diluted phosphoric acid (to adjust pH to 3.2-4.5), purified water.
60 ml – bottles – cardboard packs complete with a dosing syringe.
100 ml – bottles – cardboard packs complete with a dosing syringe.
150 ml – bottles – cardboard packs complete with a dosing syringe.
200 ml – bottles – cardboard packs complete with a dosing syringe.
Film-coated tablets 200 mg: 10, 20, 30 or 50 pcs.
Film-coated tablets 400 mg: 10, 20, 30 or 50 pcs.
Marketing Authorization Holder
Obnovlenie Pfc, JSC (Russia)
Dosage Forms
|
Ibuprofen Reneval | Film-coated tablets 200 mg: 10, 20, 30 or 50 pcs. |
| Film-coated tablets 400 mg: 10, 20, 30 or 50 pcs. |
Dosage Form, Packaging, and Composition
Film-coated tablets white or almost white, round biconvex; surface roughness is allowed; the core on the cross-section is white or almost white.
| 1 tab. | |
| Ibuprofen | 200 mg |
Excipients: microcrystalline cellulose, corn starch, sodium carboxymethyl starch, colloidal silicon dioxide (aerosil), magnesium stearate.
Coating composition Opadry® 85F48105 white [polyvinyl alcohol (E1203), macrogol 3350, talc, titanium dioxide (E171)].
10 pcs. – contour blister pack (1, 2, 3 or 5) – cardboard packs with an insert.
Film-coated tablets white or almost white with a score, oval biconvex; surface roughness is allowed; the core on the cross-section is white or almost white.
| 1 tab. | |
| Ibuprofen | 400 mg |
Excipients: microcrystalline cellulose, corn starch, sodium carboxymethyl starch, colloidal silicon dioxide (aerosil), magnesium stearate.
Coating composition Opadry® 85F48105 white [polyvinyl alcohol (E1203), macrogol 3350, talc, titanium dioxide (E171)].
10 pcs. – contour blister pack (1, 2, 3 or 5) – cardboard packs with an insert.
Film-coated tablets 200 mg: 20 or 50 pcs.
Marketing Authorization Holder
Sandoz, d.d. (Slovenia)
Substance Manufacturer
BASF CORPORATION (USA)
Manufactured By
SANDOZ ILAC SANAYI VE TICARET, A.S. (Turkey)
Dosage Form
|
Ibuprofen Sandoz | Film-coated tablets 200 mg: 20 or 50 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – blisters (2) – cardboard packs.
10 pcs. – blisters (5) – cardboard packs.
Film-coated tablets 400 mg: 20 or 50 pcs.
Marketing Authorization Holder
Sandoz, d.d. (Slovenia)
Substance Manufacturer
BASF CORPORATION (USA)
Manufactured By
SANDOZ ILAC SANAYI VE TICARET, A.S. (Turkey)
Dosage Form
|
Ibuprofen Sandoz | Film-coated tablets 400 mg: 20 or 50 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 400 mg |
10 pcs. – blisters (2) – cardboard packs.
10 pcs. – blisters (5) – cardboard packs.
Film-coated tablets 400 mg: 20 or 50 pcs.
Marketing Authorization Holder
Sandoz, d.d. (Slovenia)
Substance Manufacturer
BASF CORPORATION (USA)
Manufactured By
SANDOZ ILAC SANAYI VE TICARET, A.S. (Turkey)
Labeled By
SALUTAS PHARMA, GmbH (Germany)
Dosage Form
|
Ibuprofen Sandoz | Film-coated tablets 400 mg: 20 or 50 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 400 mg |
10 pcs. – blisters (2) – cardboard packs.
10 pcs. – blisters (5) – cardboard packs.
Film-coated tablets 200 mg: 20 or 50 pcs.
Marketing Authorization Holder
Sandoz, d.d. (Slovenia)
Substance Manufacturer
BASF CORPORATION (USA)
Manufactured By
SANDOZ ILAC SANAYI VE TICARET, A.S. (Turkey)
Labeled By
SALUTAS PHARMA, GmbH (Germany)
Dosage Form
|
Ibuprofen Sandoz | Film-coated tablets 200 mg: 20 or 50 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
10 pcs. – blisters (2) – cardboard packs.
10 pcs. – blisters (5) – cardboard packs.
Film-coated tablets, 200 mg: from 5 to 140 pcs.
Film-coated tablets, 400 mg: from 5 to 140 pcs.
Marketing Authorization Holder
Velpharm, LLC (Russia)
Manufactured By
Velpharm, LLC (Russia)
Or
Marbiopharm, JSC (Russia)
Or
Uralbiopharm, JSC (Russia)
Or
Velpharm-M, LLC (Russia)
Dosage Forms
|
Ibuprofen Velpharm | Film-coated tablets, 200 mg: from 5 to 140 pcs. |
| Film-coated tablets, 400 mg: from 5 to 140 pcs. |
Dosage Form, Packaging, and Composition
Film-coated tablets white or almost white, round, biconvex; a cross-section shows one layer of white or almost white color.
| 1 tab. | |
| Ibuprofen | 200 mg |
Excipients: povidone K90 (Kollidon 90F), microcrystalline cellulose (type 102), talc, crospovidone (Kollidon CL, Kollidon CL-M), calcium stearate, colloidal silicon dioxide (aerosil), corn starch.
Shell composition [dry mix for film coating containing hypromellose, titanium dioxide, macrogol or hypromellose (hydroxypropyl methylcellulose), titanium dioxide, macrogol 6000 (polyethylene glycol 6000, polyethylene oxide 6000)].
From 5 to 14 pcs. – contour cell packs (from 1 to 10 pcs.) – cardboard packs.
From 5 to 60 pcs. – jars (1) – cardboard packs.
Film-coated tablets white or almost white, oval, biconvex; a cross-section shows one layer of white or almost white color.
| 1 tab. | |
| Ibuprofen | 400 mg |
Excipients: povidone K90 (Kollidon 90F), microcrystalline cellulose (type 102), talc, crospovidone (Kollidon CL, Kollidon CL-M), calcium stearate, colloidal silicon dioxide (aerosil), corn starch.
Shell composition [dry mix for film coating containing hypromellose, titanium dioxide, macrogol or hypromellose (hydroxypropyl methylcellulose), titanium dioxide, macrogol 6000 (polyethylene glycol 6000, polyethylene oxide 6000)].
From 5 to 14 pcs. – contour cell packs (from 1 to 10 pcs.) – cardboard packs.
From 5 to 60 pcs. – jars (1) – cardboard packs.
Film-coated tablets 200 mg: 14 pcs.
Film-coated tablets 400 mg: 20 pcs.
Marketing Authorization Holder
Viva Farm, LLP (Kazakhstan)
Dosage Forms
|
Ibuprofen Viva Farm | Film-coated tablets 200 mg: 14 pcs. |
| Film-coated tablets 400 mg: 20 pcs. |
Dosage Form, Packaging, and Composition
| Film-coated tablets | 1 tab. |
| Ibuprofen | 200 mg |
7 pcs. – contour cell packs (2) – cardboard packs.
| Film-coated tablets | 1 tab. |
| Ibuprofen | 400 mg |
10 pcs. – contour cell packs (2) – cardboard packs.
Oral suspension (for children) 100 mg/5 ml: 100 ml, 150 ml, or 200 ml bottle with a dosing syringe
Marketing Authorization Holder
Vetprom, AD (Bulgaria)
Dosage Form
|
Ibuprofen VP | Oral suspension (for children) 100 mg/5 ml: 100 ml, 150 ml, or 200 ml bottle with a dosing syringe |
Dosage Form, Packaging, and Composition
Oral suspension [for children] white or almost white, syrup-like consistency, with a fruity smell.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: polysorbate 80 – 0.5 mg, glycerol – 630 mg, liquid maltitol – 2210 mg, sodium saccharin – 10 mg, citric acid monohydrate – 20 mg, sodium citrate – 25.45 mg, xanthan gum – 37.5 mg, sodium chloride – 5.5 mg, domiphen bromide – 0.5 mg, tutti-frutti flavor – 12.5 mg, purified water – up to 5 ml.
100 ml – polyethylene terephthalate bottles (1) with a dosing syringe – cardboard packs.
150 ml – polyethylene terephthalate bottles (1) with a dosing syringe – cardboard packs.
200 ml – polyethylene terephthalate bottles (1) with a dosing syringe – cardboard packs.
Oral suspension (for children, with orange aroma) 100 mg/5 ml: 100 ml bottle with a dosing spoon or a measuring syringe
Oral suspension for children (with strawberry aroma) 100 mg/5 ml: 100 ml bottle with a dosing spoon or a measuring syringe
Oral suspension (for children, with apple aroma) 100 mg/5 ml: 100 ml bottle with a dosing spoon or a measuring syringe
Oral suspension (for children, pear-flavored) 100 mg/5 ml: 100 ml bottle with a dosing spoon or measuring syringe
Marketing Authorization Holder
Sintez PJSC (Russia)
Dosage Forms
|
Ibuprofen-Akos | Oral suspension (for children, with orange aroma) 100 mg/5 ml: 100 ml bottle with a dosing spoon or a measuring syringe |
| Oral suspension for children (with strawberry aroma) 100 mg/5 ml: 100 ml bottle with a dosing spoon or a measuring syringe | ||
| Oral suspension (for children, with apple aroma) 100 mg/5 ml: 100 ml bottle with a dosing spoon or a measuring syringe | ||
| Oral suspension (for children, pear-flavored) 100 mg/5 ml: 100 ml bottle with a dosing spoon or measuring syringe |
Dosage Form, Packaging, and Composition
Oral suspension for children (with orange aroma) from white to white with a grayish or grayish-yellowish tint, with a characteristic orange smell.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: polysorbate-80 (Tween-80), glycerol (glycerin), maltitol (liquid maltitol), sodium saccharin dihydrate, citric acid monohydrate, sodium citrate dihydrate (sodium citrate 2-hydrate), xanthan gum (xanthan resin), sodium chloride, domiphen bromide, orange flavor (food flavor “Orange”), purified water.
100 ml – orange glass bottles (1) with a dosing spoon – cardboard packs.
100 ml – orange glass bottles (1) with a measuring syringe – cardboard packs.
Oral suspension for children (with strawberry aroma) from white to white with a grayish or grayish-yellowish tint, with a characteristic strawberry smell.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: polysorbate-80 (Tween-80), glycerol (glycerin), maltitol (liquid maltitol), sodium saccharin dihydrate, citric acid monohydrate, sodium citrate dihydrate (sodium citrate 2-hydrate), xanthan gum (xanthan resin), sodium chloride, domiphen bromide, strawberry flavor (food flavor “Strawberry”), purified water.
100 ml – orange glass bottles (1) with a dosing spoon – cardboard packs.
100 ml – orange glass bottles (1) with a measuring syringe – cardboard packs.
Oral suspension for children (with apple aroma) from white to white with a grayish or grayish-yellowish tint, with a characteristic apple smell.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: polysorbate-80 (Tween-80), glycerol (glycerin), maltitol (liquid maltitol), sodium saccharin dihydrate, citric acid monohydrate, sodium citrate dihydrate (sodium citrate 2-hydrate), xanthan gum (xanthan resin), sodium chloride, domiphen bromide, apple flavor (food flavor “Apple”), purified water.
100 ml – orange glass bottles (1) with a dosing spoon – cardboard packs.
100 ml – orange glass bottles (1) with a measuring syringe – cardboard packs.
Oral suspension for children (with pear aroma) from white to white with a grayish or grayish-yellowish tint, with a characteristic pear smell.
| 5 ml | |
| Ibuprofen | 100 mg |
Excipients: polysorbate-80 (Tween-80), glycerol (glycerin), maltitol (liquid maltitol), sodium saccharin dihydrate, citric acid monohydrate, sodium citrate dihydrate (sodium citrate 2-hydrate), xanthan gum (xanthan resin), sodium chloride, domiphen bromide, pear flavor (food flavor “Pear”), purified water.
100 ml – orange glass bottles (1) with a dosing spoon – cardboard packs.
100 ml – orange glass bottles (1) with a measuring syringe – cardboard packs.
Film-coated tablets 200 mg: 20, 50, or 100 pcs.
Film-coated tablets 400 mg: 20, 50, or 100 pcs.
Marketing Authorization Holder
Sintez PJSC (Russia)
Dosage Forms
|
Ibuprofen-Akos | Film-coated tablets 200 mg: 20, 50, or 100 pcs. |
| Film-coated tablets 400 mg: 20, 50, or 100 pcs. |
Dosage Form, Packaging, and Composition
Film-coated tablets white or almost white, round biconvex.
| 1 tab. | |
| Ibuprofen | 200 mg |
Excipients: povidone (Kollidon 90F), microcrystalline cellulose, talc, crospovidone (Kollidon CL, Kollidon CL-F), calcium stearate, colloidal silicon dioxide (aerosil), corn starch.
Shell composition hypromellose (hydroxypropyl methylcellulose), titanium dioxide, macrogol 4000 (polyethylene oxide 4000, polyethylene glycol 4000).
10 pcs. – contour cell pack (2) – cardboard packs.
10 pcs. – contour cell pack (5) – cardboard packs.
10 pcs. – contour cell pack (10) – cardboard packs.
Film-coated tablets white or almost white, biconvex oval; a cross-section shows a layer of white or almost white color.
| 1 tab. | |
| Ibuprofen | 400 mg |
Excipients: povidone (Kollidon 90F), microcrystalline cellulose, talc, crospovidone (Kollidon CL, Kollidon CL-F), calcium stearate, colloidal silicon dioxide (aerosil), corn starch.
Shell composition hypromellose (hydroxypropyl methylcellulose), titanium dioxide, macrogol 4000 (polyethylene oxide 4000, polyethylene glycol 4000).
10 pcs. – contour cell pack (2) – cardboard packs.
10 pcs. – contour cell pack (5) – cardboard packs.
10 pcs. – contour cell pack (10) – cardboard packs.
Rectal suppositories (for children) 60 mg: 5 or 10 pcs.
Marketing Authorization Holder
Medana Pharma, SA (Poland)
Manufactured By
Apipol-Farma Sp. z o.o. (Poland)
Dosage Form
|
Ibuprofen-Akrikhin | Rectal suppositories (for children) 60 mg: 5 or 10 pcs. |
Dosage Form, Packaging, and Composition
Rectal suppositories for children white or almost white, torpedo-shaped.
| 1 supp. | |
| Ibuprofen | 60 mg |
Excipients: hard fat 1 (Witepsol H15) – 258 mg, hard fat 2 (Witepsol W45) – 258 mg.
5 pcs. – blisters (1) – cardboard packs.
5 pcs. – blisters (2) – cardboard packs.
Rectal suppositories (for children) 60 mg: 5 or 10 pcs.
Marketing Authorization Holder
Pharmasintez, JSC (Russia)
Dosage Form
|
Ibuprofen-FS | Rectal suppositories (for children) 60 mg: 5 or 10 pcs. |
Dosage Form, Packaging, and Composition
Rectal suppositories for children white or almost white, torpedo-shaped; the suppository section should not contain inclusions; a longitudinal section may have an air core or a funnel-shaped depression.
| 1 supp. | |
| Ibuprofen | 60 mg |
Excipients: hard fat 1 Witepsol H-15 – 258 mg, hard fat 2 Witepsol W-45 – 258 mg.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
Film-coated tablets, 400 mg: 10, 20, 30, or 50 pcs.
Marketing Authorization Holder
Hemofarm, A.D. (Serbia)
Manufactured By
Hemofarm, A.D. (Serbia)
Packaging and Quality Control Release
HEMOFARM, A.D. (Serbia)
Dosage Form
|
Ibuprofen-Hemofarm | Film-coated tablets, 400 mg: 10, 20, 30, or 50 pcs. |
Dosage Form, Packaging, and Composition
Film-coated tablets from white to yellowish-white in color, round, biconvex, with a score on one side; the core on the cross-section is from white to yellowish-white.
| 1 tab. | |
| Ibuprofen | 400 mg |
Excipients: microcrystalline cellulose (type PH101), sodium carboxymethyl starch (sodium starch glycolate (type A)), colloidal anhydrous silicon dioxide, stearic acid.
Film coating composition: methacrylic acid and ethyl acrylate copolymer (1:1), talc, titanium dioxide, polysorbate 80.
10 pcs. – blisters (1) – cardboard packs.
10 pcs. – blisters (2) – cardboard packs.
10 pcs. – blisters (3) – cardboard packs.
10 pcs. – blisters (5) – cardboard packs.
Capsules 200 mg: 10, 20, or 30 pcs.
Marketing Authorization Holder
Vertex, JSC (Russia)
Dosage Form
|
Ibuprofen-Vertex | Capsules 200 mg: 10, 20, or 30 pcs. |
Dosage Form, Packaging, and Composition
Capsules white in color, hard, gelatin, size №0; capsule contents – a powder of white or almost white color.
| 1 caps. | |
| Ibuprofen | 200 mg |
Excipients: sodium citrate dihydrate, croscarmellose sodium, colloidal silicon dioxide, talc, magnesium stearate, sodium lauryl sulfate.
Hard gelatin capsulesCap body composition: titanium dioxide, gelatin.
Cap composition titanium dioxide, gelatin.
10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – jars (1) – cardboard packs.
20 pcs. – jars (1) – cardboard packs.
![Ibuprofen [Tablets, Capsules, Suppositories, Suspension] 1](https://www.medixlife.com/wp-content/uploads/Medixlife_favi_512.png "Ibuprofen [Tablets, Capsules, Suppositories, Suspension] 2")