NovoPanthen (Ointment, Aerosol) Instructions for Use

ATC Code

D03AX03 (Dexpanthenol)

Active Substance

Dexpanthenol (Rec.INN registered by WHO)

Clinical-Pharmacological Group

A drug improving trophism and tissue regeneration, for external use

Pharmacotherapeutic Group

Drugs for the treatment of wounds and ulcers; drugs promoting normal scarring; other drugs promoting normal scarring

Pharmacological Action

A tissue regeneration stimulator, belongs to the B vitamins. Dexpanthenol is a precursor of pantothenic acid. In the body, it is converted into pantothenic acid, which is a constituent part of coenzyme A and participates in acetylation processes, carbohydrate and fat metabolism, and in the synthesis of acetylcholine, corticosteroids, and porphyrins; it stimulates the regeneration of the skin and mucous membranes, normalizes cellular metabolism, accelerates mitosis, and increases the strength of collagen fibers. It has a regenerating, metabolic, and weak anti-inflammatory effect.

Data obtained from animal experiments indicate an increase in fibroblast proliferation and the presence of a regenerating effect. When applied externally and locally, Dexpanthenol is able to compensate for the increased need of damaged skin or mucous membranes for pantothenic acid.

Pharmacokinetics

Dexpanthenol is quickly absorbed by the skin and converted into pantothenic acid.

It binds to blood plasma proteins (mainly to albumin and β-globulin).

Pantothenic acid is not metabolized in the body and is excreted unchanged.

Indications

Violation of the integrity of the skin: healing of burns (including sunburns), minor skin injuries (including abrasions, cuts, cracks); prevention and treatment of dry skin, including as a consequence of dermatitis of various origins; daily care of skin areas most exposed to external factors (face, hands); care of the mammary glands during lactation (cracks and redness of the nipples of the mammary gland); care for infants and babies (diaper rash, diaper dermatitis).

ICD codes

Dosage Regimen

Apply a thin layer of the ointment or spray to the affected skin areas.

Gently rub in the preparation until fully absorbed.

For minor wounds, cuts, and abrasions, apply 2-3 times daily.

For sunburns and thermal burns, apply 3-4 times daily or as needed for symptomatic relief.

For the prevention and treatment of dry skin, apply 1-2 times daily to clean, dry skin.

For daily skin care of exposed areas like hands and face, apply once daily.

For cracked nipples during lactation, apply after each feeding; thoroughly remove any residue before the next feeding.

For diaper rash and diaper dermatitis in infants, apply with each diaper change to clean, dry skin.

When using the aerosol, hold the container upright and spray from a distance of approximately 10-15 cm.

The frequency of application depends on the severity of the condition and the indication.

Continue treatment until the skin condition is fully resolved.

If symptoms persist or worsen after 7-10 days, discontinue use and consult a physician.

Avoid contact with eyes and mucous membranes. Do not apply to heavily exuding or deeply infected wounds without medical supervision.

Adverse Reactions

In very rare cases, allergic reactions are possible.

Contraindications

Hypersensitivity to dexpanthenol.

Use in Pregnancy and Lactation

Can be used during pregnancy and breastfeeding.

Storage Conditions

Store at 15°C (59°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.