Prohepar^® (Tablets) Instructions for Use

Marketing Authorization Holder

Time Trade Handelsgesellschaft, mbH (Germany)

Manufactured By

NORDMARK ARZNEIMITTEL, GmbH & Co.KG (Germany)

ATC Code

A05BA (Drugs for the treatment of liver diseases)

Dosage Form

Prohepar^®

Film-coated tablets: 20, 50, or 100 pcs.

Dosage Form, Packaging, and Composition

*Film-coated tablets*	1 tab.
Inositol	25 mg
Cyanocobalamin	Not less than 1.5 mcg
Liver extract KPC N (liver hydrolysate) 70 mg, containing
Choline bitartrate	100 mg
Cysteine	16.57 mg
Cysteine hydrochloride 21.5 mg,

50 pcs. – dark glass bottles (1) – cardboard packs.
20 pcs. – dark glass bottles (1) – cardboard packs.
100 pcs. – dark glass bottles (1) – cardboard packs.

Clinical-Pharmacological Group

Hepatoprotective agent

Pharmacotherapeutic Group

Hepatoprotective agent

Pharmacological Action

The drug Prohepar^® helps to preserve and restore the structure of hepatocytes, inhibits the formation of connective tissue in the liver, and promotes the regeneration of the part of the parenchyma that has been destroyed.

The drug Prohepar^® also helps to improve local blood flow in the liver tissue, increases diuresis, and improves the functional parameters of the liver.

Indications

Complex therapy for chronic hepatitis;
Fatty liver dystrophy of various origins;
Toxic hepatitis, including alcoholic;
Liver cirrhosis;
Hepatopathies of various origins;
Drug intoxication;
Radiation sickness;
During courses of cytostatic therapy;
Psoriasis.

ICD codes

Open the list of ICD codes

ICD-10 code	Indication
B18.1	Chronic viral hepatitis B without delta-agent
B18.2	Chronic viral hepatitis C
K70	Alcoholic liver disease
K71	Toxic liver disease
K73	Chronic hepatitis, not elsewhere classified
K74	Fibrosis and cirrhosis of liver
K76.0	Fatty (change of) liver, not elsewhere classified
L40	Psoriasis
T66	Unspecified effects of radiation (radiation sickness)
Y43.1	Antineoplastic antimetabolites
Y43.3	Other antineoplastic drugs

ICD-11 code	Indication
1E51.0Z	Chronic hepatitis B, unspecified
1E51.1	Chronic viral hepatitis C
4A85.00	Drug hypersensitivity-induced liver disease
8E61.0	Radiation-induced brain injury
8E61.1	Radiation-induced spinal cord injury
DB92.0	Non-alcoholic fatty liver disease without steatohepatitis
DB92.Y	Other specified non-alcoholic fatty liver disease
DB92.Z	Non-alcoholic fatty liver disease, unspecified
DB93	Fibrosis or cirrhosis of liver
DB94.Z	Alcoholic liver disease, unspecified
DB95.Z	Drug-induced or toxic liver disease, unspecified
DB97.2	Chronic hepatitis, not elsewhere classified
EA90.Z	Psoriasis, unspecified
NF00	Exposure to radiation, not elsewhere classified
PL00	Drugs, medicaments or biological substances causing injury or harm in therapeutic use

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Take 1 to 2 tabletsthree times daily unless otherwise directed by a physician.

Swallow tablets whole; do not chew or crush.

Take with a sufficient amount of liquid.

Adhere to a daily dosing schedule for the duration of therapy.

The treatment course is individual and must be determined by a healthcare professional based on the specific liver condition and patient response.

For chronic conditions such as hepatitis, cirrhosis, or fatty liver disease, anticipate long-term administration.

During cytostatic therapy or for drug intoxication, follow the dosing schedule for the duration of the concomitant treatment.

Duration of use for psoriasis is determined by the treating physician.

Adverse Reactions

Allergic reactions are possible.

Contraindications

Childhood;
Hypersensitivity to the components of the drug.

Pediatric Use

Contraindicated in childhood.

Storage Conditions

At a temperature not exceeding 25°C (77°F), in a dry place, protected from light and out of reach of children.

Shelf Life

Shelf life – 3 years.

Dispensing Status

The drug is available without a prescription.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer