Ringer (Solution) Instructions for Use
ATC Code
B05BB01 (Electrolytes)
Active Substance
Compound solution of sodium chloride (Rec.INN registered by WHO)
Clinical-Pharmacological Group
Drug for rehydration and detoxification for parenteral use
Pharmacotherapeutic Group
Blood substitutes and perfusion solutions; solutions for intravenous administration; solutions affecting water-electrolyte balance
Pharmacological Action
A means for rehydration and detoxification, it restores the water and electrolyte composition of the blood. When used as a means for replenishing the circulating blood volume (CBV), due to its rapid exit from the bloodstream into the extravascular space, the effect lasts only for 30-40 minutes (which is why the solution is only suitable for short-term replenishment of CBV).
The main cation of the extracellular fluid, sodium, is involved in controlling water distribution, water balance, and the osmotic pressure of body fluids. It is also associated with chloride and bicarbonate in regulating the body’s acid-base balance.
The main cation of the intracellular fluid, potassium, is involved in the synthesis of carbohydrates and proteins, nerve impulse conduction, and muscle contraction.
Calcium in ionized form is necessary for the functional mechanism of blood coagulation, normal heart function, and the regulation of neuromuscular excitability.
The main extracellular anion, chloride, is closely related to sodium metabolism and is involved in regulating the body’s acid-base balance.
Pharmacokinetics
The pharmacokinetics of sodium and chloride ions are the same as those from dietary intake. They are distributed to all organs, tissues, and interstitial spaces and are excreted by the kidneys via glomerular filtration. Significant reabsorption of Na+ and Cl– ions occurs in the tubules, especially in the loop of Henle and distal tubules.
Potassium ions are freely filtered in the glomeruli but are almost completely reabsorbed in the proximal tubules (excretion is about 100%). The kidneys have a limited ability to conserve K+ concentration. Therefore, when the Na+ concentration in the distal tubules is high, the loss of K+ can be significant, and hypokalemia may develop. This justifies the presence of K+ in the composition of the product.
The homeostasis of calcium ions is well controlled by hormones and rarely requires clinical intervention with intravenous infusion of the solution.
The product is not metabolized in the body and is rapidly excreted by the kidneys (80% within 4 hours, completely excreted within 12-24 hours).
Indications
Dehydration and electrolyte imbalance (3rd and 4th-degree thermal burns), acute blood loss, correction of water-salt balance in acute diffuse peritonitis and intestinal obstruction, acute intestinal infections (severe course, inability to take oral rehydration agents), hypovolemic shock, therapeutic plasmapheresis, intestinal fistula.
ICD codes
| ICD-10 code | Indication |
| A09 | Other and unspecified gastroenteritis and colitis of infectious origin |
| E86 | Volume depletion (including dehydration, hypovolemia) |
| E87 | Other disorders of fluid, electrolyte and acid-base balance |
| K59.8 | Other specified functional intestinal disorders |
| K63.2 | Fistula of intestine |
| K65.0 | Acute peritonitis (including abscess) |
| R57.1 | Hypovolemic shock |
| R58 | Hemorrhage, not elsewhere classified |
| T30 | Burns and corrosions of unspecified body region |
| ICD-11 code | Indication |
| 1A40.Z | Infectious gastroenteritis or colitis, unspecified |
| 5C70.Z | Decrease of volume of fluid [hypovolemia], unspecified |
| 5C7Z | Other disorders of fluid, electrolyte and acid-base balance |
| DA92.0 | Fistula of small intestine |
| DB31.0 | Fistula of large intestine |
| DB32.3 | Acquired hypoganglionosis of the colon |
| DB32.Z | Colonic motility disorders, unspecified |
| DC50.0 | Primary peritonitis |
| DC50.2 | Peritoneal abscess |
| DC50.Z | Peritonitis, unspecified |
| DD90.2 | Functional heartburn |
| DD91.Y | Other specified irritable bowel syndrome or functional bowel disorders |
| DD93.Y | Other specified functional gastrointestinal disorders in infants, toddlers and school-age children |
| ME24.1 | Fistula of digestive system |
| MG27 | Hemorrhage, not elsewhere classified |
| MG40.1 | Hypovolemic shock |
| NE11 | Burn of unspecified body region |
Dosage Regimen
| The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen. |
Solution
Intravenously, by drip, at a rate of 60-80 drops/min, or by stream. The daily dose for adults is 5-20 ml/kg, which can be increased to 30-50 ml/kg if necessary. The daily dose for children is 5-10 ml/kg, the rate of administration is 30-60 drops/min; in shock, 20-30 ml/kg is initially administered. The course of treatment is 3-5 days. For therapeutic plasmapheresis, it is administered in a volume twice the volume of removed plasma (1.2-2.4 L), in case of severe hypovolemia – in combination with colloid solutions. The maximum volume of the administered solution is 3 L/day.
Adverse Reactions
Possible electrolyte imbalance, hyperhydration, allergic reactions, fever (with rapid administration), local reactions at the injection site.
Contraindications
Hypersensitivity to the components of the product; hypernatremia, hyperchloremia, hypercalcemia, hyperkalemia, acidosis, chronic heart failure NYHA functional class III-IV, pulmonary edema, cerebral edema, hypercoagulation, hypervolemia, thrombophlebitis, metabolic alkalosis, severe chronic renal failure with oligo- and anuria, concomitant therapy with corticosteroids.
With caution: arterial hypertension; cardiovascular diseases (including chronic heart failure NYHA functional class I-II), simultaneous use of cardiac glycosides, simultaneous administration with blood products due to the risk of coagulation, hepatic insufficiency; preeclampsia; peripheral edema of various origins; hyperaldosteronism and other pathologies associated with hypernatremia or hyperkalemia (mild to moderate renal failure, adrenal insufficiency, acute dehydration, extensive tissue breakdown); diseases and conditions predisposing to increased vitamin D concentration (including sarcoidosis).
Use in Pregnancy and Lactation
During pregnancy, it can be used according to indications in cases where the expected benefit to the mother outweighs the potential risk to the fetus.
If it is necessary to use during lactation, the issue of discontinuing breastfeeding should be decided.
Use in Hepatic Impairment
Use with caution in hepatic insufficiency.
Use in Renal Impairment
Contraindicated in severe chronic renal failure with oligo- and anuria. Use with caution in patients with kidney diseases.
Pediatric Use
Can be used in children according to indications in doses recommended for the respective age.
Special Precautions
During long-term therapy, it is necessary to determine laboratory parameters together with an assessment of the patient’s condition to monitor water-electrolyte balance and acid-base balance every 6 hours (depending on the infusion rate).
In case of rapid administration of a large volume of the solution, it is necessary to monitor the acid-base status and electrolyte concentrations. A decrease in blood pH leads to an increase in the K+ content in the blood serum.
The use of this product may cause fluid volume overload, congestion, and pulmonary edema. The risk of dilution is inversely proportional to the electrolyte concentration, and the risk of volume overload is directly proportional.
Due to the content of sodium ions, this product should be used with caution in patients with clinical conditions accompanied by sodium retention and edema, as well as in those receiving corticosteroids or corticotropin.
Due to the content of potassium ions, this product should be used with caution in patients with cardiovascular diseases, hyperkalemia, renal failure, and clinical conditions accompanied by potassium retention.
Due to the high content of chloride ions, long-term use of the product is not recommended.
Due to the content of calcium ions, this product should be used with caution in patients taking cardiac glycosides. ECG monitoring is necessary. The concentration of calcium in blood plasma does not always correlate with the concentration of calcium in tissues.
Drug Interactions
When combined with any other drugs, it is necessary to visually control pharmaceutical compatibility.
Concomitant use with NSAIDs, androgens, anabolic hormones, estrogens, corticotropin, mineralocorticoids, vasodilators, or ganglion blockers may increase sodium retention in the body.
Concomitant use with potassium-sparing diuretics, ACE inhibitors, angiotensin II receptor antagonists, tacrolimus, cyclosporine, and potassium preparations increases the risk of hyperkalemia.
Concomitant use with thiazide diuretics or vitamin D increases the risk of hypercalcemia.
In combination with cardiac glycosides, the likelihood of toxic effects of the latter increases.
Storage Conditions
Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.
Dispensing Status
Rx Only
Important Safety Information
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.
Medical DisclaimerBrand (or Active Substance), Marketing Authorisation Holder, Dosage Form
Solution for infusion: bottles 500 ml 1 or 10 pcs.
Marketing Authorization Holder
Hemofarm, A.D. (Serbia)
Dosage Form
 |
Ringer's solution | Solution for infusion: bottles 500 ml 1 or 10 pcs. |
Dosage Form, Packaging, and Composition
Solution for infusion transparent, colorless.
| 1 L | |
| Sodium chloride | 8.6 g |
| Calcium chloride | 330 mg |
| Potassium chloride | 300 mg, |
| Which corresponds to the content of | |
| Na+ | 147 mmol |
| Ca2+ | 2.25 mmol |
| Cl– | 155.6 mmol |
| Theoretical osmolarity 309 mOsm/L | |
Excipients: sodium hydroxide, hydrochloric acid, water for injections.
500 ml – bottles made of low-density polyethylene with a built-in dropper holder (1) – cardboard packs.
500 ml – bottles made of low-density polyethylene with a built-in dropper holder (10) – cardboard boxes.
Solution for infusion: bottles 200 or 400 ml, containers 250 or 500 ml
Marketing Authorization Holder
Biosintez, PJSC (Russia)
Dosage Form
|
Ringer's solution | Solution for infusion: bottles 200 or 400 ml, containers 250 or 500 ml |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Compound solution of sodium chloride | 100% |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
200 ml – glass bottles (1) – cardboard packs.
400 ml – glass bottles (1) – cardboard packs.
200 ml – glass bottles (24) – cardboard boxes.
200 ml – glass bottles (28) – cardboard boxes.
400 ml – glass bottles (12) – cardboard boxes.
400 ml – glass bottles (15) – cardboard boxes.
250 ml – polymer containers (1) – film bags.
500 ml – polymer containers (1) – film bags.
250 ml – polymer containers (1) – cardboard packs.
500 ml – polymer containers (1) – cardboard packs.
250 ml – polymer containers (24) – cardboard boxes.
250 ml – polymer containers (28) – cardboard boxes.
500 ml – polymer containers (12) – cardboard boxes.
500 ml – polymer containers (15) – cardboard boxes.
Solution for infusion: containers 50 ml, 100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml from 6 to 75 pcs.
Marketing Authorization Holder
Medsintez Plant, LLC (Russia)
Dosage Form
|
Ringer's solution | Solution for infusion: containers 50 ml, 100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml from 6 to 75 pcs. |
Dosage Form, Packaging, and Composition
Solution for infusion in the form of a transparent, colorless liquid.
| 1 L | |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride* | 0.25 g, |
| Ionic composition: sodium ion 147.2 mmol/L potassium ion 4 mmol/L calcium ion 2.25 mmol/L chloride ion 155.7 mmol/L Theoretical osmolarity 309 mOsm/L |
|
* (calculated as anhydrous calcium chloride)
Excipients: water for injections – up to 1 L.
50 ml – polymer containers with 2 ports (16) – bagsx (16) – cardboard boxes (for hospitals).
100 ml – polymer containers with 2 ports (50) – bagsx (50) – cardboard boxes (for hospitals).
100 ml – polymer containers with 2 ports (75) – bagsx (75) – cardboard boxes (for hospitals).
200 ml – polymer containers with 2 ports (30) – bagsx (30) – cardboard boxes (for hospitals).
250 ml – polymer containers with 2 ports (24) – bagsx (24) – cardboard boxes (for hospitals).
250 ml – polymer containers with 2 ports (36) – bagsx (36) – cardboard boxes (for hospitals).
400 ml – polymer containers with 2 ports (15) – bagsx (15) – cardboard boxes (for hospitals).
500 ml – polymer containers with 2 ports (12) – bagsx (12) – cardboard boxes (for hospitals).
500 ml – polymer containers with 2 ports (18) – bagsx (18) – cardboard boxes (for hospitals).
1000 ml – polymer containers with 2 ports (6) – bagsx (6) – cardboard boxes (for hospitals).
1000 ml – polymer containers with 2 ports (9) – bagsx (9) – cardboard boxes (for hospitals).
x made of polyethylene or polyethylene-polyamide films (double sterile vacuum packaging)
Solution for infusion: containers 250 ml 1 or 24 pcs.
Marketing Authorization Holder
Medsintez Plant, LLC (Russia)
Dosage Form
|
Ringer's solution | Solution for infusion: containers 250 ml 1 or 24 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
250 ml – polymer containers (1) – polyethylene bags.
250 ml – polymer containers (1) – polyethylene bags (24) – cardboard boxes.
Solution for infusion: containers 500 ml 1 or 12 pcs.
Marketing Authorization Holder
Medsintez Plant, LLC (Russia)
Dosage Form
|
Ringer's solution | Solution for infusion: containers 500 ml 1 or 12 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
500 ml – polymer containers (1) – polyethylene bags.
500 ml – polymer containers (1) – polyethylene bags (12) – cardboard boxes.
Solution for infusion: containers 1 L 1 or 6 pcs.
Marketing Authorization Holder
Medsintez Plant, LLC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: containers 1 L 1 or 6 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
1 L – polymer containers (1) – polyethylene bags.
1 L – polymer containers (1) – polyethylene bags (6) – cardboard boxes.
Solution for infusion: bottle 200 ml or 400 ml
Marketing Authorization Holder
Kraspharma, PJSC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: bottle 200 ml or 400 ml |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
200 ml – glass bottles with a capacity of 250 ml (1) – cardboard packs.
200 ml – glass bottles with a capacity of 250 ml (24) – cardboard boxes.
400 ml – glass bottles with a capacity of 450 ml (1) – cardboard packs.
400 ml – glass bottles with a capacity of 450 ml (12) – cardboard boxes.
Solution for infusion: bottle 200 ml or 400 ml
Marketing Authorization Holder
Mosfarm LLC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: bottle 200 ml or 400 ml |
Dosage Form, Packaging, and Composition
Solution for infusion transparent, colorless.
| 1 L | |
| Sodium chloride | 8.6 g |
| Calcium chloride | 250 mg |
| Potassium chloride | 300 mg |
Excipients : water for injections.
Theoretical osmolarity 309 mOsm/L
200 ml – glass bottles (1) – cardboard packs.
200 ml – glass bottles (15) – cardboard boxes.
200 ml – glass bottles (28) – cardboard boxes.
400 ml – glass bottles (1) – cardboard packs.
400 ml – glass bottles (15) – cardboard boxes.
Solution for infusion: vials 200 ml, 250 ml, 400 ml or 500 ml
Marketing Authorization Holder
PFC Alium, LLC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: vials 200 ml, 250 ml, 400 ml or 500 ml |
Dosage Form, Packaging, and Composition
Solution for infusion as a transparent, colorless liquid.
| 1 L | |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride (in the form of calcium chloride hexahydrate) | 0.25 g |
| Ionic composition | |
| Sodium ion | 147.2 mmol |
| Potassium ion | 4 mmol |
| Calcium ion | 2.25 mmol |
| Chloride ion | 155.7 mmol |
Theoretical osmolality 309 mOsm/L.
Excipients : water for injections – up to 1 L.
200 ml – plastic vials (1) – cardboard packs.
250 ml – plastic vials (1) – cardboard packs.
400 ml – plastic vials (1) – cardboard packs.
500 ml – plastic vials (1) – cardboard packs.
Solution for infusion: bottles 250 ml or 500 ml 16 pcs., containers 250 ml 32 pcs., containers 500 ml 16 pcs.
Marketing Authorization Holder
Sphere-Pharm, LLC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: bottles 250 ml or 500 ml 16 pcs., containers 250 ml 32 pcs., containers 500 ml 16 pcs. |
Dosage Form, Packaging, and Composition
Solution for infusion transparent, colorless.
| 1 L | |
| Sodium chloride | 8.6 g |
| Calcium chloride | 0.3 g |
| Potassium chloride (in the form of hexahydrate) | 0.25 g, |
| Ionic composition: sodium ion 147.2 mmol/L potassium ion 4 mmol/L calcium ion 2.25 mmol/L chloride ion 155.7 mmol/L Theoretical osmolarity 309 mOsm/L |
|
Excipients : water for injections – up to 1 L.
250 ml – polyethylene bottles (16) – cardboard boxes (for hospitals).
500 ml – polyethylene bottles (16) – cardboard boxes (for hospitals).
250 ml – polymer containers (32) – cardboard boxes (for hospitals).
500 ml – polymer containers (18) – cardboard boxes (for hospitals).
Solution for infusion: bottle 200 ml 1 or 28 pcs.
Marketing Authorization Holder
Mir Chemical and Pharmaceutical Concern, LLC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: bottle 200 ml 1 or 28 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate 330 mg | 330 mg |
200 ml – bottles for blood and blood substitutes (1) – cardboard packs.
200 ml – bottles for blood and blood substitutes (28) – cardboard boxes.
Solution for infusion: bottles 200 ml, 400 ml or 500 ml, vials 200 ml, 250 ml, 400 ml, 450 ml or 500 ml
Marketing Authorization Holder
Mir Chemical and Pharmaceutical Concern, LLC (Russia)
Manufactured By
NPC Eskom, PJSC (Russia)
Or
Kontsern “MIR”, LLC (Russia)
Dosage Form
|
Ringer’s solution | Solution for infusion: bottles 200 ml, 400 ml or 500 ml, vials 200 ml, 250 ml, 400 ml, 450 ml or 500 ml |
Dosage Form, Packaging, and Composition
Solution for infusion as a colorless, transparent liquid.
| 1 L | |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride hexahydrate (calculated as anhydrous) | 0.25 g |
| Ionic composition | |
| Sodium ion | 147.2 mmol |
| Potassium ion | 4 mmol |
| Calcium ion | 2.2 mmol |
| Chloride ion | 153.4 mmol |
Excipients : water for injections – up to 1 L.
Theoretical osmolarity 307 mOsm/L.
200 ml – glass bottles (1) – cardboard packs.
400 ml – glass bottles (1) – cardboard packs.
500 ml – glass bottles (1) – cardboard packs.
200 ml – polymer vials (1) – cardboard packs.
250 ml – polymer vials (1) – cardboard packs.
400 ml – polymer vials (1) – cardboard packs.
450 ml – polymer vials (1) – cardboard packs.
500 ml – polymer vials (1) – cardboard packs.
200 ml – polymer vials (1) – plastic bags.
250 ml – polymer vials (1) – plastic bags.
400 ml – polymer vials (1) – plastic bags.
450 ml – polymer vials (1) – plastic bags.
500 ml – polymer vials (1) – plastic bags.
Solution for infusion: containers 250 ml 1 or 24 pcs.
Marketing Authorization Holder
Avexima Siberia LLC (Russia)
Dosage Form
|
Ringer | Solution for infusion: containers 250 ml 1 or 24 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
250 ml – polymer containers (1) – polyethylene bags.
250 ml – polymer containers (1) – polyethylene bags (24) – cardboard boxes.
Infusion solution: container 500 ml 1 or 12 pcs.
Marketing Authorization Holder
Avexima Siberia LLC (Russia)
Dosage Form
|
Ringer | Infusion solution: container 500 ml 1 or 12 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
500 ml – polymer containers (1) – polyethylene bags.
500 ml – polymer containers (1) – polyethylene bags (12) – cardboard boxes.
Solution for infusion: bottles 500 ml 1 or 10 pcs.
Marketing Authorization Holder
Gematek, LLC (Russia)
Dosage Form
|
Ringer | Solution for infusion: bottles 500 ml 1 or 10 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride | 250 mg |
500 ml – vials (1) – cardboard packs.
500 ml – vials (10) – cardboard boxes.
Infusion solution: fl. 250 ml 1 or 15 pcs.
Marketing Authorization Holder
Gematek, LLC (Russia)
Dosage Form
|
Ringer | Infusion solution: fl. 250 ml 1 or 15 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride | 250 mg |
250 ml – vials (1) – cardboard packs.
250 ml – vials (15) – cardboard boxes.
Solution for infusion: containers 200 ml 1 or 28 pcs., 400 ml 1 or 15 pcs.
Marketing Authorization Holder
Dalkhimpharm, JSC (Russia)
Dosage Form
|
Ringer | Solution for infusion: containers 200 ml 1 or 28 pcs., 400 ml 1 or 15 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 container |
| Compound solution of sodium chloride | 100 % |
| 1 L: sodium chloride 8.6 g Potassium chloride 0.3 g Calcium chloride hexahydrate (calculated as anhydrous) 0.25 g Ionic composition (per 1 L): Sodium ion 147.2 mmol/L Potassium ion 4.02 mmol/L Calcium ion 2.25 mmol/L Chloride ion 155.7 mmol/L Theoretical osmolarity 309 mOsm/L |
200 ml – glass bottles for blood and blood substitutes.
200 ml – glass bottles for blood (28) and blood substitutes – cardboard boxes.
400 ml – glass bottles for blood and blood substitutes.
400 ml – glass bottles for blood (15) and blood substitutes – cardboard boxes.
Infusion solution: blood bottles 400 ml 1 or 15 pcs.
Marketing Authorization Holder
Promomed Rus LLC (Russia)
Dosage Form
|
Ringer | Infusion solution: blood bottles 400 ml 1 or 15 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride | 250 mg |
400 ml – bottles (1) – cardboard packs.
400 ml – bottles (15) – cardboard boxes.
Solution for infusion: blood bottles 200 ml 1 or 28 pcs.
Marketing Authorization Holder
Promomed Rus LLC (Russia)
Dosage Form
|
Ringer | Solution for infusion: blood bottles 200 ml 1 or 28 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride | 250 mg |
200 ml – bottles (1) – cardboard packs.
200 ml – bottles (28) – cardboard boxes.
Solution for infusion: containers 500 ml 1 or 20 pcs.
Marketing Authorization Holder
Rester, CJS (Russia)
Dosage Form
|
Ringer | Solution for infusion: containers 500 ml 1 or 20 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
500 ml – polymer containers (20) – cardboard boxes.
500 ml – polymer containers.
Solution for infusion: containers 250 ml 1 or 32 pcs.
Marketing Authorization Holder
Rester, CJS (Russia)
Dosage Form
|
Ringer | Solution for infusion: containers 250 ml 1 or 32 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Sodium chloride | 8.6 g |
| Potassium chloride | 300 mg |
| Calcium chloride dihydrate | 330 mg |
250 ml – polymer containers (32) – cardboard boxes.
250 ml – polymer containers.
Solution for infusion: containers 100 ml 1, 60 or 70 pcs.
Marketing Authorization Holder
Rester, CJS (Russia)
Dosage Form
|
Ringer | Solution for infusion: containers 100 ml 1, 60 or 70 pcs. |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 cont. |
| Compound solution of sodium chloride | 100 ml |
| 1 L:…sodium chloride 8.6 g Potassium chloride 300 mg Calcium chloride dihydrate 330 mg |
100 ml – polymer containers (60) – cardboard boxes.
100 ml – polymer containers (70) – cardboard boxes.
100 ml – polymer containers.
Solution for infusion: containers 50 ml, 100 ml, 150 ml, 200 ml, 250 ml, 300 ml, 350 ml, 400 ml, 450 ml, 500 ml, 750 ml, 800 ml or 1000 ml
Marketing Authorization Holder
KFK Medpolymer, LLC (Russia)
Manufactured By
Medpolymer Firm, JSC (Russia)
Dosage Form
|
Ringer | Solution for infusion: containers 50 ml, 100 ml, 150 ml, 200 ml, 250 ml, 300 ml, 350 ml, 400 ml, 450 ml, 500 ml, 750 ml, 800 ml or 1000 ml |
Dosage Form, Packaging, and Composition
Solution for infusion as a colorless, transparent liquid.
| 1 L | |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride hexahydrate (calculated as calcium chloride) | 0.25 g |
| Ionic composition | |
| Sodium ion | 147.2 mmol |
| Potassium ion | 4 mmol |
| Calcium ion | 2.25 mmol |
| Chloride ion | 155.7 mmol |
Excipients : water for injections – up to 1 L.
Theoretical osmolarity 309 mOsm/L.
50 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
100 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
150 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
200 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
250 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
300 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
350 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
400 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
450 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
500 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
750 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
800 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC (1) – secondary bags (1) – cardboard boxes.
1000 ml – self-collapsing× polymer containers with one or two separate polypropylene injection ports type SFC(1) – secondary bags (1) – cardboard boxes.
× for single-use infusion solutions.
Solution for infusion: containers 250 ml 40 pcs. or 500 ml 20 pcs.
Marketing Authorization Holder
Sakhamedprom State Unitary Enterprise (Russia)
Dosage Form
|
Ringer's solution for infusions | Solution for infusion: containers 250 ml 40 pcs. or 500 ml 20 pcs. |
Dosage Form, Packaging, and Composition
Solution for infusion transparent, colorless.
| 1 L | |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride hexahydrate | 0.25 g |
| Ionic composition (per 1 liter): Sodium ion 147.2 mmol Potassium ion 4 mmol Calcium ion 2.2 mmol Chloride ion 153.4 mmol |
Excipients : water for injections up to 1 L.
Theoretical osmolarity 307 mOsm/L
250 ml – polymer containers (40) – cardboard boxes.
500 ml – polymer containers (20) – cardboard boxes.
Solution for infusion
Marketing Authorization Holder
Obnovlenie Pfc, JSC (Russia)
Dosage Form
|
Ringer's solution Renewal | Solution for infusion |
Dosage Form, Packaging, and Composition
Solution for infusion
| 1 L | |
| Compound solution of sodium chloride | 100% |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride (calculated as anhydrous substance) | 0.25 g |
| Ionic composition | |
| Sodium ion | 147.2 mmol |
| Potassium ion | 4 mmol |
| Calcium ion | 2.25 mmol |
| Chloride ion | 155.7 mmol |
Theoretical osmolarity 309 mOsm/L.
150 ml – vials – cardboard packs – By prescription
150 ml – vials (15 pcs.) – cardboard boxes – for hospitals
150 ml – vials (20 pcs.) – cardboard boxes – for hospitals
150 ml – vials (24 pcs.) – cardboard boxes – for hospitals
150 ml – vials (28 pcs.) – cardboard boxes – for hospitals
150 ml – vials (36 pcs.) – cardboard boxes – for hospitals
150 ml – vials (42 pcs.) – cardboard boxes – for hospitals
200 ml – vials – cardboard packs – By prescription
200 ml – vials (15 pcs.) – cardboard boxes – for hospitals
200 ml – vials (20 pcs.) – cardboard boxes – for hospitals
200 ml – vials (24 pcs.) – cardboard boxes – for hospitals
200 ml – vials (28 pcs.) – cardboard boxes – for hospitals
200 ml – vials (36 pcs.) – cardboard boxes – for hospitals
200 ml – vials (42 pcs.) – cardboard boxes – for hospitals
250 ml – vials – cardboard packs – By prescription
250 ml – vials (15 pcs.) – cardboard boxes – for hospitals
250 ml – vials (20 pcs.) – cardboard boxes – for hospitals
250 ml – vials (24 pcs.) – cardboard boxes – for hospitals
250 ml – vials (28 pcs.) – cardboard boxes – for hospitals
250 ml – vials (36 pcs.) – cardboard boxes – for hospitals
250 ml – vials (42 pcs.) – cardboard boxes – for hospitals
300 ml – vials – cardboard packs – By prescription
300 ml – vials (10 pcs.) – cardboard boxes – for hospitals
300 ml – vials (12 pcs.) – cardboard boxes – for hospitals
300 ml – vials (15 pcs.) – cardboard boxes – for hospitals
300 ml – vials (20 pcs.) – cardboard boxes – for hospitals
300 ml – vials (24 pcs.) – cardboard boxes – for hospitals
300 ml – vials (28 pcs.) – cardboard boxes – for hospitals
350 ml – vials – cardboard packs – By prescription
350 ml – vials (10 pcs.) – cardboard boxes – for hospitals
350 ml – vials (12 pcs.) – cardboard boxes – for hospitals
350 ml – vials (15 pcs.) – cardboard boxes – for hospitals
350 ml – vials (20 pcs.) – cardboard boxes – for hospitals
350 ml – vials (24 pcs.) – cardboard boxes – for hospitals
350 ml – vials (28 pcs.) – cardboard boxes – for hospitals
400 ml – vials – cardboard packs – By prescription
400 ml – vials (10 pcs.) – cardboard boxes – for hospitals
400 ml – vials (12 pcs.) – cardboard boxes – for hospitals
400 ml – vials (15 pcs.) – cardboard boxes – for hospitals
400 ml – vials (20 pcs.) – cardboard boxes – for hospitals
400 ml – vials (24 pcs.) – cardboard boxes – for hospitals
400 ml – vials (28 pcs.) – cardboard boxes – for hospitals
500 ml – vials – cardboard packs – By prescription
500 ml – vials (10 pcs.) – cardboard boxes – for hospitals
500 ml – vials (12 pcs.) – cardboard boxes – for hospitals
500 ml – vials (15 pcs.) – cardboard boxes – for hospitals
500 ml – vials (20 pcs.) – cardboard boxes – for hospitals
500 ml – vials (24 pcs.) – cardboard boxes – for hospitals
500 ml – vials (28 pcs.) – cardboard boxes – for hospitals
Solution for infusion: 100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml vials
Marketing Authorization Holder
Grotex, LLC (Russia)
Dosage Form
|
Ringer-SOLOpharm | Solution for infusion: 100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml vials |
Dosage Form, Packaging, and Composition
| Solution for infusion | 1 L |
| Compound solution of sodium chloride | 100% |
| Sodium chloride | 8.6 g |
| Potassium chloride | 0.3 g |
| Calcium chloride hexahydrate (calculated as anhydrous) | 0.25 g |
| Ionic composition Sodium ion |
147.2 mmol |
| Potassium ion | 4 mmol |
| Calcium ion | 2.25 mmol |
| Chloride ion | 155.7 mmol |
Excipients : water for injections up to 1 L.
Theoretical osmolality 309 mOsm/L.
100 ml – polypropylene vials (1) – cardboard packs.
200 ml – polypropylene vials (1) – cardboard packs.
250 ml – polypropylene vials (1) – cardboard packs.
400 ml – polypropylene vials (1) – cardboard packs.
500 ml – polypropylene vials (1) – cardboard packs.
1000 ml – polypropylene vials (1) – cardboard packs.
100 ml – polypropylene vials (30) – cardboard boxes (for hospitals).
200 ml – polypropylene vials (20) – cardboard boxes (for hospitals).
250 ml – polypropylene vials (20) – cardboard boxes (for hospitals).
400 ml – polypropylene vials (20) – cardboard boxes (for hospitals).
500 ml – polypropylene vials (20) – cardboard boxes (for hospitals).
1000 ml – polypropylene vials (10) – cardboard boxes (for hospitals).
![Ringer [Solution] 1](https://www.medixlife.com/wp-content/uploads/Medixlife_favi_512.png "Ringer [Solution] 2")