Sanguilar (Solution) Instructions for Use

Marketing Authorization Holder

PharmVILAR NPO, LLC (Russia)

ATC Code

D08AX (Other antiseptics and disinfectants)

Dosage Form

Sanguilar

Solution for external and topical use (alcoholic) 0.2%: 10 ml, 25 ml, 50 ml or 100 ml fl.

Dosage Form, Packaging, and Composition

Solution for external and topical use transparent, orange in color, with an alcohol odor.

Excipients: ethyl alcohol 95% – 315 ml, purified water – up to 1000 ml.

10 ml – bottles (1) – cardboard packs.
25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.

Clinical-Pharmacological Group

Antiseptic for external and topical use

Pharmacotherapeutic Group

Antibiotics and antimicrobial agents used in dermatology; antimicrobial agents for topical use; other antimicrobial agents

Pharmacological Action

It has a broad spectrum of antimicrobial action.

Active against gram-positive and gram-negative bacteria (Staphylococcus spp., Streptococcus spp., Enterococcus spp., Shigella spp., Escherichia spp., Salmonella spp., Proteus spp., Acinetobacter spp., Citrobacter spp., Pseudomonas spp., Serratia spp., Klebsiella spp., Antracoides spp., Cryptococcus spp.), pathogenic fungi of the genus Microsporum, Trichophyton, Nocardia, Aspergillus, yeast-like fungi of the genus Candida (including polyresistant strains of microorganisms), as well as Actinomyces and some pathogenic protozoa (Entamoeba histolytica, Trichomonas vaginalis).

The mechanism of the antimicrobial action of sanguirithrin is based on the suppression of bacterial nuclease, disruption of the permeability processes of cell walls, division septa, and nucleoid structure.

Active against many polyresistant strains of microorganisms.

It has anticholinesterase activity.

Indications

For oral administration

As part of complex therapy for acute and chronic purulent-inflammatory diseases: acute intestinal infections (dysentery, salmonellosis, food toxicoinfections); wound infections and various infectious complications caused by pathogenic microflora (convalescent bacterial carriage); diseases associated with impaired normal microflora (dysbacteriosis), as well as diseases caused by pathogenic fungi (pharyngomycosis, candidiasis, microsporia).

For external and topical use

For the treatment of: infectious-inflammatory diseases of the skin and mucous membranes of bacterial and fungal etiology, including Candida albicans; in dentistry for aphthous stomatitis, ulcerative-necrotic gingivostomatitis; in surgery – for infected burns, long-term non-healing wounds and ulcers; in gynecology – endocervicitis, colpitis, vaginitis, cervical erosion; in dermatology – pyoderma, superficial blastomycosis, dermatomycosis, uncomplicated forms of fungal infections of smooth skin without signs of eczematization; in ENT practice – tonsillitis, external otitis, chronic purulent otitis media.

For the prevention of purulent-inflammatory skin diseases in newborns; wound infections in surgery.

ICD codes

Dosage Regimen

When taken orally, the dose is set individually, depending on age. A single dose is 5-10 mg, the frequency of administration is 2-4 times/day. The duration of the treatment course depends on the nosological form and severity of the disease.

For external and topical use, the regimen depends on the dosage form used, indications, and patient age.

In newborns and young children, it is used in the appropriate dosage form.

Adverse Reactions

From the digestive system when taken orally, nausea, vomiting, diarrhea, abdominal pain are possible.

For external and topical use: allergic reactions and burning at the application site, a sensation of bitterness when treating the oral cavity are possible.

Contraindications

Epilepsy; hyperkinesis; bronchial asthma; coronary artery disease; severe liver and/or kidney diseases with impaired function; fungal skin lesions with signs of eczematization; children under 3 years of age (for oral administration); hypersensitivity to the active substance.

Use in Pregnancy and Lactation

Use during pregnancy and breastfeeding is possible if the expected benefit of therapy for the mother outweighs the potential risk to the fetus or breastfed infant.

Use in Hepatic Impairment

Contraindicated in hepatic insufficiency.

Use in Renal Impairment

Contraindicated in renal insufficiency.

Pediatric Use

Oral administration is contraindicated in children under 3 years of age.

Geriatric Use

Use with caution in elderly patients to avoid exacerbation of chronic diseases.

Special Precautions

Do not allow the medication to get into the eyes. If this product gets into the eyes, rinse them with plenty of water.

Drug Interactions

External and topical use in combination with local anesthetics (including procaine, trimecaine) is possible.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.