Tactivin (Solution) Instructions for Use

Marketing Authorization Holder

Biomed named after I.I.Mechnikov, PJSC (Russia)

ATC Code

L03AX (Other immunostimulants)

Active Substance

Thymus extract (Grouping name)

Dosage Form

Tactivin

Solution for subcutaneous injection 100 mcg/1 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

1 ml – ampoules (10) – carton packs.

Clinical-Pharmacological Group

Immunostimulating drug

Pharmacotherapeutic Group

Immunostimulating agent

Pharmacological Action

Immunostimulating agent.

It restores impaired immunological reactivity (regulates the number and ratio of T- and B-lymphocytes and their subpopulations, stimulates cellular immune responses, enhances phagocytosis), stimulates regeneration and hematopoiesis processes when they are suppressed, and also improves the course of cellular metabolism processes.

Indications

Immunodeficiency states in adults and children (from 6 months to 14 years) in: infectious purulent and septic processes; persistent disorders of thymus function (radiation sickness, thymus tumors, surgical removal of the thymus); acute and chronic viral and bacterial infections; impaired regenerative processes; suppression of immunity and hematopoiesis after chemotherapy or radiation therapy in cancer patients.

ICD codes

Dosage Regimen

Administer Tactivin by subcutaneous injection.

The standard treatment course is 3 to 10 days, with duration determined by the severity of the immune disorder.

For adults, the daily dose is 5 to 20 mcg, resulting in a total course dose of 30 to 100 mcg.

For pediatric patients, calculate the daily dose based on age: administer 1 mcg for children under 1 year; 1.5 to 2 mcg for children aged 1 to 3 years; 2 to 3 mcg for children aged 4 to 6 years; and 3 to 5 mcg for children aged 7 to 14 years.

If required, a repeat course of therapy may be conducted after an interval of 1 to 6 months.

Adverse Reactions

Systemic reactions allergic reactions (itching, edema, urticaria, skin rash, anaphylactic, anaphylactoid reactions).

Contraindications

Pregnancy and the period of breastfeeding.

Use in Pregnancy and Lactation

Use is contraindicated during pregnancy and breastfeeding.

Pediatric Use

Approved for use in children and adolescents under 18 years of age.

Geriatric Use

There are no specific restrictions for use.

Special Precautions

It is not recommended to consume alcoholic beverages during therapy with thymus extract.

Drug Interactions

Thymus extract is compatible with isoniazid, immunostimulating drugs, corticosteroids, rifampicin, analgesics.

Storage Conditions

Store at 2°C (36°F) to 8°C (46°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.