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Terebinthin ointment (Ointment) Instructions for Use

ATC Code

N02 (Analgesics)

Active Substance

Turpentine oil (BP British Pharmacopoeia)

Clinical-Pharmacological Group

Drug with local irritant and analgesic action

Pharmacotherapeutic Group

Drugs for external use for muscle and joint pain; other drugs for external use for muscle and joint pain

Pharmacological Action

A herbal remedy. It has a local irritant, distracting, and antiseptic effect. The main active substance of turpentine oil (purified turpentine), the terpene alpha-pinene, is lipophilic, easily penetrates the epidermis, and irritates the endings of sensory nerves.

A certain contribution is also apparently made by endogenous biologically active substances released under the influence of the oil. Histamine and other inflammatory mediators cause vasodilation, slight tissue swelling, and hyperemia. Enkephalins and endorphins contribute to pain relief.

The mechanism of the distracting action is explained by the fact that two streams of excitation enter the central nervous system – from pathologically altered internal organs and from the skin surface, with the latter dominating. The perception of afferent impulsation is weakened.

Furthermore, a trophic influence is carried out through the cutaneous-visceral reflex (when irritating the Zakharyin-Ged sensitive zones) and by the type of axon-reflex (antidromically via postganglionic sympathetic fibers). When administered by inhalation, alpha-pinene reflexively stimulates coughing and has expectorant and mucolytic effects.

Indications

As an auxiliary remedy for rheumatic pains, arthralgia, neuralgia, myalgia, lumbosciatica.

ICD codes

ICD-10 code Indication
M05 Seropositive rheumatoid arthritis
M25.5 Pain in joint
M42 Spinal osteochondrosis
M54.1 Radiculopathy
M54.3 Sciatica
M54.4 Lumbago with sciatica
M79.0 Unspecified rheumatism
M79.1 Myalgia
M79.2 Neuralgia and neuritis, unspecified
ICD-11 code Indication
8B93.Z Radiculopathy, unspecified
8E4A.1 Paraneoplastic or autoimmune diseases of the peripheral or autonomic nervous system
FA20.0 Seropositive rheumatoid arthritis
FA27.2 Palindromic rheumatism
FA85.Z Defects of vertebral end-plates, unspecified
FB51.3 Fibroblastic rheumatism
FB56 Specified soft tissue diseases, not elsewhere classified
FB56.2 Myalgia
ME82 Pain in joint
ME84.20 Lumbago with sciatica
ME84.3 Sciatica

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Apply the ointment externally in a thin layer to intact skin over the affected area.

Use two to three times daily; the frequency may be adjusted based on symptom severity and individual response.

Rub the ointment in gently until fully absorbed. Avoid application to damaged skin, mucous membranes, or eyes.

Limit the area of application to minimize systemic absorption and potential for adverse effects.

Wash hands thoroughly with soap and water after each use to prevent accidental contact with sensitive areas.

The typical treatment duration is for short-term use; do not exceed 7 to 10 days of continuous application without medical consultation.

Discontinue use and seek medical advice if symptoms persist, worsen, or if severe skin irritation, redness, or burning occurs.

Do not apply under occlusive dressings or bandages, as this increases systemic absorption and the risk of local skin reactions.

For musculoskeletal pain such as myalgia, arthralgia, or lumbosciatica, apply directly to the painful area.

Do not use on large areas of the body simultaneously. Use the minimum effective amount necessary for symptomatic relief.

Adverse Reactions

Possible allergic reactions, skin hyperemia and itching.

Contraindications

Hypersensitivity to turpentine oil; impaired skin integrity, inflammatory skin diseases at the site of intended application; pregnancy, breastfeeding period; children and adolescents under 18 years of age.

With caution: hepatic and/or renal failure.

Use in Pregnancy and Lactation

Contraindicated for use during pregnancy and lactation (breastfeeding).

Use in Hepatic Impairment

Should be used with caution in hepatic insufficiency.

Use in Renal Impairment

Should be used with caution in renal insufficiency.

Pediatric Use

Contraindicated for use in children and adolescents under 18 years of age.

Special Precautions

Should not be used at elevated body temperature.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Marketing Authorization Holder

Genel RD, LLC (Russia)

Dosage Form

Bottle OTC Icon Terebinthin ointment Ointment for external use 20%: 25 g jars, tubes, or fl.

Dosage Form, Packaging, and Composition

Ointment for external use 100 g
Turpentine oil 20 g

25 g – tubes (1) – cardboard packs.
25 g – jars (1) – cardboard packs.
25 g – bottles (1) – cardboard packs.

Marketing Authorization Holder

Moscow Pharmaceutical Factory CJS (Russia)

Dosage Form

Bottle OTC Icon Terebinthin ointment Ointment for external use 20%: 25 g jar, 25 or 50 g tubes.

Dosage Form, Packaging, and Composition

Ointment for external use 20% 100 g
Turpentine oil 20 g

25 g – dark glass jars (1) – cardboard packs.
25 g – aluminum tubes (1) – cardboard packs.
50 g – aluminum tubes (1) – cardboard packs.

Marketing Authorization Holder

Tula Pharmaceutical Factory, LLC (Russia)

Dosage Form

Bottle OTC Icon Terebinthin ointment Ointment for external use 20%: 25 g jars, 25 or 50 g tubes

Dosage Form, Packaging, and Composition

Ointment for external use 20% 100 g
Turpentine oil 20 g

25 g – jars (1) – cardboard packs.
25 g – aluminum tubes (1) – cardboard packs.
50 g – aluminum tubes (1) – cardboard packs.

Marketing Authorization Holder

Tula Pharmaceutical Factory, LLC (Russia)

Dosage Form

Bottle OTC Icon Terebinthin ointment Ointment for external use 20%: jars or tubes

Dosage Form, Packaging, and Composition

Ointment for external use 100 g
Turpentine oil 20 g

Tubes (1) – cardboard packs.
Jars (1) – cardboard packs.
Tubes – group packaging.
Jars – group packaging.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle OTC Icon Terebinthin ointment Ointment for external use 20%: 15, 20, 25, or 30 g jars, 25 or 30 g tubes

Dosage Form, Packaging, and Composition

Ointment for external use white with a yellowish tint, homogeneous, with the smell of turpentine.

100 g
Turpentine oil purified essential (oleum terebinthinae) 20 g

Excipients: petrolatum – 48 g, emulsifier T2 (grade A) – 8 g, purified water – 24 g.

15 g – dark glass jars (1) – cardboard packs.
20 g – dark glass jars (1) – cardboard packs.
25 g – dark glass jars (1) – cardboard packs.
30 g – dark glass jars (1) – cardboard packs.
25 g – aluminum tubes (1) – cardboard packs.
30 g – aluminum tubes (1) – cardboard packs.

Marketing Authorization Holder

Yaroslavl Pharmaceutical Factory, CJSC (Russia)

Dosage Form

Bottle OTC Icon Terebinthin ointment Ointment for external use 20%: jar 25 g

Dosage Form, Packaging, and Composition

Ointment for external use 20% 100 g
Turpentine oil 20 g

25 g – dark glass jars (1) – cardboard packs.

Marketing Authorization Holder

Aromasintez, LLC (Russia)

Dosage Form

Bottle OTC Icon Turpentine oil Ointment for external use: 25 ml, 30 ml, 40 ml, 50 ml, or 100 ml fl.

Dosage Form, Packaging, and Composition

Ointment for external use in the form of a transparent, colorless or slightly yellowish liquid with a characteristic odor.

100 ml
Turpentine oil 100 ml

25 ml – bottles – cardboard packs.
25 ml – bottles (50) – cardboard boxes (for hospitals).
25 ml – bottles (100) – cardboard boxes (for hospitals).
25 ml – bottles (150) – cardboard boxes (for hospitals).
25 ml – bottles (200) – cardboard boxes (for hospitals).
30 ml – bottles – cardboard packs.
30 ml – bottles (50) – cardboard boxes (for hospitals).
30 ml – bottles (100) – cardboard boxes (for hospitals).
30 ml – bottles (150) – cardboard boxes (for hospitals).
30 ml – bottles (200) – cardboard boxes (for hospitals).
40 ml – bottles – cardboard packs.
40 ml – bottles (30) – cardboard boxes (for hospitals).
40 ml – bottles (50) – cardboard boxes (for hospitals).
40 ml – bottles (80) – cardboard boxes (for hospitals).
40 ml – bottles (100) – cardboard boxes (for hospitals).
40 ml – bottles (120) – cardboard boxes (for hospitals).
40 ml – bottles (150) – cardboard boxes (for hospitals).
50 ml – bottles – cardboard packs.
50 ml – bottles (30) – cardboard boxes (for hospitals).
50 ml – bottles (50) – cardboard boxes (for hospitals).
50 ml – bottles (80) – cardboard boxes (for hospitals).
50 ml – bottles (100) – cardboard boxes (for hospitals).
50 ml – bottles (120) – cardboard boxes (for hospitals).
50 ml – bottles (150) – cardboard boxes (for hospitals).
100 ml – bottles – cardboard packs.
100 ml – bottles (30) – cardboard boxes (for hospitals).
100 ml – bottles (50) – cardboard boxes (for hospitals).
100 ml – bottles (80) – cardboard boxes (for hospitals).
100 ml – bottles (100) – cardboard boxes (for hospitals).

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