Artracam^® (Powder) Instructions for Use

Marketing Authorization Holder

Incampharm, LLC (Russia)

Manufactured By

PharmVILAR NPO, LLC (Russia)

Contact Information

Incampharm LLC (Russia)

ATC Code

M01AX05 (Glucosamine)

Active Substance

Glucosamine (Rec.INN registered by WHO)

Dosage Form

Artracam®

Powder for oral solution 1.5 g: sachet 2.2 g 20 pcs.

Dosage Form, Packaging, and Composition

Powder for preparation of oral solution white or white with a slightly yellowish tint.

Excipients: sorbitol – 0.296 g, citric acid – 0.02 g.

2.2 g – heat-sealed sachets (20) – cardboard packs.

Clinical-Pharmacological Group

Drug affecting metabolism in cartilage tissue. Proteoglycan biosynthesis stimulator

Pharmacotherapeutic Group

Tissue repair stimulant

Pharmacological Action

Glucosamine sulfate has anti-inflammatory and analgesic effects, replenishes endogenous glucosamine deficiency, stimulates the synthesis of proteoglycans and hyaluronic acid in the synovial fluid.

It increases the permeability of the joint capsule, restores enzymatic processes in the cells of the synovial membrane and articular cartilage.

It promotes sulfur fixation in the process of chondroitin sulfuric acid synthesis, inhibits the development of degenerative processes in the joints, restores their function, and reduces joint pain.

Pharmacokinetics

Absorption from the gastrointestinal tract – 90%, bioavailability – 26%, T_1/2– 70 h.

Indications

• Osteoarthritis of peripheral joints;
• Osteoarthritis of spinal joints;
• Osteochondrosis.

ICD codes

Dosage Regimen

Administer the drug orally.

Dissolve the contents of one sachet in a full glass (200 ml) of water immediately before use.

Take the prepared solution once per day, preferably with a meal.

The standard course of treatment is 6 weeks.

On a physician’s recommendation, the treatment course may be repeated.

Maintain an interval of 2 months between consecutive treatment courses.

Do not exceed the recommended duration of use without medical supervision.

Adverse Reactions

The drug is well tolerated; in some cases, the following are possible: gastralgia, flatulence, diarrhea, constipation, allergic reactions – urticaria, itching.

Contraindications

• Individual hypersensitivity to glucosamine sulfate and other components of the drug;
• Severe chronic renal failure;
• Pregnancy;
• Lactation period;
• It is not recommended to prescribe the drug in childhood (under 12 years) due to the lack of clinical data in this category of patients.

The drug should be prescribed with caution in case of intolerance to seafood (shrimp, shellfish), due to an increased likelihood of developing allergic reactions, as well as to patients with bronchial asthma, diabetes mellitus.

Use in Pregnancy and Lactation

The use of the drug is contraindicated during pregnancy and lactation.

Use in Renal Impairment

Contraindication: severe chronic renal failure.

Pediatric Use

Contraindicated: children under 12 years of age.

Special Precautions

Effect on the ability to drive vehicles and mechanisms

There are no data on the effect on the ability to drive vehicles and operate machinery.

Overdose

Cases of overdose are unknown.

Treatment: gastric lavage, symptomatic therapy.

Drug Interactions

It is compatible with NSAIDs, paracetamol, and corticosteroids.

It increases the absorption of tetracyclines and decreases the absorption of semi-synthetic penicillins, chloramphenicol.

Storage Conditions

The drug should be stored in a place protected from light, out of the reach of children, at a temperature not exceeding 25°C (77°F).

Shelf Life

Shelf life – 3 years. Do not use after the expiration date.

Dispensing Status

The drug is dispensed without a prescription.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.