Combutec-2 (Sponge) Instructions for Use

Instructions
Dosage forms

ATC Code

D08AF (Nitrofuran derivatives)

Clinical-Pharmacological Group

A drug improving trophism and tissue regeneration, with antimicrobial activity for external use

Pharmacotherapeutic Group

Dermatoprotective agent

Pharmacological Action

Dermatoprotective agent. It is used to protect wound and burn surfaces, exerts an antiseptic effect, and promotes the development of granulations.

Indications

Second and third-degree A burns (covering surfaces cleansed of necrotic tissues); third-degree B burns (after eschar removal); flat granulating post-traumatic wounds; trophic ulcers; bedsores; autodermoplasty (wound preparation); covering donor sites after autodermoplasty.

ICD codes

Open the list of ICD codes

ICD-10 code	Indication
L89	Decubitus ulcer and pressure area
L98.4	Chronic skin ulcer, not elsewhere classified
T14.1	Open wound of unspecified body region
T30	Burns and corrosions of unspecified body region
Z51.4	Preparatory procedures for subsequent treatment or examination, not elsewhere classified

ICD-11 code	Indication
EA40	Tropical phagedenic ulcer
EF60	Ischemic ulceration of the skin
EH90.Z	Pressure ulcer of unspecified degree
EM0Z	Unspecified skin disorder
ME60.2	Ulcerative skin lesion of unspecified nature
ND56.1	Open wound of unspecified body region
NE11	Burn of unspecified body region
QB9A	Preparatory procedures for subsequent treatment

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Sponge

The plate is applied to the wound (including after harvesting a skin graft) with the porous surface, and its edges should overlap the wound edges by 0.5-1 cm.

The plate is fixed with 1-2 layers of gauze (without cotton wool).

The condition of the wound surface is monitored daily, once a day with scant exudate, twice a day with copious exudate.

Autodermoplasty is performed on areas where succulent pink granulations form under the plate.

Leave on the donor site until self-detachment upon complete epithelialization of the wound.

For post-traumatic wounds, it is recommended to use after cleansing the wound of necrotic tissues, with the beginning growth of healthy granulations, and during the epithelialization of small wounds.

For trophic ulcers and bedsores, it is recommended to use after cleansing the wound surface of necrotic tissues and achieving low bacterial contamination.

Adverse Reactions

Secondary infection; allergic reactions.

Contraindications

Hypersensitivity; copious wound exudation; skin necrosis; infected wounds (more than 100 thousand microbial bodies per 1 g of tissue).

Storage Conditions

Store at 15°C (59°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer