Dexpanthenol (Ointment, Foam) Instructions for Use
ATC Code
D03AX03 (Dexpanthenol)
Active Substance
Dexpanthenol (Rec.INN registered by WHO)
Clinical-Pharmacological Group
A drug improving trophism and tissue regeneration, for external use
Pharmacotherapeutic Group
Tissue repair stimulant
Pharmacological Action
Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid is a water-soluble B-group vitamin and is a component of coenzyme A.
It stimulates skin regeneration, normalizes cell metabolism, and increases the strength of collagen fibers.
An increased need for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated for by the topical application of dexpanthenol.
Its optimal molecular weight, hydrophilicity, and low polarity enable it to penetrate all layers of the skin.
It has a regenerating and weak anti-inflammatory effect.
Pharmacokinetics
When applied topically, it is rapidly absorbed and converted into pantothenic acid, binding to plasma proteins (mainly beta-globulin and albumin).
Indications
- Violations of skin integrity caused by mechanical, chemical, temperature factors, or after surgical interventions (burns of various origins (including sunburns); scratches, abrasions, wounds; bedsores; poorly healing skin grafts; aseptic postoperative wounds);
- Inflammatory processes on the skin; dermatitis; boils; trophic ulcers of the lower extremities; care for the skin around tracheostomies, gastrostomies, and colostomies;
- Treatment and prevention of the consequences of adverse environmental effects on the skin (cold, wind, dampness);
- In children – diaper dermatitis, scratches and minor irritation after exposure to the sun, ultraviolet and X-ray radiation; treatment and prevention of diaper rash;
- Cracks and inflammation of the nipples of the mammary glands in nursing mothers;
- For the treatment and protection of dry skin as a source of neutral fats and dexpanthenol.
ICD codes
| ICD-10 code | Indication |
| L02 | Cutaneous abscess, furuncle and carbuncle |
| L20.8 | Other atopic dermatitis (neurodermatitis, eczema) |
| L22 | Diaper dermatitis |
| L30.4 | Erythematous intertrigo |
| L30.9 | Dermatitis, unspecified |
| L55 | Sunburn |
| L56.2 | Photocontact dermatitis [berloque dermatitis] |
| L89 | Decubitus ulcer and pressure area |
| L98.4 | Chronic skin ulcer, not elsewhere classified |
| N64.0 | Fissure and fistula of nipple |
| T14.0 | Superficial injury of unspecified body region (including abrasion, bruise, contusion, hematoma, bite of nonvenomous insect) |
| T14.1 | Open wound of unspecified body region |
| T30 | Burns and corrosions of unspecified body region |
| Z58.8 | Other problems related to physical environmental factors |
| Z93.0 | Tracheostomy status |
| Z93.1 | Gastrostomy status |
| Z93.3 | Colostomy status |
| Z94.6 | Presence of transplanted bone |
| ICD-11 code | Indication |
| 1B75.0 | Furuncle |
| 1B75.1 | Carbuncle |
| 1B75.2 | Furunculosis |
| 1B75.3 | Pyogenic skin abscess |
| 9A06.70 | Atopic eczema of the eyelids |
| EA40 | Tropical phagedenic ulcer |
| EA80.0 | Infantile atopic eczema |
| EA80.1 | Childhood atopic eczema |
| EA80.2 | Adult atopic eczema |
| EA80.Z | Atopic eczema, unspecified |
| EA85.20 | Atopic hand eczema |
| EA85.2Z | Hand dermatitis, unspecified |
| EA85.3 | Foot dermatitis |
| EA89 | Generalized eczematous dermatitis of unspecified type |
| EA8Z | Dermatitis or eczema, unspecified |
| EF60 | Ischemic ulceration of the skin |
| EH40.10 | Diaper dermatitis |
| EH90.Z | Pressure ulcer of unspecified degree |
| EH92 | Dermatoses provoked by friction or mechanical impact |
| EH92.1 | Blister due to friction |
| EK02.20 | Intertriginous dermatitis due to friction, sweating or contact with body fluids |
| EK20 | Photoallergic reaction to fragrances or cosmetic products |
| EM0Z | Unspecified skin disorder |
| GB23.1 | Fissure or fistula of nipple |
| ME60.2 | Ulcerative skin lesion of unspecified nature |
| ND56.0 | Superficial injury of unspecified body region |
| ND56.1 | Open wound of unspecified body region |
| NE11 | Burn of unspecified body region |
| QB61.0 | Tracheostomy status |
| QB61.2 | Gastrostomy status |
| QB61.4 | Colostomy status |
| QB63.5 | Presence of transplanted bone |
| QD70.Z | Problems related to the natural environment or anthropogenic changes in the environment, unspecified |
| QD7Z | Problems related to the environment, unspecified |
Dosage Regimen
| The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen. |
Ointment
The ointment is applied 2-4 times a day (more often if necessary) in a thin layer to the affected area of the skin, rubbing in gently.
If applied to an infected skin surface, it should first be treated with any antiseptic.
Nursing mothers should apply the ointment to the nipple surface after each breastfeeding.
For infants, the ointment is applied after each diaper change or water procedure.
Foam
Apply externally to the affected skin surface or for care and rub in gently. The frequency of application depends on the indications.
Adverse Reactions
Adverse effects develop extremely rarely. Mild allergic reactions are possible.
Contraindications
- Hypersensitivity to any of the components of the drug.
Use in Pregnancy and Lactation
According to indications: cracks and inflammation of the nipples of the mammary glands in nursing mothers.
Pediatric Use
Used according to indications.
Special Precautions
Treatment of trophic ulcers and poorly healing skin grafts should be carried out under the supervision of the attending physician.
Do not apply to weeping wounds.
Storage Conditions
Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.
Dispensing Status
Over-the-Counter
Important Safety Information
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.
Medical DisclaimerBrand (or Active Substance), Marketing Authorisation Holder, Dosage Form
Ointment for external use 5%: tube 30 g
Marketing Authorization Holder
Vertex, JSC (Russia)
Dosage Form
 |
Dexpanthenol | Ointment for external use 5%: tube 30 g |
Dosage Form, Packaging, and Composition
Ointment for external use 5% light yellow in color, homogeneous, with a characteristic smell of lanolin.
| 1 g | |
| Dexpanthenol | 50 mg |
Excipients: petrolatum, white petrolatum, liquid paraffin, isopropyl myristate, methylparahydroxybenzoate (nipagin), propylparahydroxybenzoate (nipazol), purified water.
30 g – aluminum tubes (1) – cardboard packs.
Ointment for external use 5%: jars or tubes 25 g, 30 g, 40 g, 50 g, or 100 g
Marketing Authorization Holder
West, LLC (Russia)
Manufactured By
Samaramedprom, OJSC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: jars or tubes 25 g, 30 g, 40 g, 50 g, or 100 g |
Dosage Form, Packaging, and Composition
Ointment for external use from white with a yellowish tint to light yellow, homogeneous, with a characteristic smell.
| 100 g | |
| Dexpanthenol | 5 g |
Excipients: petrolatum – 13 g, liquid paraffin – 20 g, lanolin – 25 g, cetearyl alcohol [cetyl alcohol 60%, stearyl alcohol 40%] – 3 g, white beeswax – 3 g, methylparahydroxybenzoate – 0.07 g, propylparahydroxybenzoate – 0.03 g, purified water – 30.9 g.
25 g – jars (1) – cardboard packs.
30 g – jars (1) – cardboard packs.
40 g – jars (1) – cardboard packs.
50 g – jars (1) – cardboard packs.
100 g – jars (1) – cardboard packs.
25 g – tubes (1) – cardboard packs.
30 g – tubes (1) – cardboard packs.
40 g – tubes (1) – cardboard packs.
50 g – tubes (1) – cardboard packs.
100 g – tubes (1) – cardboard packs.
Foam for external use 5%: canister 58 g
Marketing Authorization Holder
West, LLC (Russia)
Manufactured By
Samaramedprom, OJSC (Russia)
Dosage Form
|
Dexpanthenol | Foam for external use 5%: canister 58 g |
Dosage Form, Packaging, and Composition
Foam for external use white in color (formed upon release from the canister), with a faint characteristic odor.
| 1 canister | |
| Dexpanthenol | 2.5 g |
Excipients: cetostearyl alcohol emulsifying type A [cetostearyl alcohol 80%, sodium cetostearyl sulfate 7%], macrogol glyceryl cocoate, propylene glycol, methylparahydroxybenzoate, potassium dihydrogen phosphate, sodium phosphate dodecahydrate, purified water, tetrafluoroethane (propellant 134a).
58 g – aluminum aerosol canisters (1) with a continuous action valve and sprayer – cardboard packs.
Ointment for external use 5%: tubes 15 g, 20 g, 25 g, 30 g, 35 g, 40 g, 50 g, 60 g, 70 g, 80 g, or 100 g
Marketing Authorization Holder
Vita Line, LLC (Russia)
Manufactured By
Tula Pharmaceutical Factory, LLC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: tubes 15 g, 20 g, 25 g, 30 g, 35 g, 40 g, 50 g, 60 g, 70 g, 80 g, or 100 g |
Dosage Form, Packaging, and Composition
Ointment for external use homogeneous, from white with a yellowish tint to light yellow, with a specific odor.
| 100 g | |
| Dexpanthenol | 5 g |
Excipients: petrolatum – 27 g, liquid paraffin – 10 g, lanolin – 17 g, cholesterol – 0.5 g, isopropyl myristate – 3 g, methylparahydroxybenzoate – 0.07 g, propylparahydroxybenzoate – 0.03 g, purified water – 37.4 g.
15 g – tubes (1) – cardboard packs (1).
20 g – tubes (1) – cardboard packs (1).
25 g – tubes (1) – cardboard packs (1).
30 g – tubes (1) – cardboard packs (1).
35 g – tubes (1) – cardboard packs (1).
40 g – tubes (1) – cardboard packs (1).
50 g – tubes (1) – cardboard packs (1).
60 g – tubes (1) – cardboard packs (1).
70 g – tubes (1) – cardboard packs (1).
80 g – tubes (1) – cardboard packs (1).
100 g – tubes (1) – cardboard packs (1).
Ointment for external use 5%: jars 25 g, 30 g, 40 g, 50 g, or 100 g; tubes 25 g, 30 g, 40 g, 50 g, or 100 g
Marketing Authorization Holder
Ivanovo Pharmaceutical Factory PJSC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: jars 25 g, 30 g, 40 g, 50 g, or 100 g; tubes 25 g, 30 g, 40 g, 50 g, or 100 g |
Dosage Form, Packaging, and Composition
Ointment for external use homogeneous from white with a yellowish tint to light yellow with a characteristic odor.
| 100 g | |
| Dexpanthenol | 5 g |
Excipients: petrolatum, liquid paraffin (liquid petrolatum), lanolin, cetearyl alcohol (cetyl alcohol 60% and stearyl alcohol 40%), white beeswax, methylparahydroxybenzoate, propylparahydroxybenzoate, purified water.
25 g – jars (1) – cardboard packs.
30 g – jars (1) – cardboard packs.
40 g – jars (1) – cardboard packs.
50 g – jars (1) – cardboard packs.
100 g – jars (1) – cardboard packs.
25 g – aluminum tubes (1) – cardboard packs.
30 g – aluminum tubes (1) – cardboard packs.
40 g – aluminum tubes (1) – cardboard packs.
50 g – aluminum tubes (1) – cardboard packs.
100 g – aluminum tubes (1) – cardboard packs.
Ointment for external use 5%: tubes 25 g, 50 g, or 100 g
Marketing Authorization Holder
Promomed Rus LLC (Russia)
Manufactured By
Biokhimik, JSC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: tubes 25 g, 50 g, or 100 g |
Dosage Form, Packaging, and Composition
Ointment for external use from white with a yellowish tint to light yellow, with a specific smell of lanolin.
| 100 g | |
| Dexpanthenol | 5 g |
Excipients: petrolatum – 38 g, liquid paraffin – 10 g, almond oil – 0.3 g, beeswax (white) – 2.7 g, anhydrous lanolin – 21 g, cetearyl alcohol [cetyl alcohol 60%, stearyl alcohol 40%] (Lanette 0) – 3 g, purified water – 20 g.
25 g – tubes made of combined material with caps (1) – cardboard packs.
50 g – tubes made of combined material with caps (1) – cardboard packs.
100 g – tubes made of combined material with caps (1) – cardboard packs.
Ointment for external use 5%: tubes 25 g or 30 g
Marketing Authorization Holder
Tatkhimpharmpreparaty, JSC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: tubes 25 g or 30 g |
Dosage Form, Packaging, and Composition
| Ointment for external use 5% | 1 g |
| Dexpanthenol | 50 mg |
25 g – aluminum tubes (1) – cardboard packs.
30 g – aluminum tubes (1) – cardboard packs.
Ointment for external use 5%: jars 5 g, 10 g, 15 g, 20 g, 25 g, 30 g, 35 g, 40 g, 50 g, 60 g, 70 g, 80 g, 90 g, or 100 g; tubes 20 g, 25 g, 30 g, 35 g, 40 g, 50 g, 60 g, 70 g, 80 g, 90 g, or 100 g
Marketing Authorization Holder
Tula Pharmaceutical Factory, LLC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: jars 5 g, 10 g, 15 g, 20 g, 25 g, 30 g, 35 g, 40 g, 50 g, 60 g, 70 g, 80 g, 90 g, or 100 g; tubes 20 g, 25 g, 30 g, 35 g, 40 g, 50 g, 60 g, 70 g, 80 g, 90 g, or 100 g |
Dosage Form, Packaging, and Composition
Ointment for external use from white with a yellowish tint to light yellow, homogeneous, with a specific odor.
| 100 g | |
| Dexpanthenol | 5 g |
Excipients: petrolatum – 27 g, liquid paraffin – 10 g, lanolin – 17 g, cholesterol – 0.5 g, isopropyl myristate – 3 g, methylparahydroxybenzoate – 0.07 g, propylparahydroxybenzoate – 0.03 g, water – 37.4 g.
5 g – jars (1) – cardboard packs.
10 g – jars (1) – cardboard packs.
15 g – jars (1) – cardboard packs.
20 g – jars (1) – cardboard packs.
25 g – jars (1) – cardboard packs.
30 g – jars (1) – cardboard packs.
35 g – jars (1) – cardboard packs.
40 g – jars (1) – cardboard packs.
50 g – jars (1) – cardboard packs.
60 g – jars (1) – cardboard packs.
70 g – jars (1) – cardboard packs.
80 g – jars (1) – cardboard packs.
90 g – jars (1) – cardboard packs.
100 g – jars (1) – cardboard packs.
20 g – tubes (1) – cardboard packs.
25 g – tubes (1) – cardboard packs.
30 g – tubes (1) – cardboard packs.
35 g – tubes (1) – cardboard packs.
40 g – tubes (1) – cardboard packs.
50 g – tubes (1) – cardboard packs.
60 g – tubes (1) – cardboard packs.
70 g – tubes (1) – cardboard packs.
80 g – tubes (1) – cardboard packs.
100 g – tubes (1) – cardboard packs.
Ointment for external use 5%: 25 g, 30 g, 40 g, 50 g, or 60 g
Marketing Authorization Holder
Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: 25 g, 30 g, 40 g, 50 g, or 60 g |
Dosage Form, Packaging, and Composition
| Ointment for external use | 100 g |
| Dexpanthenol | 5 g |
25 g – aluminum tubes (1) – cardboard packs.
25 g – jar (1) – cardboard packs.
30 g – aluminum tubes (1) – cardboard packs.
30 g – jar (1) – cardboard packs.
40 g – aluminum tubes (1) – cardboard packs.
50 g – aluminum tubes (1) – cardboard packs.
60 g – aluminum tubes (1) – cardboard packs.
Ointment for external use 5%: tubes 15, 20, 25, 30, 35, 40, 50, 60, 70, 80, 100 g.
Marketing Authorization Holder
Formula-FR, LLC (Russia)
Manufactured By
Tula Pharmaceutical Factory, LLC (Russia)
Dosage Form
|
Dexpanthenol | Ointment for external use 5%: tubes 15, 20, 25, 30, 35, 40, 50, 60, 70, 80, 100 g. |
Dosage Form, Packaging, and Composition
Ointment for external use is homogeneous, from white with a yellowish tint to light yellow in color, with a characteristic odor.
| 100 g | |
| Dexpanthenol | 5 g |
Excipients: petrolatum – 27 g, liquid paraffin – 10 g, lanolin – 17 g, cholesterol – 0.5 g, isopropyl myristate – 3 g, methylparahydroxybenzoate (nipagin, methylparaben) – 0.07 g, propylparahydroxybenzoate (nipasol, propylparaben) – 0.03 g, water – 37.4 g.
15 g – tubes (1) – cardboard packs (1).
20 g – tubes (1) – cardboard packs (1).
25 g – tubes (1) – cardboard packs (1).
30 g – tubes (1) – cardboard packs (1).
35 g – tubes (1) – cardboard packs (1).
40 g – tubes (1) – cardboard packs (1).
50 g – tubes (1) – cardboard packs (1).
60 g – tubes (1) – cardboard packs (1).
70 g – tubes (1) – cardboard packs (1).
80 g – tubes (1) – cardboard packs (1).
100 g – tubes (1) – cardboard packs (1).
Ointment for external use 50 mg/g
Marketing Authorization Holder
Obnovlenie Pfc, JSC (Russia)
Dosage Form
|
Dexpanthenol Renewal | Ointment for external use 50 mg/g |
Dosage Form, Packaging, and Composition
Ointment for external use
| Dexpanthenol | 50 mg/g |
100 g – tubes – cardboard packs – Over-the-counter
25 g – tubes – cardboard packs – Over-the-counter
30 g – jars – cardboard packs – Over-the-counter
30 g – tubes – cardboard packs – Over-the-counter
50 g – jars – cardboard packs – Over-the-counter
50 g – tubes – cardboard packs – Over-the-counter
Ointment for external use 5%: tubes 30 g, 50 g, or 100 g
Marketing Authorization Holder
Vertex, JSC (Russia)
Dosage Form
|
Dexpanthenol-Vertex | Ointment for external use 5%: tubes 30 g, 50 g, or 100 g |
Dosage Form, Packaging, and Composition
Ointment for external use is light yellow in color, homogeneous, with a characteristic odor.
| 1 g | |
| Dexpanthenol | 50 mg |
Excipients: lanolin (anhydrous lanolin), white soft paraffin, liquid paraffin, glycerol (glycerin), stearyl alcohol, cetyl alcohol, sodium citrate dihydrate, citric acid monohydrate, methylparahydroxybenzoate (methylparaben), purified water.
30 g – aluminum tubes (1) – cardboard packs.
50 g – aluminum tubes (1) – cardboard packs.
100 g – aluminum tubes (1) – cardboard packs.
![Dexpanthenol [Ointment, Foam] 1](https://www.medixlife.com/wp-content/uploads/Medixlife_favi_512.png "Dexpanthenol [Ointment, Foam] 2")