Dimebon (Tablets) Instructions for Use

Marketing Authorization Holder

Dimebonet, LLC (Russia)

ATC Code

R06AX (Other systemic antihistamines)

Dosage Form

Dimebon

Tablets 10 mg: 30 pcs.

Dosage Form, Packaging, and Composition

30 pcs. – dark glass jars (1) – cardboard packs.
30 pcs. – blister packs (3) – cardboard packs.

Clinical-Pharmacological Group

Histamine H₁-receptor blocker. Antiallergic drug

Pharmacotherapeutic Group

H1 histamine receptor blocker

Pharmacological Action

It blocks histamine H₁-receptors and partially m-cholino- and serotonin receptors.

It has antihistamine, as well as antiserotonin, m-cholinoblocking, local anesthetic, and sedative effects.

It prevents the development of anaphylactic shock, reduces itching and the severity of local exudative manifestations, and reduces vascular permeability.

The severity of allergic reactions decreases within 2-3 days after administration.

Indications

Allergic diseases of the eyelids, conjunctivitis; pollinosis, urticaria, hay fever, food and cosmetic allergy, drug allergy, angioneurotic edema, atopic dermatitis, diffuse neurodermatitis; allergic and inflammatory eye diseases; burn toxemia; allergic reactions: edema, itching; eczema; reactions associated with insect bites.

ICD codes

Dosage Regimen

Administer orally, regardless of food intake.

For adults, the standard dose is 10 mg to 20 mg taken two to three times daily.

The total daily dose for adults should not exceed 60 mg.

The treatment duration is typically 5 to 12 days, depending on the severity and course of the allergic disease.

For pediatric patients, administer the total daily dose in two or three divided doses.

The daily dose for children up to 1 year is 5 mg to 7.5 mg.

For children aged 1 to 2 years, the daily dose is 5 mg to 15 mg.

For children aged 3 to 5 years, the daily dose is 7.5 mg to 30 mg.

For children over 5 years, the daily dose is 20 mg to 40 mg.

Do not exceed the recommended maximum daily doses for any patient group.

Discontinue treatment if symptoms persist or worsen.

Adverse Reactions

Dry mouth, numbness of the oral mucosa, drowsiness, decreased ability to concentrate.

Contraindications

Hypersensitivity, pregnancy, lactation period.

Use in Pregnancy and Lactation

Use during pregnancy and lactation is possible only for strict indications.

Pediatric Use

Use is possible according to the dosing regimen.

Special Precautions

Use during pregnancy and lactation is possible only for strict indications.

During the treatment period, caution must be exercised when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions (for the duration of taking the drug, such persons should be exempted from work).

Drug Interactions

The depressant effect on the CNS is enhanced with the simultaneous use of hypnotics and anxiolytic drugs (tranquilizers), antidepressants, antipsychotic drugs (neuroleptics), narcotic analgesics.

Storage Conditions

Store at 2°C (36°F) to 30°C (86°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.