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Echinacea (Tablets, Granules, Solution, Juice) Instructions for Use
ATC Code
L03AX (Other immunostimulants)
Active Substance
Echinacea (BP British Pharmacopoeia)
Clinical-Pharmacological Group
Herbal immunostimulant drug
Pharmacotherapeutic Group
Immunostimulating agent of plant origin
Pharmacological Action
A herbal preparation. The herb of Echinacea purpurea contains water-soluble immunostimulating polysaccharides (4-O-methylglucuronylarabinoxylans, acidic arabinorhamno-galactans); essential oils (components include germacrene alcohol, borneol, bornyl acetate, pentadeca-8-en-2-one, germacrene D, caryophyllene, caryophyllene epoxide); flavonoids (ferulic acid and its derivatives, including cichoric acid, methyl ester of cichoric acid, 2-O-caffeoyl-3-O-feruloyl-tartaric acid, 2,3-O-diferuloyl-tartaric acid, 2-O-caffeoyl-tartaric acid); alkamides; polyenes.
It has immunomodulatory and anti-inflammatory effects. Polysaccharides increase the phagocytic activity of neutrophils and macrophages and stimulate the production of interleukin-1. The complex of active substances induces the transformation of B-lymphocytes into plasma cells and improves the function of T-helpers. Due to inulin, levulose, and betaine, it improves metabolic processes, especially in the liver and kidneys. It increases the body’s nonspecific resistance (including to influenza and herpes pathogens). It has a capillary-protective effect.
Indications
Enhancement of nonspecific defense factors of the body in uncomplicated acute infectious diseases and in predisposition to frequent colds; for immune stimulation in patients with uncomplicated acute infectious diseases (as an auxiliary treatment); prevention of ARVI and influenza; as an auxiliary medicinal product during prolonged antibiotic therapy of chronic infectious diseases. Prevention and as part of complex therapy of recurrent infectious diseases of the respiratory tract and urinary tract.
ICD codes
Open the list of ICD codes
| ICD-10 code | Indication |
| J06.9 | Acute upper respiratory infection, unspecified |
| J10 | Influenza due to identified seasonal influenza virus |
| Z29.8 | Other specified prophylactic measures |
| ICD-11 code | Indication |
| 1E30 | Influenza due to identified seasonal influenza virus |
| CA07.0 | Acute upper respiratory tract infection of unspecified site |
| QC05.Z | Prophylactic measures, unspecified |
Dosage Regimen
| The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen. |
Administer Echinacea preparations orally. Strictly adhere to the regimen specific to the prescribed dosage form.
For tablets, take 1-2 tablets three times daily. Swallow whole with water.
For oral solution and juice, administer 2-3 mL three times daily. Use the provided measuring dropper or cup for accurate dosing.
For granules, dissolve 5 granules in the mouth twice daily. Take 20 minutes before or 1 hour after meals.
Initiate treatment at the first sign of illness. For prevention, begin administration during periods of high epidemiological risk.
The standard course of treatment is 10 to 14 days. Do not exceed a continuous treatment duration of 8 weeks.
Allow an interval of at least two weeks before initiating a repeated course. Conduct repeated courses only on the explicit recommendation of a physician.
Adjust the duration of therapy based on clinical response and tolerability. Discontinue use if no improvement is observed within one week.
Adverse Reactions
From the digestive system nausea, vomiting, stool disorders.
From the hematopoietic system:leukopenia (with continuous use for more than 8 weeks).
From the immune system: skin rash, itching, angioneurotic edema, Quincke’s edema, Stevens-Johnson syndrome, anaphylactic shock. Allergic reactions are possible in patients with atopy. A relationship between the occurrence of adverse events and autoimmune diseases (diffuse encephalitis, erythema nodosum, immunothrombocytopenia, Evans syndrome, Sjögren’s syndrome with renal tubular dysfunction) has been reported.
From the cardiovascular system: dizziness, decreased BP.
From the respiratory system bronchospasm with obstruction and attacks of bronchial asthma as manifestations of hypersensitivity reactions.
Allergic reactions hyperemia, edema.
Other chills.
Contraindications
Hypersensitivity to echinacea and plants of the Asteraceae family; progressive systemic and autoimmune diseases (including tuberculosis, sarcoidosis, collagenosis, multiple sclerosis); immunodeficiency (AIDS or HIV infection) and immunosuppression (including cytostatic anticancer therapy; history of organ or bone marrow transplantation); blood diseases (agranulocytosis, leukemia); allergic diseases (urticaria, atopic dermatitis, bronchial asthma); children under 12 years of age; pregnancy, breastfeeding period.
Use in Pregnancy and Lactation
Contraindicated for use during pregnancy and breastfeeding.
Pediatric Use
Contraindicated for use in children under 12 years of age.
Special Precautions
Patients with recurrent infectious diseases of the respiratory tract require regular medical supervision.
Patients with atopy have an increased risk of developing anaphylactic shock.
Drug Interactions
With the simultaneous use of echinacea preparations with immunosuppressants, a mutual weakening of the effect occurs.
Simultaneous use with antibiotics and other antimicrobial agents is possible.
Storage Conditions
Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.
Dispensing Status
Over-the-Counter
Important Safety Information
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.
Medical DisclaimerBrand (or Active Substance), Marketing Authorisation Holder, Dosage Form
Echinacea [Vifitech, CJSC (Russia)]
Tablets 200 mg: 10, 20 or 30 pcs.
Tablets 200 mg: 10, 20 or 30 pcs.
Marketing Authorization Holder
Vifitech, CJSC (Russia)
Dosage Form
 |
Echinacea | Tablets 200 mg: 10, 20 or 30 pcs. |
Dosage Form, Packaging, and Composition
| Tablets | 1 tab. |
| Echinacea purpurea extract | 200 mg |
10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
Echinacea [Homeopathic Pharmacy, LLC (Russia)]
Homeopathic granules: 8 g tubes or jars
Homeopathic granules: 8 g tubes or jars
Marketing Authorization Holder
Homeopathic Pharmacy, LLC (Russia)
Dosage Form
|
Echinacea | Homeopathic granules: 8 g tubes or jars |
Dosage Form, Packaging, and Composition
Homeopathic granules homogeneous, of regular spherical shape, white with a gray or cream tint, odorless.
| 100 g | |
| Echinacea purpurea D3 | 1 g |
Excipients : sugar pellets 100 g.
8 g – polymer tubes (1) – cardboard packs.
8 g – polymer jars (1) – cardboard packs.
Echinacea [PharmVILAR NPO, LLC (Russia)]
Tablets 200 mg: 10, 20, 30, 40, 50, 60, 80, or 100 pcs.
Tablets 200 mg: 10, 20, 30, 40, 50, 60, 80, or 100 pcs.
Marketing Authorization Holder
PharmVILAR NPO, LLC (Russia)
Dosage Form
|
Echinacea | Tablets 200 mg: 10, 20, 30, 40, 50, 60, 80, or 100 pcs. |
Dosage Form, Packaging, and Composition
Tablets round, biconvex, without a score, from light brown to dark brown in color with lighter and darker inclusions.
| 1 tab. | |
| Echinacea dry extract* | 200 mg |
* Echinacea purpurea herb extract (containing a sum of hydroxycinnamic acid derivatives calculated as cichoric acid 7%).
Excipients : lactose monohydrate – 150 mg, potato starch – 40 mg, povidone (low molecular weight medical polyvinylpyrrolidone) – 4 mg, colloidal silicon dioxide – 2 mg, magnesium stearate – 4 mg.
10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (4) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (8) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
30 pcs. – polymer jars (1) – cardboard packs.
60 pcs. – polymer jars (1) – cardboard packs.
100 pcs. – polymer jars (1) – cardboard packs.
Echinacea [Obnovlenie Pfc, JSC (Russia)]
Tablets 200 mg: 30, 60, or 90 pcs.
Tablets 200 mg: 30, 60, or 90 pcs.
Marketing Authorization Holder
Obnovlenie Pfc, JSC (Russia)
Dosage Form
|
Echinacea | Tablets 200 mg: 30, 60, or 90 pcs. |
Dosage Form, Packaging, and Composition
Tablets from grayish-brown with a greenish tint or light brown with a greenish tint to brown in color with lighter and darker inclusions, round, biconvex, with a score.
| 1 tab. | |
| Echinacea purpurea herb extract* | 200 mg |
* Echinacea purpurea herb (Echinaceae purpureae herbae) dry extract, 5:1, corresponding to a sum of hydroxycinnamic acid derivatives calculated as cichoric acid 14 mg**.
** Extractant: water.
Excipients : lactose monohydrate, colloidal silicon dioxide (aerosil), croscarmellose sodium, povidone K-17, magnesium stearate.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (6) – cardboard packs.
10 pcs. – contour cell packs (9) – cardboard packs.
15 pcs. – contour cell packs (2) – cardboard packs.
15 pcs. – contour cell packs (4) – cardboard packs.
15 pcs. – contour cell packs (6) – cardboard packs.
30 pcs. – jars (1) – cardboard packs.
60 pcs. – jars (1) – cardboard packs.
90 pcs. – jars (1) – cardboard packs.
Echinacea Hexal [Dr. Rentschler Arzneimittel, GmbH (Germany)]
Oral solution: bottle 50 ml
Oral solution: bottle 50 ml
Marketing Authorization Holder
Dr. Rentschler Arzneimittel, GmbH (Germany)
For
HEXAL, AG (Germany)
Dosage Form
|
Echinacea Hexal | Oral solution: bottle 50 ml |
Dosage Form, Packaging, and Composition
| Oral solution | 1 bottle |
| Echinacea purpurea herb juice | 50 ml |
50 ml – dark glass bottles (1) complete with a dosing cup – cardboard packs.
Echinacea Hexal [Dr. Rentschler Arzneimittel, GmbH (Germany)]
Oral solution: bottle 100 ml
Oral solution: bottle 100 ml
Marketing Authorization Holder
Dr. Rentschler Arzneimittel, GmbH (Germany)
For
HEXAL, AG (Germany)
Dosage Form
|
Echinacea Hexal | Oral solution: bottle 100 ml |
Dosage Form, Packaging, and Composition
| Oral solution | 1 bottle |
| Echinacea purpurea herb juice | 100 ml |
100 ml – dark glass bottles (1) complete with a dosing cup – cardboard packs.
Echinacea Hexal [Dr. Rentschler Arzneimittel, GmbH (Germany)]
Oral solution: bottle 150 ml
Oral solution: bottle 150 ml
Marketing Authorization Holder
Dr. Rentschler Arzneimittel, GmbH (Germany)
For
HEXAL, AG (Germany)
Dosage Form
|
Echinacea Hexal | Oral solution: bottle 150 ml |
Dosage Form, Packaging, and Composition
| Oral solution | 1 bottle |
| Echinacea purpurea herb juice | 150 ml |
150 ml – dark glass bottles (1) complete with a dosing cup – cardboard packs.
Echinacea Renewal [PFKO-1, LLC (Russia)]
Tablets 200 mg: 30, 60, or 90 pcs.
Tablets 200 mg: 30, 60, or 90 pcs.
Marketing Authorization Holder
PFKO-1, LLC (Russia)
Manufactured By
Obnovlenie Pfc, JSC (Russia)
Dosage Form
|
Echinacea Renewal | Tablets 200 mg: 30, 60, or 90 pcs. |
Dosage Form, Packaging, and Composition
Tablets
| Echinacea purpurea herb extract | 200 mg |
10 pcs. – contour cell packs (3 pcs.) – cardboard packs (30 pcs.) – Over-the-Counter
10 pcs. – contour cell packs (6 pcs.) – cardboard packs (60 pcs.) – Over-the-Counter
10 pcs. – contour cell packs (9 pcs.) – cardboard packs (90 pcs.) – Over-the-Counter
15 pcs. – contour cell packs (2 pcs.) – cardboard packs (30 pcs.) – Over-the-Counter
15 pcs. – contour cell packs (4 pcs.) – cardboard packs (60 pcs.) – Over-the-Counter
15 pcs. – contour cell packs (6 pcs.) – cardboard packs (90 pcs.) – Over-the-Counter
30 pcs. – jars – cardboard packs (30 pcs.) – Over-the-Counter
60 pcs. – jars – cardboard packs (60 pcs.) – Over-the-Counter
90 pcs. – jars – cardboard packs (90 pcs.) – Over-the-Counter
Echinacea Vilar® [Pharmtsentr Vilar JSC (Russia)]
Oral juice: 25 ml, 30 ml, 40 ml, or 50 ml bottle
Oral juice: 25 ml, 30 ml, 40 ml, or 50 ml bottle
Marketing Authorization Holder
Pharmtsentr Vilar JSC (Russia)
Dosage Form
|
Echinacea Vilar® | Oral juice: 25 ml, 30 ml, 40 ml, or 50 ml bottle |
Dosage Form, Packaging, and Composition
| Herbal raw material | 1 bottle |
| Echinacea purpurea liquid extract | 100 % |
50 ml – dark glass bottles (1) – cardboard packs.
50 ml – glass bottles (1) – cardboard packs.
Echinacea-Vilar [Vilar Pez State Unitary Enterprise (Russia)]
Juice: 50 ml bottle
Juice: 50 ml bottle
Marketing Authorization Holder
Vilar Pez State Unitary Enterprise (Russia)
Dosage Form
|
Echinacea-Vilar | Juice: 50 ml bottle |
Dosage Form, Packaging, and Composition
Juice in the form of a transparent reddish-brown liquid, with a specific odor; the presence of a slight sediment is allowed.
| 1 bottle | |
| Echinacea purpurea herb juice* | 50 ml |
Excipients : ethyl alcohol 96%.
* for the preparation of the drug, fresh Echinacea purpurea herb and 96% ethyl alcohol are used.
The content of ethyl alcohol in the drug is about 20%.
50 ml – dark glass bottles (1) – cardboard packs.
![Echinacea [Tablets, Granules, Solution, Juice] 1](https://www.medixlife.com/wp-content/uploads/Medixlife_favi_512.png "Echinacea [Tablets, Granules, Solution, Juice] 2")