Ionoplasm (Solution) Instructions for Use

Marketing Authorization Holder

IST-Pharm, LLC (Russia)

Manufactured By

IST-Pharm, LLC (Russia)

Or

Pharmasintez-Tyumen, LLC (Russia)

ATC Code

B05BB01 (Electrolytes)

Dosage Form

Ionoplasm

Solution for infusion: bottles 250 mL or 500 mL

Dosage Form, Packaging, and Composition

Solution for infusion transparent, from colorless to brownish-yellow.

Excipients : hydrochloric acid solution 1 M or sodium hydroxide solution 1 M – to pH 6.5-8.0, water for injection – up to 1 ml.

250 ml – polyethylene bottles (1) – cardboard boxes.
500 ml – polyethylene bottles (1) – cardboard boxes.

Clinical-Pharmacological Group

Drug for rehydration and detoxification for parenteral use

Pharmacotherapeutic Group

Electrolyte balance restoring agent

Pharmacological Action

A means for rehydration and detoxification. It corrects the acid-base state, replenishes the deficiency of fluid and electrolytes, enhances diuresis, has an antiplatelet property, reduces metabolic acidosis, improves microcirculation, and has a detoxifying, anti-shock effect.

Indications

As a component of infusion therapy as part of complex treatment in adults and children: shock; thermal injury; acute blood loss; hypotonic and isotonic forms of hypohydration and metabolic acidosis in severely ill patients; for the correction of water-salt balance in acute diffuse peritonitis and intestinal obstruction; patients with intestinal fistulas; decompensation of electrolyte disorders; patients with acute intestinal infections; dehydration; metabolic acidosis.

The volemic effect is short-lived; in the treatment of severe hypovolemia, a combination with colloidal solutions, as well as blood and its components, is recommended.

ICD codes

Dosage Regimen

IV, the dose depends on the age, body weight and condition of the patient.

In severe forms of diseases – IV bolus, in mild forms – IV drip.

Before administration, the solution is heated to body temperature. The initial dose is 5-10 drops, then a break is taken for 2-3 minutes to assess the results of the biological test, after which 30 drops are administered, followed by a break for 2-3 minutes. In the absence of individual intolerance, they switch to drip or jet administration in quantities necessary to restore the volume of fluid lost with feces, vomiting, urine, and sweat.

Adverse Reactions

Possible anaphylactoid reactions (tachycardia, decreased blood pressure, itching, skin hyperemia, shortness of breath, hyperthermia), hyperkalemia; allergic reactions.

Contraindications

Hyperkalemia; chronic renal failure; pulmonary edema; chronic heart failure grade II-III; arterial hypertension; hypertensive crisis; traumatic brain injury with increased intracranial pressure.

With caution

Diabetes mellitus (for solution with dextrose).

Use in Renal Impairment

Contraindication — chronic renal failure.

Special Precautions

In patients with renal, cardiac, or hepatic insufficiency, it is necessary to monitor the level of electrolytes in the plasma.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.