Isoniazid (Tablets, Solution) Instructions for Use

Instructions
Dosage forms

ATC Code

J04AC01 (Isoniazid)

Active Substance

Isoniazid (Rec.INN registered by WHO)

Clinical-Pharmacological Group

Antituberculosis drug

Pharmacotherapeutic Group

Agents active against mycobacteria; antituberculosis drugs; hydrazides.

Pharmacological Action

Antituberculosis agent. It exerts a bactericidal effect. Isoniazid is active against extracellular and intracellular Mycobacterium tuberculosis, primarily against actively dividing ones. Its exact mechanism of action is unknown. It is presumed to be associated with the suppression of mycolic acid synthesis, which are components of the mycobacterial cell wall.

Pharmacokinetics

After oral administration, it is rapidly absorbed from the gastrointestinal tract. When taken with food, absorption and bioavailability are reduced. It is widely distributed in all body tissues and fluids, including cerebrospinal, pleural, and ascitic fluids; high concentrations are achieved in lung tissue, kidneys, liver, muscles, saliva, and sputum. Plasma protein binding is very low (0-10%). V_d – 0.57-0.76 L/kg. It is metabolized in the liver. Excreted in the urine, a small amount – in the feces.

It crosses the placental barrier and is excreted in breast milk.

Indications

Treatment and prevention of all forms of tuberculosis caused by M. tuberculosis sensitive to isoniazid, as part of combination therapy.

ICD codes

Open the list of ICD codes

ICD-10 code	Indication
A15	Respiratory tuberculosis, bacteriologically and histologically confirmed
A17	Tuberculosis of nervous system
A18	Tuberculosis of other organs

ICD-11 code	Indication
1B10.0	Respiratory tuberculosis, bacteriologically or histologically confirmed
1B11.Z	Tuberculosis of nervous system, unspecified
1B12	Tuberculosis of other systems and organs

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Administer Isoniazid orally, intramuscularly, intravenously, or intracavitary as directed. Determine the exact dose, route, frequency, and duration of therapy individually based on disease form and severity, patient’s acetylation status, and clinical tolerance.

For active tuberculosis, use Isoniazid only in combination with other antituberculosis agents to prevent rapid development of resistance. The typical adult oral dose is 5 mg/kg per day, up to a maximum of 300 mg daily, administered as a single dose. Alternatively, administer 15 mg/kg, up to 900 mg, two or three times per week under direct observation as part of a supervised intermittent regimen.

For latent tuberculosis infection (LTBI), the standard adult dosage is 300 mg orally as a single daily dose. For children, the dose for LTBI is 10-20 mg/kg per day, up to a maximum of 300 mg daily. The duration of preventive therapy is typically 6 to 9 months, or as recommended by official guidelines.

Calculate the pediatric dosage for active disease based on body weight: 10-15 mg/kg per day, up to a maximum of 300 mg daily. For intermittent therapy in children, administer 20-40 mg/kg per dose, up to 900 mg, two times per week.

Adjust dosage cautiously in patients with renal impairment and monitor for toxicity. In patients with end-stage renal disease, reduce the dose to 200-300 mg daily or 900 mg three times per week after dialysis.

Administer oral doses at least one hour before or two hours after meals to ensure optimal absorption. If gastrointestinal intolerance occurs, administer with food, acknowledging that this may reduce bioavailability.

Concomitantly administer pyridoxine (Vitamin B6), typically 25-50 mg daily, to all patients at high risk for developing peripheral neuropathy, including those who are malnourished, have diabetes, are pregnant or breastfeeding, have HIV infection, have renal failure, or are slow acetylators.

Monitor liver function tests, including ALT and AST, baseline and monthly during treatment. Discontinue therapy immediately if signs of hepatocellular damage appear, such as symptoms of hepatitis or AST/ALT elevations greater than three to five times the upper limit of normal.

Adverse Reactions

From the hematopoietic system: frequency unknown – eosinophilia, bone marrow suppression, granulocytopenia, thrombocytopenia, agranulocytosis, sideroblastic anemia, hemolytic or megaloblastic anemia, pyridoxine-deficiency anemia, coagulopathy, aplastic anemia.

From the immune system: frequency unknown – exanthema (including acneiform, especially in young patients), exfoliative dermatitis, Stevens-Johnson syndrome, photosensitivity, fever, asthma, myalgia and arthralgia, anaphylactic reactions, anaphylactic shock, systemic lupus erythematosus, lupus-like syndrome, lymphadenopathy.

From the endocrine system: frequency unknown – hyperfunction of the adrenal cortex (Cushing’s syndrome) and anterior pituitary lobe (with menstrual cycle disorders in women or gonadotropic disorders/gynecomastia in men) – these phenomena are predominantly reversible.

From metabolism: very rare – hypoglycemia; frequency unknown – hyperglycemia, metabolic acidosis, pellagra (nicotinic acid deficiency).

From the psyche: frequency unknown – mental disorders (irritability, anxiety), decreased concentration, depression, psychoses (manifest, catatonic, or paranoid), euphoria.

From the nervous system: frequent – peripheral polyneuropathy with paresthesia, sensory disturbances, headache, dizziness; frequency unknown – seizures, drowsiness, lethargy, hyperreflexia.

From the organ of vision: rare – optic atrophy; frequency unknown – optic neuritis, diplopia, strabismus.

From the organ of hearing and labyrinthine disorders: frequency unknown – deafness, tinnitus, vertigo (in patients with end-stage renal failure).

From the cardiovascular system: frequency unknown – arrhythmia, vasculitis, increase or decrease in blood pressure.

From the respiratory system: frequency unknown – acute respiratory distress syndrome, interstitial lung disease.

From the digestive system: frequent – diarrhea, constipation, regurgitation, abdominal distension, vomiting; frequency unknown – pancreatitis, dry mouth.

From the liver and biliary tract: very common – increased activity of hepatic transaminases; infrequent – hepatitis; frequency unknown – acute liver failure, liver damage, jaundice, acute hepatitis (including fatal cases).

From the musculoskeletal system: frequent – muscle tremor; frequency unknown – rheumatic syndrome, rhabdomyolysis.

From the urinary system: frequency unknown – glomerulonephritis (mainly reversible), dysuria.

From the skin and subcutaneous tissues: rare – toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms (DRESS syndrome).

Contraindications

Hypersensitivity to isoniazid; drug-induced hepatitis and/or other severe adverse reactions that developed during previous treatment with isoniazid; liver disease in the acute stage; severe hepatic insufficiency; children under 3 years of age (for oral administration).

With caution: alcoholism, mild and moderate hepatic insufficiency, history of liver dysfunction or chronic liver dysfunction, renal failure, convulsive seizures, age over 35 years, long-term use of other potentially hepatotoxic drugs, history of isoniazid therapy discontinuation, peripheral neuropathy, HIV infection, decompensated cardiovascular diseases (chronic heart failure, angina pectoris, arterial hypertension), hypothyroidism, diabetes mellitus, exhaustion, history of mental illness, “slow acetylators”, female sex, pregnancy (for parenteral administration).

Use in Pregnancy and Lactation

Isoniazid crosses the placenta. During pregnancy, it should be used only in cases where the intended benefit to the mother outweighs the potential risk to the fetus.

Isoniazid crosses the placental barrier and is excreted in breast milk. If use during lactation is necessary, the issue of discontinuing breastfeeding should be considered.

Use in Hepatic Impairment

The use of isoniazid is contraindicated in patients with severe hepatic insufficiency, with liver diseases in the acute stage.

It should be prescribed with caution to patients with mild and moderate hepatic impairment; strict monitoring of liver enzymes is necessary.

Use in Renal Impairment

Use with caution in patients with renal failure.

Pediatric Use

Isoniazid is contraindicated for oral administration in children under 3 years of age.

Geriatric Use

It should be used with caution in elderly patients.

Special Precautions

To avoid the rapid development of resistance of Mycobacterium tuberculosis, Isoniazid is used in combination with other antituberculosis drugs.

In some cases, fatal drug-induced hepatitis develops during treatment with isoniazid, which can occur even several months after discontinuation of use. The risk increases with age (highest frequency in the age group 35-64 years), especially with daily ethanol consumption. Therefore, liver function should be monitored monthly in all patients; in persons over 35 years of age, liver function is additionally examined before starting treatment. If ALT, AST activity increases by 4 times or more, or the concentration of bilirubin in the blood increases, isoniazid treatment should be discontinued.

To reduce side effects, pyridoxine (orally or intramuscularly), or glutamic acid (orally), or thiamine (intramuscularly) is prescribed simultaneously with isoniazid.

It should be taken into account that Isoniazid is metabolized in the liver by acetylation to inactive metabolites. The degree of acetylation is determined by genetic factors. Due to the varying degree of metabolism, it is advisable to determine the rate of its inactivation by the content of the active substance in the blood and urine before using isoniazid. In patients who exhibit rapid inactivation, Isoniazid is used in higher doses.

During treatment with isoniazid, consumption of cheese (especially Swiss or Cheshire), fish (especially tuna, sardine) should be avoided, since when consumed simultaneously with isoniazid, reactions may occur (skin hyperemia, itching, sensation of heat or cold, palpitations, increased sweating, chills, headache, dizziness) associated with suppression of MAO and DAO activity and leading to impaired metabolism of tyramine and histamine contained in fish and cheese. It should be borne in mind that Isoniazid can cause hyperglycemia with secondary glucosuria; tests with copper ion reduction may be false-positive; it does not affect enzymatic tests for glucose. Simultaneous consumption of alcohol contributes to increased hepatotoxic reactions.

Patients with intolerance to ethionamide, pyrazinamide, nicotinic acid or other chemically similar substances may have intolerance to isoniazid. Laboratory parameters of ALT and AST, serum bilirubin concentration may transiently increase without clinical manifestations.

After injection, the patient must observe bed rest for 1-1.5 hours.

Effect on ability to drive vehicles and mechanisms

During the treatment period, patients should avoid driving vehicles and other activities requiring high concentration and speed of psychomotor reactions, due to the possibility of developing adverse reactions from the nervous system.

Drug Interactions

Isoniazid inhibits the CYP2C19, CYP1A2, CYP2A6, CYP2E1, and CYP3A isoenzymes of the hepatic cytochrome P450 system, which may lead to slowed elimination of drugs metabolized by these enzymes.

In “slow acetylators” and in patients simultaneously receiving aminosalicylic acid, tissue concentrations of isoniazid may be increased and the frequency of side effects may be increased.

Prednisolone can significantly reduce the plasma concentration of isoniazid. Antacid drugs (especially aluminum-containing ones) slow down absorption and reduce the concentration of isoniazid in the blood (antacids should be taken no earlier than 1 hour after taking isoniazid).

Isoniazid increases the frequency and severity of liver function disorders in combination with rifampicin in patients with pre-existing liver diseases.

Isoniazid increases the blood concentration of phenytoin, enhancing its side effects such as drowsiness and ataxia, reduces the effectiveness of oral combined contraceptive drugs, glipizide, tolbutamide, tolazamide, thiamine; suppresses the elimination of triazolam; reduces the content of zinc ions in the blood. Isoniazid enhances the effect of coumarin derivatives, indandione, benzodiazepines, carbamazepine, theophylline, as it reduces their metabolism.

Isoniazid increases the blood concentration of valproic acid (monitoring of valproic acid concentration is necessary: adjustment of the dosage regimen may be required).

When isoniazid is combined with paracetamol, hepatotoxicity and nephrotoxicity increase.

Isoniazid reduces metabolic transformations and increases the blood concentration of alfentanil.

Cycloserine and disulfiram enhance the adverse central effects of isoniazid.

The combination of isoniazid with pyridoxine reduces the risk of developing peripheral neuritis.

Isoniazid should be combined with caution with potentially neuro-, hepato-, and nephrotoxic drugs due to the risk of increased side effects.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Isoniazid tablets [As-Pharm OJSC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.
Tablets 200 mg: 10, 20 or 100 pcs.
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

As-Pharm OJSC (Russia)

Dosage Forms

	Isoniazid tablets	Tablets 100 mg: 10, 20 or 100 pcs.
		Tablets 200 mg: 10, 20 or 100 pcs.
		Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [AsPharma LLC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.
Tablets 200 mg: 10, 20 or 100 pcs.
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

AsPharma LLC (Russia)

Dosage Forms

	Isoniazid tablets	Tablets 100 mg: 10, 20 or 100 pcs.
		Tablets 200 mg: 10, 20 or 100 pcs.
		Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Bioreactor, LLC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.
Tablets 200 mg: 10, 20 or 100 pcs.
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Bioreactor, LLC (Russia)

Dosage Forms

	Isoniazid tablets	Tablets 100 mg: 10, 20 or 100 pcs.
		Tablets 200 mg: 10, 20 or 100 pcs.
		Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – blister packs.
10 pcs. – blister packs (2) – cardboard packs.
10 pcs. – blister packs (10) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Biopharma, CJS (Russia)]
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Biopharma, CJS (Russia)

Dosage Form

Isoniazid tablets

Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Biopharma, CJS (Russia)]
Tablets 200 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Biopharma, CJS (Russia)

Dosage Form

Isoniazid tablets

Tablets 200 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Dalkhimpharm, JSC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Dalkhimpharm, JSC (Russia)]
Tablets 200 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 200 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Dalkhimpharm, JSC (Russia)]
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [RosMedPreparaty, CJS (Russia)]
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

RosMedPreparaty, CJS (Russia)

Dosage Form

Isoniazid tablets

Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [RosMedPreparaty, CJS (Russia)]
Tablets 200 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

RosMedPreparaty, CJS (Russia)

Dosage Form

Isoniazid tablets

Tablets 200 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [RosMedPreparaty, CJS (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

RosMedPreparaty, CJS (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Severnaya Zvezda, CJSC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Severnaya Zvezda, CJSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Severnaya Zvezda, CJSC (Russia)]
Tablets 200 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Severnaya Zvezda, CJSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 200 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Severnaya Zvezda, CJSC (Russia)]
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Severnaya Zvezda, CJSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Tatkhimpharmpreparaty, JSC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Tatkhimpharmpreparaty, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Tatkhimpharmpreparaty, JSC (Russia)]
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Tatkhimpharmpreparaty, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Tatkhimpharmpreparaty, JSC (Russia)]
Tablets 200 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Tatkhimpharmpreparaty, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 200 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Tatkhimpharmpreparaty, JSC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Tatkhimpharmpreparaty, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)]
Tablets 200 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 200 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)]
Tablets 300 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 300 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Combine, JSC (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

10 pcs. – contour cell packs (10) – cardboard packs.

100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid tablets [Farkos NPF, LLC (Russia)]
Tablets 100 mg: 10, 20 or 100 pcs.

Marketing Authorization Holder

Farkos NPF, LLC (Russia)

Dosage Form

Isoniazid tablets

Tablets 100 mg: 10, 20 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packs.

10 pcs. – contour cell packs (2) – cardboard packs.

Tablets	1 tab.
Isoniazid	200 mg

Isoniazid [Biosintez, PJSC (Russia)]
Tablets 300 mg: 20, 50, or 100 pcs.

Marketing Authorization Holder

Biosintez, PJSC (Russia)

Dosage Form

Isoniazid

Tablets 300 mg: 20, 50, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

Isoniazid [Biosintez, PJSC (Russia)]
Solution for injection 10% (500 mg/5 ml): amp. 10 pcs.

Marketing Authorization Holder

Biosintez, PJSC (Russia)

Dosage Form

Isoniazid

Solution for injection 10% (500 mg/5 ml): amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for injection 10%	1 ml	1 amp.
Isoniazid	100 mg	500 mg

5 ml – ampoules (5) – contour cell packs (2) – cardboard packs.

Isoniazid [Dalkhimpharm, JSC (Russia)]
Solution for injection 100 mg/ml: amp. 10 pcs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Isoniazid

Solution for injection 100 mg/ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Solution for injection as a clear, slightly colored liquid.

	1 ml
Isoniazid	100 mg

Excipients: water for injections – up to 1 ml.

5 ml – ampoules (5) – contour cell packs (2) – cardboard packs.
5 ml – ampoules (10) – cardboard boxes.

Isoniazid [Dalkhimpharm, JSC (Russia)]
Tablets 100 mg: 20, 50, or 100 pcs.
Tablets 200 mg: 20 or 50 pcs.
Tablets 300 mg: 20, 30, or 50 pcs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Forms

	Isoniazid	Tablets 100 mg: 20, 50, or 100 pcs.
		Tablets 200 mg: 20 or 50 pcs.
		Tablets 300 mg: 20, 30, or 50 pcs.

Dosage Form, Packaging, and Composition

Tablets white or white with a yellowish tint, flat-cylindrical in shape, with a bevel.

	1 tab.
Isoniazid	100 mg

Excipients: potato starch – 8.9 mg, calcium stearate – 1.1 mg.

10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
50 pcs. – polymer jars (1) – cardboard packs.
100 pcs. – polymer jars (1) – cardboard packs.

Tablets white or white with a yellowish tint, flat-cylindrical in shape, with a bevel and a score.

	1 tab.
Isoniazid	200 mg

Excipients: potato starch – 17.8 mg, calcium stearate – 2.2 mg.

10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
50 pcs. – polymer jars (1) – cardboard packs.

Tablets white or white with a yellowish tint, flat-cylindrical in shape, with a bevel and a score.

	1 tab.
Isoniazid	300 mg

Tablets	1 tab.
Isoniazid	300 mg

Isoniazid [Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)]
Tablets 100 mg: 10, 20, 30, 50, 60, or 100 pcs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Isoniazid

Tablets 100 mg: 10, 20, 30, 50, 60, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets white or almost white, round, flat-cylindrical, with a bevel.

	1 tab.
Isoniazid	100 mg

Excipients: calcium stearate – 1.1 mg, crospovidone – 1.1 mg, potato starch – 7.8 mg.

Nominal tablet weight 110 mg.

10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
10 pcs. – contour cell packs (6) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
10 pcs. – contour non-cell packs (1) – cardboard packs.
10 pcs. – contour non-cell packs (2) – cardboard packs.
10 pcs. – contour non-cell packs (3) – cardboard packs.
10 pcs. – contour non-cell packs (5) – cardboard packs.
10 pcs. – contour non-cell packs (6) – cardboard packs.
10 pcs. – contour non-cell packs (10) – cardboard packs.
50 pcs. – jars (1) – cardboard packs.
60 pcs. – jars (1) – cardboard packs.
100 pcs. – jars (1) – cardboard packs.

Isoniazid [Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)]
Tablets 200 mg: 10, 20, 30, 50, 60, or 100 pcs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Isoniazid

Tablets 200 mg: 10, 20, 30, 50, 60, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets white or almost white, round, flat-cylindrical, with a bevel and a score line.

	1 tab.
Isoniazid	200 mg

Excipients: calcium stearate – 2.2 mg, crospovidone – 2.2 mg, potato starch – 15.6 mg.

Nominal tablet mass 220 mg.

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.
10 pcs. – contour cell packaging (3) – cardboard packs.
10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (6) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.
10 pcs. – contour non-cell packaging (1) – cardboard packs.
10 pcs. – contour non-cell packaging (2) – cardboard packs.
10 pcs. – contour non-cell packaging (3) – cardboard packs.
10 pcs. – contour non-cell packaging (5) – cardboard packs.
10 pcs. – contour non-cell packaging (6) – cardboard packs.
10 pcs. – contour non-cell packaging (10) – cardboard packs.
50 pcs. – jars (1) – cardboard packs.
60 pcs. – jars (1) – cardboard packs.
100 pcs. – jars (1) – cardboard packs.

Isoniazid [Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)]
Tablets 300 mg: 10, 20, 30, 50, 60, or 100 pcs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Isoniazid

Tablets 300 mg: 10, 20, 30, 50, 60, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets white or almost white, round, flat-cylindrical, with a bevel and a score line.

	1 tab.
Isoniazid	300 mg

Excipients: calcium stearate – 3.3 mg, crospovidone – 3.3 mg, potato starch – 23.4 mg.

Nominal tablet mass 330 mg.

Isoniazid [Pharmasintez, JSC (Russia)]
Tablets 300 mg: 100, 500 or 1000 pcs.

Marketing Authorization Holder

Pharmasintez, JSC (Russia)

Dosage Form

Isoniazid

Tablets 300 mg: 100, 500 or 1000 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

Tablets	1 tab.
Isoniazid	200 mg

10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.
100 pcs. – polymer jars.
500 pcs. – polymer jars.
1000 pcs. – polymer jars.
100 pcs. – polypropylene jars.
500 pcs. – polypropylene jars.
1000 pcs. – polypropylene jars.

Isoniazid [Pharmconcept, LLC (Russia)]
Tablets 100 mg: 20, 50, or 100 pcs.
Tablets 150 mg: 20, 50, or 100 pcs.
Tablets 200 mg: 20, 50, or 100 pcs.
Tablets 300 mg: 20, 50, or 100 pcs.

Marketing Authorization Holder

Pharmconcept, LLC (Russia)

Dosage Forms

	Isoniazid	Tablets 100 mg: 20, 50, or 100 pcs.
		Tablets 150 mg: 20, 50, or 100 pcs.
		Tablets 200 mg: 20, 50, or 100 pcs.
		Tablets 300 mg: 20, 50, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets white or white with a yellowish tint, round, flat-cylindrical, with beveled edges; slight marbling is allowed.

	1 tab.
Isoniazid	100 mg

Excipients: potato starch – 4.9 mg, povidone K30 – 4 mg, magnesium stearate – 1.1 mg.

10 pcs. – contour cell packaging (2) – cardboard packs.
10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.

Tablets white or white with a yellowish tint, round, flat-cylindrical, with beveled edges; slight marbling is allowed.

	1 tab.
Isoniazid	150 mg

Excipients: potato starch – 7.35 mg, povidone K30 – 6 mg, magnesium stearate – 1.65 mg.

10 pcs. – contour cell packaging (2) – cardboard packs.
10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.

Tablets white or white with a yellowish tint, round, flat-cylindrical, with beveled edges; slight marbling is allowed.

	1 tab.
Isoniazid	200 mg

Excipients: potato starch – 9.8 mg, povidone K30 – 8 mg, magnesium stearate – 2.2 mg.

10 pcs. – contour cell packaging (2) – cardboard packs.
10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.

Tablets white or white with a yellowish tint, round, flat-cylindrical, with beveled edges; slight marbling is allowed, with a score line on one side.

	1 tab.
Isoniazid	300 mg

Excipients: potato starch – 14.7 mg, povidone K30 – 12 mg, magnesium stearate – 3.3 mg.

10 pcs. – contour cell packaging (2) – cardboard packs.
10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.

Isoniazid [Akrikhin Chemical and Pharmaceutical Plant, JSC (Russia)]
Tablets 300 mg: 50 or 100 pcs.

Marketing Authorization Holder

Akrikhin Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Isoniazid

Tablets 300 mg: 50 or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – contour cell packaging (10) – cardboard packs.
50 pcs. – polyethylene blisters (1) – cardboard packs.
100 pcs. – dark glass jars (1) – cardboard packs.

Isoniazid Pharmasyntez [Pharmasintez, JSC (Russia)]
Tablets 300 mg

Marketing Authorization Holder

Pharmasintez, JSC (Russia)

Dosage Form

Isoniazid Pharmasyntez

Tablets 300 mg

Dosage Form, Packaging, and Composition

Tablets

	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packaging (10 pcs.) – cardboard packs (100 pcs.) – By prescription
100 pcs. – jars 1-150 pcs. – cardboard boxes (100 pcs.) – for hospitals
1000 pcs. – jars 1-150 pcs. – cardboard boxes (1000 pcs.) – for hospitals
30 pcs. – jars 1-150 pcs. – cardboard boxes (30 pcs.) – for hospitals
500 pcs. – jars 1-150 pcs. – cardboard boxes (500 pcs.) – for hospitals

Isoniazid Pharmasyntez [Pharmasintez, JSC (Russia)]
Tablets 100 mg
Tablets 150 mg
Tablets 200 mg

Marketing Authorization Holder

Pharmasintez, JSC (Russia)

Dosage Forms

	Isoniazid Pharmasyntez	Tablets 100 mg
		Tablets 150 mg
		Tablets 200 mg

Dosage Form, Packaging, and Composition

Tablets

	1 tab.
Isoniazid	100 mg

10 pcs. – contour cell packaging (10 pcs.) – cardboard packs (100 pcs.) – By prescription
10 pcs. – contour cell packaging (5 pcs.) – cardboard packs (50 pcs.) – By prescription
100 pcs. – jars 1-150 pcs. – cardboard boxes (100 pcs.) – for hospitals
1000 pcs. – jars 1-150 pcs. – cardboard boxes (1000 pcs.) – for hospitals
30 pcs. – jars 1-150 pcs. – cardboard boxes (30 pcs.) – for hospitals
500 pcs. – jars 1-150 pcs. – cardboard boxes (500 pcs.) – for hospitals

Tablets

	1 tab.
Isoniazid	150 mg

Tablets

	1 tab.
Isoniazid	200 mg

Isoniazid solution for injections 10% [Biokhimik, JSC (Russia)]
Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Marketing Authorization Holder

Biokhimik, JSC (Russia)

Dosage Form

Isoniazid solution for injections 10%

Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration	1 ml	1 amp.
Isoniazid	100 mg	500 mg

5 ml – ampoules (5) – contour cell packaging (1) – cardboard packs.
5 ml – ampoules (5) – contour cell packaging (2) – cardboard packs.
5 ml – ampoules (10) – cardboard packs.

Isoniazid solution for injections 10% [Dalkhimpharm, JSC (Russia)]
Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Marketing Authorization Holder

Dalkhimpharm, JSC (Russia)

Dosage Form

Isoniazid solution for injections 10%

Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration	1 ml	1 amp.
Isoniazid	100 mg	500 mg

5 ml – ampoules (5) – contour cell packaging (1) – cardboard packs.
5 ml – ampoules (5) – contour cell packaging (2) – cardboard packs.
5 ml – ampoules (10) – cardboard packs.

Isoniazid solution for injections 10% [Sintez PJSC (Russia)]
Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Marketing Authorization Holder

Sintez PJSC (Russia)

Dosage Form

Isoniazid solution for injections 10%

Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration	1 ml	1 amp.
Isoniazid	100 mg	500 mg

5 ml – ampoules (5) – contour cell packaging (1) – cardboard packs.
5 ml – ampoules (5) – contour cell packaging (2) – cardboard packs.
5 ml – ampoules (10) – cardboard packs.

Isoniazid solution for injections 10% [Pharmstandard-Ufimsky Vitaminny Zavod OJSC (Russia)]
Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Marketing Authorization Holder

Pharmstandard-Ufimsky Vitaminny Zavod OJSC (Russia)

Dosage Form

Isoniazid solution for injection 10%

Solution for intravenous and intramuscular administration 500 mg/5 ml: amp. 5 or 10 pcs.

Dosage Form, Packaging, and Composition

Solution for intravenous and intramuscular administration	1 ml	1 amp.
Isoniazid	100 mg	500 mg

5 ml – ampoules (5) – contour cell packs (1) – cardboard packs.
5 ml – ampoules (5) – contour cell packs (2) – cardboard packs.
5 ml – ampoules (10) – cardboard packs.

Isoniazid-AKOS [Sintez PJSC (Russia)]
Tablets 300 mg: 100 pcs.

Marketing Authorization Holder

Sintez PJSC (Russia)

Dosage Form

Isoniazid-AKOS

Tablets 300 mg: 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Isoniazid	300 mg

10 pcs. – contour cell packs (10) – cardboard packs.
100 pcs. – jars (1) – cardboard packs.

Isoniazid-Darnitsa [Darnitsa Pharmaceutical Firm, PJSC (Ukraine)]
Injection solution 500 mg/5 ml: amp. 10 pcs.

Marketing Authorization Holder

Darnitsa Pharmaceutical Firm, PJSC (Ukraine)

Dosage Form

Isoniazid-Darnitsa

Injection solution 500 mg/5 ml: amp. 10 pcs.

Dosage Form, Packaging, and Composition

Injection solution	1 ml	1 amp.
Isoniazid	100 mg	500 mg

5 ml – ampoules (10) – cardboard packs.

Isoniazid-Edvansd [Advanced Pharma, LLC (Russia)]
Tablets 100 mg: 10, 20, 30, 50, 60, or 100 pcs.
Tablets 200 mg: 10, 20, 30, 50, 60, or 100 pcs.
Tablets 300 mg: 10, 20, 30, 50, 60, or 100 pcs.

Marketing Authorization Holder

Advanced Pharma, LLC (Russia)

Dosage Forms

	Isoniazid-Edvansd	Tablets 100 mg: 10, 20, 30, 50, 60, or 100 pcs.
		Tablets 200 mg: 10, 20, 30, 50, 60, or 100 pcs.
		Tablets 300 mg: 10, 20, 30, 50, 60, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets white or almost white, round, biconvex, with a score.

	1 tab.
Isoniazid	100 mg

Excipients : potato starch – 3.4 mg, povidone K30 – 4.4 mg, crospovidone XL-10 – 1.1 mg, magnesium stearate – 1.1 mg.

10 pcs. – blisters – cardboard packs.
10 pcs. – blisters (2) – cardboard packs.
10 pcs. – blisters (3) – cardboard packs.
10 pcs. – blisters (5) – cardboard packs.
10 pcs. – blisters (6) – cardboard packs.
10 pcs. – blisters (10) – cardboard packs.
10 pcs. – strips – cardboard packs.
10 pcs. – strips (2) – cardboard packs.
10 pcs. – strips (3) – cardboard packs.
10 pcs. – strips (5) – cardboard packs.
10 pcs. – strips (6) – cardboard packs.
10 pcs. – strips (10) – cardboard packs.
30 pcs. – jars – cardboard packs.
50 pcs. – jars – cardboard packs.
60 pcs. – jars – cardboard packs.
100 pcs. – jars – cardboard packs.

Tablets white or almost white, round, flat-cylindrical, with a score.

	1 tab.
Isoniazid	200 mg

Excipients : potato starch – 6.8 mg, povidone K30 – 8.8 mg, crospovidone XL-10 – 2.2 mg, magnesium stearate – 2.2 mg.

Tablets white or almost white, round, flat-cylindrical, with a score.

	1 tab.
Isoniazid	300 mg

Excipients : potato starch – 10.2 mg, povidone K30 – 13.2 mg, crospovidone XL-10 – 3.3 mg, magnesium stearate – 3.3 mg.

Isoniazid-Ferain [Bryntsalov-A, JSC (Russia)]
Solution for injection 100 mg/ml: 5 ml amp. 10, 50, 100, 125, 250, 500, or 1000 pcs.

Marketing Authorization Holder

Bryntsalov-A, JSC (Russia)

Dosage Form

Isoniazid-Ferain

Solution for injection 100 mg/ml: 5 ml amp. 10, 50, 100, 125, 250, 500, or 1000 pcs.

Dosage Form, Packaging, and Composition

Injection solution transparent, colorless or slightly colored.

	1 ml
Isoniazid	100 mg

Excipients : water for injections up to 1 ml.

5 ml – ampoules (5) – contour cell packs (1) – cardboard packs.
5 ml – ampoules (5) – contour cell packs (2) – cardboard packs.
5 ml – ampoules (5) – contour cell packs (10) – cardboard boxes.
5 ml – ampoules (5) – contour cell packs (20) – cardboard boxes.
5 ml – ampoules (5) – contour cell packs (25) – cardboard boxes.
5 ml – ampoules (5) – contour cell packs (50) – cardboard boxes.
5 ml – ampoules (5) – contour cell packs (100) – cardboard boxes.
5 ml – ampoules (5) – contour cell packs (200) – cardboard boxes.

Medixlife (Author)

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