Novocaine 0.66 G, furacillin 0.066 G, ethanol 70% to 100 ML (Solution) Instructions for Use

Marketing Authorization Holder

Vladivostok Pharmaceutical Factory, JSC (Russia)

ATC Code

D08AF (Nitrofuran derivatives)

Active Substances

Procaine (Rec.INN registered by WHO)

Nitrofural (Rec.INN registered by WHO)

Dosage Form

Novocaine 0.66 G, furacillin 0.066 G, ethanol 70% to 100 ML

Solution for external use (alcoholic)

Dosage Form, Packaging, and Composition

Solution for external use (alcoholic)

Excipients : ethanol 70% – up to 100 ml.

Clinical-Pharmacological Group

Drug with antimicrobial and local anesthetic action for external and topical use

Pharmacotherapeutic Group

Antiseptic

Pharmacological Action

A combined agent that has antiseptic, antimicrobial, and local anesthetic effects.

Indications

Apply the solution for the treatment of infected skin lesions and wounds requiring antimicrobial action and local anesthesia.

• Infected wounds, including post-traumatic wound infections.
• Trophic ulcers and chronic skin ulcers of various etiologies.
• Burns of varying severity to prevent and treat bacterial contamination.
• Decubitus ulcers (bedsores) for cleansing and pain relief.

ICD codes

Dosage Regimen

Use externally only. Do not ingest or apply to mucous membranes.

Apply the solution to the affected skin areas using a sterile gauze pad or by irrigation. Use 2 to 3 times daily, or as directed by a physician. The duration of treatment depends on the severity of the condition and the healing rate.

Avoid contact with eyes. In case of accidental contact, rinse thoroughly with copious amounts of water.

Adverse Reactions

Monitor the application site for signs of local intolerance.

Allergic reactions are possible, including skin rash, itching, redness, and urticaria. Discontinue use immediately if any signs of hypersensitivity appear.

Local reactions, such as transient burning or irritation, may occur, especially on denuded skin or severe burns.

Drug Interactions

No specific drug interactions for external use are well-documented.

Exercise caution with concurrent use of other topical preparations on the same area to avoid physical or chemical incompatibility.

The systemic absorption of procaine is minimal with correct external application, making systemic interactions unlikely.

Contraindications

Do not use this solution under any circumstances if the patient has a known hypersensitivity to any of its components.

• Hypersensitivity to procaine (novocaine) or other ester-type local anesthetics.
• Hypersensitivity to nitrofural (furacillin) or other nitrofuran derivatives.
• Known allergic reaction to any of the excipients, including ethanol.
• Do not apply to extensively denuded skin surfaces or severe burns covering a large body surface area due to increased risk of systemic absorption and adverse effects.

Overdose

Overdose is unlikely with correct external use due to limited systemic absorption.

Symptoms of systemic procaine toxicity (CNS effects, cardiovascular collapse) could theoretically occur with application to extensive, severely damaged skin or mucous membranes.

In case of accidental ingestion, seek immediate medical attention. Symptoms may include dizziness, nausea, and convulsions. Treatment is symptomatic and supportive.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.