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Pikovit® (Tablets, Syrup) Instructions for Use

ATC Code

A11BA (Multivitamins)

Clinical-Pharmacological Group

Multivitamins

Pharmacotherapeutic Group

Multivitamin agent

Pharmacological Action

A polyvitamin medicinal product. It contains a complex of vitamins that are important factors in metabolic processes in the body.

Retinol (vitamin A) is involved in the synthesis of various substances (proteins, lipids, mucopolysaccharides) and ensures the normal function of the skin, mucous membranes, and the organ of vision.

Colecalciferol (vitamin D3) plays an important role in maintaining the balance of calcium and phosphorus in the body. Its deficiency reduces the calcium content in bone tissue (osteoporosis).

Thiamine (vitamin B1) normalizes heart activity and promotes the normal functioning of the nervous system.

Riboflavin (vitamin B2) promotes tissue regeneration, including skin cells.

Pyridoxine (vitamin B6) helps maintain the structure and function of bones, teeth, and gums; it affects erythropoiesis and promotes the normal functioning of the nervous system.

Cyanocobalamin (vitamin B12) is involved in erythropoiesis and promotes the normal functioning of the nervous system.

B vitamins are involved in the formation of various enzymes that regulate metabolism in the body.

Ascorbic acid (vitamin C) is involved in the oxidation of a number of biologically active substances, the regulation of metabolism in connective tissue, carbohydrate metabolism, blood clotting, and tissue regeneration; it stimulates the formation of steroid hormones and normalizes capillary permeability. Vitamin C increases the body’s resistance to infections and reduces inflammatory reactions.

Nicotinamide (vitamin PP) and D-panthenol (vitamin B5) are coenzymes involved in protein metabolism, the synthesis of fatty acids and cholesterol, energy production, and are necessary for the normal functioning of the central nervous system.

Indications

Used in children as a prophylactic agent in conditions accompanied by an increased need for vitamins: fatigue in school-age children; increased physical and neuropsychic stress; in the absence of appetite and irregular, inadequate, or monotonous diet; during the recovery period after past illnesses, to increase the body’s resistance to infectious and colds. As part of complex therapy when using chemotherapeutic agents.

ICD codes

ICD-10 code Indication
E50-E64 Other types of nutritional deficiencies (E50-E64)
E63.1 Disparate intake of food elements
Z54 Convalescence
Z73.0 Burn-out
Z73.3 Stress, not elsewhere classified (physical and mental strain)
ICD-11 code Indication
5B7Z Malnutrition, unspecified
QB7Z Convalescence, unspecified
QD85 Burn-out
QE01 Stress, not elsewhere classified

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Administer orally with a sufficient amount of fluid. Adhere strictly to the age-specific dosage to prevent hypervitaminosis.

For Pikovit® Tablets: Children from 4 to 6 years old take one tablet four to five times daily. Children from 7 to 14 years old take one tablet five to seven times daily. Suck or chew the tablets slowly.

For Pikovit® Syrup: Children from 1 to 3 years old take one teaspoon (5 ml) twice daily. Children from 4 to 6 years old take one teaspoon (5 ml) three times daily. Children from 7 to 14 years old take one teaspoon (5 ml) three to four times daily. Use the measuring spoon provided.

Take the medication during or immediately after a meal to improve gastrointestinal tolerance. The treatment course is typically 20-30 days. Repeat courses 2-3 times per year or as directed by a physician.

Do not exceed the recommended daily dose. The regimen may be adjusted individually based on clinical indications, nutritional status, and the patient’s overall condition.

Adverse Reactions

From the digestive system diarrhea.

From the nervous system headache.

Other allergic reactions, anaphylactic shock.

Contraindications

Hypervitaminosis A and D; hypersensitivity to the components of the drug.

Special Precautions

During use, urine may turn yellow, which has no clinical significance and is explained by the presence of riboflavin in the preparation.

It is not recommended to take it simultaneously with other preparations containing vitamins.

Drug Interactions

Vitamin C enhances the action and side effects of antimicrobial agents from the sulfonamides group (including the appearance of crystals in the urine).

It should not be taken simultaneously with tetracycline series drugs and sodium fluoride, because calcium reduces the absorption of these drugs. If it is necessary to use this combination with tetracycline antibiotics and sodium fluoride, the interval between taking these drugs should be at least 3 hours.

Pyridoxine inhibits the activity of levodopa.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Marketing Authorization Holder

Krka d.d., Novo mesto (Slovenia)

Dosage Form

Bottle OTC Icon Pikovit® Coated tablets: 30 or 60 pcs.

Dosage Form, Packaging, and Composition

Coated tablets of intense pink, yellow, green, and orange color, round, biconvex; inclusions are allowed.

1 tab.
Retinyl palmitate concentrate1) 0.35 mg
Colecalciferol concentrate2) 0.08 mg
Ascorbic acid 10 mg
Thiamine mononitrate 0.25 mg
Riboflavin 0.3 mg
Pyridoxine hydrochloride 0.3 mg
Cyanocobalamin in mannitol (E421) 0.2 mg
Nicotinamide 3 mg
Folic acid3) 0.04 mg
Calcium pantothenate 1.2 mg
Calcium Hydrogen Phosphate 43 mg

1) Retinyl palmitate concentrate, synthetic, oil form (1.7 MIU/g) 0.35 mg contains: retinyl palmitate, butylated hydroxyanisole and butylated hydroxytoluene;
2) Colecalciferol concentrate, oil form (1 MIU/g) 0.08 mg contains: colecalciferol, DL-α-tocopherol and medium-chain triglycerides;
3) in the form of folic acid hydrate.

Excipients: lactose monohydrate, orange flavor oil 05073, polysorbate 80, glycerol, castor oil, citric acid, sorbitol (E420), dextrose (liquid glucose) (dry substance), magnesium stearate, Capol 600 Pharma, mineral oil, povidone K-25, dimethicone (antifoam 1510) (E900), sucrose.

1 intensely pink tablet additionally contains: dye ponceau 4R (E124), titanium dioxide (E171).
1 yellow tablet additionally contains: dye sunset yellow 06080 (E110), dye quinoline yellow (E104), titanium dioxide (E171).
1 orange tablet additionally contains: dye sunset yellow 06080 (E110), titanium dioxide (E171).
1 green tablet additionally contains: dye indigo carmine (E132), dye quinoline yellow (E104), titanium dioxide (E171).

15 pcs. – blisters (2) – cardboard packs.
15 pcs. – blisters (4) – cardboard packs.

Marketing Authorization Holder

Krka d.d., Novo mesto (Slovenia)

Dosage Form

Bottle OTC Icon Pikovit® Syrup (for children): bottle 150 ml with a dosing spoon

Dosage Form, Packaging, and Composition

Syrup for children in the form of a thick, viscous, opalescent liquid, from light yellow to brownish-orange in color, with a citrus smell; the presence of barely visible inclusions is acceptable.

5 ml
Retinyl palmitate 1.7 MIU/g (900 IU)
Colecalciferol 1 MIU/g (100 IU)
Ascorbic acid 50 mg
Thiamine hydrochloride 1 mg
Riboflavin sodium phosphate 1 mg
Pyridoxine hydrochloride 0.6 mg
Cyanocobalamin 1 mcg
Nicotinamide 5 mg
Dexpanthenol (D-panthenol) 2 mg

Excipients: agar, tragacanth gum, sucrose, liquid dextrose (glucose), orange oil flavor, grapefruit flavor, orange flavor, polysorbate 80 (tween 80), citric acid monohydrate, dye ponceau 4R (E124), sodium benzoate (E211), purified water.

150 ml – dark glass bottles (1) with first-opening control, complete with a dosing spoon – cardboard packs.

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