Plantaglucid (Granules) Instructions for Use

ATC Code

A03 (Drugs for the treatment of functional gastrointestinal disorders)

Active Substance

Plantago major (BP British Pharmacopoeia)

Clinical-Pharmacological Group

Herbal preparation that stimulates the secretory and motor functions of the gastrointestinal tract and bronchi

Pharmacotherapeutic Group

Spasmolytic agent of plant origin

Pharmacological Action

A herbal preparation. It has antiseptic, anti-inflammatory, spasmolytic, enveloping, and expectorant effects, promotes tissue regeneration and activates gastric secretion.

The antiseptic effect (against staphylococci, Pseudomonas aeruginosa, hemolytic streptococcus) is due to the presence of phytoncides.

The anti-inflammatory, wound- and ulcer-healing effects are associated with the presence of polysaccharides, pectin and tannins, benzoic and salicylic acids. Polysaccharides activate interferon formation, zinc and flavonoids contribute to the normalization of phagocytosis. The combination of polysaccharides with enzymes and vitamins promotes the acceleration of regeneration. These effects are also closely related to the ability of plantain to increase the resistance of cells and tissues to oxygen deficiency. The pronounced antihypoxic effect is provided by organic (especially citric) and phenolcarboxylic (ferulic, caffeic, coumaric) acids, flavonoids (derivatives of luteolin, quercetin, apigenin), vitamin C, copper and zinc. The hemostatic effect is associated with the presence of vitamin K.

Plantain regulates digestion, increases appetite, reduces the tone of the smooth muscles of the stomach and intestines, and has an anti-inflammatory and regenerating effect in gastritis, gastroduodenitis and other inflammatory diseases of the gastrointestinal tract. Iridoid glycosides, aucubin, catalpol and bitters included in its composition enhance the secretion of gastric juice and increase the acidity of gastric contents.

Due to mucus, enzymes, and phytoncides, plantain also has an expectorant effect, restoring the protective function of the ciliated epithelium of the respiratory tract.

Saponins, hydroxycinnamic acids, flavonoids and pectin substances contribute to lowering blood cholesterol levels.

Indications

Used as part of combination therapy: for the treatment of gastrointestinal diseases – acute and chronic gastritis, gastric and duodenal ulcers with preserved and reduced secretion, enterocolitis, enzymopathies, dysbiosis; for the treatment of infectious and inflammatory diseases of the respiratory organs, including rhinitis, tonsillopharyngitis, bronchitis, pneumonia, whooping cough.

For external use: dermatitis of various etiologies, wounds, cuts, bruises, trophic ulcers, boils, abscesses, burns.

For local use: gynecological diseases, cervical erosion.

ICD codes

Dosage Regimen

Granules

For the treatment of gastrointestinal diseases, plantain is taken orally as a prepared infusion, 15-50 ml 15-30 minutes before meals. The course of treatment is 1-8 weeks. The juice is taken 1 tablespoon (dissolved in 50 ml of warm water) 15-20 minutes before meals 3-4 times/day for 1 month.

For the treatment of respiratory diseases, plantain is used as an infusion or juice in the same doses but 30 minutes after meals. For colds, juice diluted 5-10 times with warm water can be instilled 2-3 drops into each nostril 3-6 times/day.

For the treatment of dermatological diseases, juice and infusion can be used externally as dressings, lotions or washings, 3-4 times/day, and for burns – regularly, at intervals of 1-1.5 hours.

In gynecological practice, juice is used for douching, sitz baths, instillations, and vaginal tampons.

Adverse Reactions

Rarely: allergic reactions; when taken orally – heartburn.

Contraindications

Hypersensitivity to Plantago major; increased secretion of digestive glands; gastric and duodenal ulcer in the acute phase.

Use in Pregnancy and Lactation

During pregnancy and breastfeeding, it is possible to use according to indications in cases where the intended benefit to the mother outweighs the potential risk to the fetus or infant.

Pediatric Use

It is possible to use in children according to indications, in age-appropriate recommended doses and dosage forms. It is necessary to strictly follow the instructions for Plantago major preparations regarding indications and contraindications for use in children of different ages for specific dosage forms of Plantago major.

Special Precautions

The therapeutic effects of Plantago major are most fully manifested when using the juice.

The prepared infusion is stored in a cool place for no more than 2 days.

Drug Interactions

When treating respiratory diseases, it should not be used simultaneously with antitussive medications, as this makes it difficult to expel liquefied sputum.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.