Salvia officinalis folia (Herbal raw material) Instructions for Use

ATC Code

A01AD11 (Other drugs)

Active Substance

Salvia (BP British Pharmacopoeia)

Clinical-Pharmacological Group

A drug with antimicrobial and anti-inflammatory action for topical use in ENT practice

Pharmacotherapeutic Group

Herbal anti-inflammatory agent

Pharmacological Action

A herbal remedy. It contains essential oils (main components – alpha-thujone, beta-thujone, 1,8-cineole, camphor, borneol, isobutyl acetate, camphene, linalool, alpha- and beta-pinene, viridiflorol, alpha- and beta-caryophyllene); caffeic acid and its derivatives (rosmarinic acid, chlorogenic acid); diterpenes (main components – carnosic acid, rosmanol, saphysinolid); flavonoids (including apigenin- and luteolin-7-glucosides, a number of methylated aglycones, including genkwanin, genkwanin-6-methyl ether; triterpenes (main component – ursolic acid).

Salvia has antibacterial, fungistatic, virostatic, astringent, secretolytic action, and helps to reduce sweating.

Indications

Use as part of combination therapy for the following inflammatory conditions of the oral cavity, pharynx, and larynx:

• Acute and chronic pharyngitis
• Acute and chronic tonsillitis
• Acute and chronic laryngitis
• Gingivitis and periodontal diseases
• Stomatitis and related lesions of the oral mucosa

ICD codes

Dosage Regimen

Prepare an infusion using 10 g of raw material per 200 ml of water.

Use the prepared, cooled infusion for gargling several times a day as required for symptomatic relief.

Herbal raw material

Use the prepared infusion (10 g of raw material per 200 ml of water) for gargling.

Adverse Reactions

Possible adverse reactions include allergic reactions such as skin rash, itching, or urticaria.

Discontinue use immediately and consult a physician if any signs of hypersensitivity appear.

Contraindications

Do not use under the following conditions:

• Hypersensitivity to sage (Salvia officinalis) or any other plants from the Lamiaceae family.
• Patients with a known allergy to any component of the preparation.
• Children under 12 years of age due to the thujone content and lack of safety data in this population.

Drug Interactions

No specific drug interactions are currently known for topical use of sage infusion.

Exercise caution with concomitant use of sedative medications or anticonvulsants due to the theoretical potential for thujone to affect the central nervous system.

Inform your physician about all medications you are taking.

Overdose

Overdose from topical use is unlikely. Accidental ingestion of large quantities of the essential oil or concentrated extract may lead to symptoms of thujone toxicity.

These symptoms may include tachycardia, dizziness, vertigo, tremors, and seizures.

In case of suspected overdose, seek immediate medical attention and provide symptomatic and supportive care.

Use in Pregnancy and Lactation

During pregnancy and breastfeeding, it can be used as indicated after consultation with a doctor, in cases where the intended benefit to the mother outweighs the potential risk to the fetus or infant.

Pediatric Use

Contraindicated for use in children under 12 years of age.

Special Precautions

Store the prepared infusion in a cool place for no more than 2 days.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.