Mastodon

Sennae folia (Tablets, Herbal raw material) Instructions for Use

ATC Code

A06AB06 (Sennosides A and B)

Active Substance

Senna (BP British Pharmacopoeia)

Clinical-Pharmacological Group

Laxative drug that stimulates intestinal peristalsis

Pharmacotherapeutic Group

Laxative of plant origin

Pharmacological Action

A laxative of plant origin. Senna leaves contain dianthrone glycosides (about 3%) – sennosides A, A1, B-G; a small amount of anthraquinone glycosides, including aloe-emodin and rhein 8-glycosides; about 10% mucilage; flavonoids, including kaempferol derivatives; naphthalene glycosides.

It stimulates peristalsis of the large intestine, causing a normal bowel movement 8-10 hours after administration. It acts selectively on the colon, restores normal bowel function, and does not affect digestion.

Indications

Constipation due to hypotension and sluggish peristalsis of the large intestine. Regulating bowel movements in hemorrhoids, proctitis, anal fissures; spastic and atonic constipation of various etiologies.

ICD codes

ICD-10 code Indication
K59.0 Constipation
K60 Fissure and fistula of anus and rectum
K62.8 Other specified diseases of anus and rectum (including proctitis)
K64 Hemorrhoids and perianal venous thrombosis
ICD-11 code Indication
DB32.1 Slow-transit constipation
DB50.Z Fissure or fistula of anal region, unspecified
DB6Z Hemorrhoids or perianal venous diseases, unspecified
DB70.Z Infections of anal and rectal regions, unspecified
DB72.Z Some specified diseases of the anal canal, unspecified
DD91.1 Functional constipation
DE2Z Diseases of the digestive system, unspecified
EG61 Infections of the anus or perianal skin

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Herbal raw material

4 filter bags (6 g) are placed in a glass or enamelware, poured with 200 ml (1 cup) of boiling water, covered with a lid and infused until completely cooled, the filter bags are squeezed out. The volume of the resulting infusion is adjusted to 200 ml with boiled water.

Take orally 1/2 cup at night. The course of treatment is 2-3 weeks. The infusion is recommended to be shaken before use.

Tablets

Take orally in the evening after meals. The dose depends on the dosage form used.

Adverse Reactions

Possible allergic reactions, abdominal pain, flatulence, diarrhea; with long-term use – colitis.

Contraindications

Hypersensitivity to senna; intestinal obstruction, abdominal pain of unclear origin, water-electrolyte imbalance, acute inflammatory diseases of the abdominal organs, proctitis and hemorrhoids in the acute stage, strangulated hernia, gastrointestinal bleeding, uterine bleeding, cystitis, spastic colitis, spastic constipation; pregnancy, breastfeeding period; childhood – depending on the dosage form.

Use in Pregnancy and Lactation

Use is contraindicated during pregnancy and lactation (breastfeeding).

Use in Hepatic Impairment

Use with caution in liver diseases.

Use in Renal Impairment

Use with caution in kidney diseases.

Pediatric Use

Use in children of appropriate age categories is possible strictly according to indications, in recommended doses and dosage forms. It is necessary to strictly follow the instructions in the senna drug leaflets regarding contraindications for the use of specific senna dosage forms in children of different ages.

Special Precautions

With long-term use of senna preparations, habituation may develop, so it is advisable to alternate them with other laxatives.

Drug Interactions

Senna preparations reduce the absorption of tetracycline.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Marketing Authorization Holder

Ivan-Chai JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material 1 pack
Senna leaves 50 g

50 g – cardboard packs.

Marketing Authorization Holder

Ivan-Chai JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

Krasnogorskleksredstva, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material 1 pack
Senna leaves 50 g

50 g – cardboard packs.

Marketing Authorization Holder

Krasnogorskleksredstva, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

Lek S+, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material 1 pack
Senna leaves 50 g

50 g – bags (1) – cardboard packs.

Marketing Authorization Holder

Lek S+, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

Lek S+, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material, crushed: packs 10 g

Dosage Form, Packaging, and Composition

Herbal raw material, crushed 1 pack
Senna leaves 10 g

10 g – cardboard packs with inserted polypropylene bags.

Marketing Authorization Holder

Lek S+, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material: packs 50 g

Dosage Form, Packaging, and Composition

Herbal raw material 1 pack
Senna leaves 50 g

50 g – cardboard packs with inserted paper bags.

Marketing Authorization Holder

Lek S+, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder: filter bags 1.5 g 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

Magnolia SMPF, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material 1 pack
Senna leaves 50 g

50 g – cardboard packs.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material, crushed 1 pack
Senna leaves 50 g

50 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

Microgen NPO, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter-bags 10, 20, 24, 30, or 50 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.
1.5 g – filter bags (24) – cardboard packs.
1.5 g – filter bags (30) – cardboard packs.
1.5 g – filter bags (50) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material crushed 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material, crushed 1 pack
Senna leaves 50 g

50 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material, crushed 25 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material, crushed 1 pack
Senna leaves 25 g

25 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material, crushed 30 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 pack
Senna leaves 30 g

30 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material crushed 75 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 pack
Senna leaves 75 g

75 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Crushed herbal raw material 100 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 pack
Senna leaves 100 g

100 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material, crushed 300 g: paper bags

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 bag
Senna leaves 300 g

300 g – Paper bags.

Marketing Authorization Holder

St.-Medifarm, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material, crushed 500 g: paper bags

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 bag
Senna leaves 500 g

500 g – Paper bags.

Marketing Authorization Holder

Firm "Fito-Bot", LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

Health Firm, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Crushed leaves: packs 30 g, 40 g, 50 g, 60 g, 70 g, 80 g, 90 g, or 100 g

Dosage Form, Packaging, and Composition

Crushed leaves in the form of a mixture of leaf pieces, petioles, stems, petals, sepals, fruit valves, and seeds; color is grayish-green, light green, yellowish-green, or brownish-green with yellow, white, and brown specks; odor is weak; taste of the aqueous extract is slightly bitter, with a sensation of sliminess.

1 pack
Senna leaves 100%

30 g – bags (1) – cardboard packs.
40 g – bags (1) – cardboard packs.
50 g – bags (1) – cardboard packs.
60 g – bags (1) – cardboard packs.
70 g – bags (1) – cardboard packs.
80 g – bags (1) – cardboard packs.
90 g – bags (1) – cardboard packs.
100 g – bags (1) – cardboard packs.

Marketing Authorization Holder

Health Firm, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Leaves crushed: packs 50 g

Dosage Form, Packaging, and Composition

Crushed leaves 1 pack
Senna leaves 50 g

50 g – cardboard packs with an inner bag.

Marketing Authorization Holder

Health Firm, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Leaves powder: filter bags 1.5 g 20 pcs.

Dosage Form, Packaging, and Composition

Leaves powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.

Marketing Authorization Holder

Fito-Bot, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material crushed 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material 1 pack
Senna leaves 50 g

50 g – cardboard packs with paper bags inside.

Marketing Authorization Holder

Fitofarm PKF, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material crushed 50 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 pack
Senna leaves 50 g

50 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

Fitofarm PKF, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material – powder 1.5 g: filter bags 10 or 20 pcs.

Dosage Form, Packaging, and Composition

Herbal raw material – powder 1 filter bag
Senna leaves 1.5 g

1.5 g – filter bags (10) – cardboard packs.
1.5 g – filter bags (20) – cardboard packs.

Marketing Authorization Holder

Fitofarm PKF, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folia Herbal raw material crushed 35 g: packs

Dosage Form, Packaging, and Composition

Herbal raw material crushed 1 pack
Senna leaves 35 g

35 g – Paper bags (1) – cardboard packs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae extract siccum Tablets 300 mg: 10, 20, 30, or 50 pcs.

Dosage Form, Packaging, and Composition

Tablets from brownish-gray to brown with a greenish tint, with darker and lighter specks; round, flat-cylindrical with a bevel and a score.

1 tab.
Dry senna leaf extract 300 mg

Excipients : lactose monohydrate (milk sugar) – 24 mg, potato starch – 64 mg, calcium stearate – 12 mg.

10 pcs. – contour cell packaging (1) – cardboard packs.
10 pcs. – contour cell packaging (2) – cardboard packs.
10 pcs. – contour cell packaging (3) – cardboard packs.
10 pcs. – contour cell packaging (5) – cardboard packs.
10 pcs. – non-cell contour packaging (200) – group packaging (for hospitals).
10 pcs. – non-cell contour packaging (400) – group packaging (for hospitals).
10 pcs. – non-cell contour packaging (500) – group packaging (for hospitals).
10 pcs. – non-cell contour packaging (600) – group packaging (for hospitals).
10 pcs. – non-cell contour packaging (1000) – group packaging (for hospitals).

Marketing Authorization Holder

Pharmtsentr Vilar JSC (Russia)

Dosage Form

Bottle OTC Icon Sennae extract siccum Tablets 300 mg: 10 pcs.

Dosage Form, Packaging, and Composition

Tablets 1 tab.
Dry senna leaf extract 300 mg

10 pcs. – non-cell contour packaging.

Marketing Authorization Holder

Health Firm, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folium briket Raw material – round briquettes 8 g: 6 pcs.

Dosage Form, Packaging, and Composition

Raw material – round briquettes 1 briquette
Senna leaves 8 g

6 pcs. – blisters.

Marketing Authorization Holder

Health Firm, LLC (Russia)

Dosage Form

Bottle OTC Icon Sennae folium briket Raw material – slab (banderole) briquettes 75 g: packs

Dosage Form, Packaging, and Composition

Raw material – slab (banderole) briquettes 1 briquette
Senna leaves 75 g

1 pc. – paper packs.

Table of Contents

→ TABLE OF CONTENTS