Sepia officinalis (Granules) Instructions for Use

Marketing Authorization Holder

Boiron (France)

Contact Information

Boiron (France)

ATC Code

V30 (Not assigned)

Dosage Forms

	Sepia officinalis	Homeopathic granules C5: 4 g tube with granule counter
		Homeopathic granules C9: 4 g tube with granule counter
		Homeopathic granules C15: 4 g tube with granule counter
		Homeopathic granules C30: 4 g tube with granule counter

Dosage Form, Packaging, and Product Composition

Excipients: sucrose, lactose.

4 g – tubes with granule counter (1) – cardboard packs.

Clinical-Pharmacological Group

Single-component homeopathic preparation of animal origin

Pharmacotherapeutic Group

Homeopathic agent

Pharmacological Action

The raw material Sepia officinalis (cuttlefish ink) is extracted from the marine mollusk of the cephalopod class – the cuttlefish. Cuttlefish ink is a thick blackish-brown liquid that the animal abruptly expels to mask its presence in case of danger or when attacking its prey. This liquid has a neutral reaction, a slightly salty taste, and dissolves in water when fresh.

The composition of cuttlefish ink mainly includes

• Amino acids, mainly tyrosine and its derivative DOPA;

• Taurine, a product of cysteine conversion, detected:
  • In free state in tissues and urine;
  • Conjugated with cholic acids in the form of taurocholic acids (sodium taurocholate);

• Cuttlefish melanin, a black pigment, a copolymer of indole-5,6-quinone and 2-carboxyindole-5,6-quinone;

• Various trace elements (Mg, Cu, Si) and mineral salts (in particular, NaCl);

• Enzymes, specifically tyrosinase, which is involved in the metabolism of norepinephrine.

The very rich composition of the substance Sepia officinalis (Sepia officinalis) is directly related to its primary action on diseases of the digestive system, gallbladder disorders, and dermatological, endocrine, and neurophysic disorders.

Indications

Key symptoms for prescribing the drug

• Sensation of emptiness at the level of the epigastric fossa due to gastric ptosis;

• Heaviness in the pelvic area with radiating pain to the lumbosacral region, often associated with uterine prolapse;

• Sensation of a “heavy ball” in the rectum, not subsiding after defecation;

• Similar sensation of a ball in the lower part of the pharynx;

• Hot flashes, often from the pelvic area to the face, with sweating and a feeling of weakness.

Main cases of clinical application

Gastroenterology

• Dyspepsia associated with gastric ptosis, in hypochlorhydria;

• Biliary dyskinesia, accompanied or not by stone formation, expressed by pain in the right hypochondrium, decreasing when lying on the right side, corresponding to gallbladder hypokinesis (gallbladder ptosis or an “hourglass” gallbladder image observed on oral cholecystography);

• Colonopathy with constipation or insufficient intestinal discharge with a sensation of fullness in the rectum, sometimes prolapse;

• Prolapse of hemorrhoids with bleeding from the anus and with pain in the anus, decreasing when walking;

• Migraines, especially on the left side, in people with digestive, genital, behavioral and/or typological symptoms of the drug.

Gynecology, Obstetrics

• Recurrent genital infections with chronic irritating leukorrhea;

• Vaginal mycosis;

• Sensation of “bearing-down pain” (heaviness in the uterus, associated or not with uterine prolapse), forcing to cross legs when sitting;

• Dysmenorrhea, associated with one or more of the previous pathologies, which ultimately leads to decreased libido;

• Menopause with vasomotor disorders having the characteristics of the drug;

• Nausea in the first months of pregnancy, especially in women with a typical “pregnancy mask” or characteristic darkening of the linea alba;

• Tendency to spontaneous miscarriage in the first months of pregnancy or premature birth in women of the sensitive type to the drug.

Urology

• Recurrent urinary system infections without abnormalities in the genitourinary tract requiring surgical intervention.

Pulmonology

• Asthma;

• Chronic bronchitis with greenish-yellow discharge in patients of the sensitive type to the drug.

Dermatology

• Atopic eczema (around the lips or at the elbow fold);

• Fungal eczema, cutaneous mycosis;

• Contact eczema;

• Menstrual labial or genital herpes;

• Acne, especially in the perioral area, varying in intensity depending on the menstrual cycle;

• Psoriasis with fissure formation, bleeding, slightly painful or painless;

• Chloasma.

Behavioral Disorders

• General asthenia with low blood pressure in the sensitive type;

• Reactive depressive states in situations of anxiety or postpartum, characterized by withdrawal into oneself, affective indifference towards others.

Dosage Regimen

Sublingually.

The granules should be dissolved in the mouth 30 min before meals or 60 min after meals.

For children from 0 to 3 years old, the granules are first diluted by shaking in 10-15 ml of water at room temperature and given to drink.

The optimal amount per dose is 5 granules.

Consultation with a doctor is necessary to determine the potency, frequency, and duration of administration.

Adverse Reactions

None described to date.

Contraindications

• Individual sensitivity to the drug;
• Lactose intolerance.

Special Precautions

The dosage regimen and frequency of administration are determined by the doctor.

If there is no therapeutic effect within 3 days, or if adverse reactions occur, a doctor should be consulted.

Overdose

No information on overdose cases has been received to date.

Drug Interactions

When treating with Sepia officinalis, it is possible to use other medications.

Storage Conditions

At a temperature not exceeding 25°C (77°F).

Shelf Life

Shelf life – 5 years.

Dispensing Status

The drug is available without a prescription.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.