Amixin (Tiloron) tablets

The composition and form of issue: 

Tablets, film-coated. 1 tablet contains tiloron 0.06 g

excipients: magnesium carbonate basic PVP calcium stearate Aerosil vaseline oil sugar tropeolin About talc titanium dioxide gelatin beeswax 

in banks polymer of 6 or 10 PCs in the paper cartons 1 Bank.

Tablets, film-coated. 1 tablet contains tiloron 0.125 g

excipients: magnesium carbonate basic PVP calcium stearate Aerosil vaseline oil sugar tropeolin About talc titanium dioxide gelatin beeswax 

in banks polymer of 6 or 10 PCs in the paper cartons 1 Bank.

Description pharmaceutical form:

Tablets, film-coated from light-yellow to yellow, round, biconvex shape. In the cross-section are seen 2 layers. The core of the tablets of orange color.

Pharmacokinetics:

After intake of rapidly absorbed from the gastrointestinal tract. Bioavailability is 60%. The plasma protein binding is about 80%. No biotransformation and accumulation in the body. T1/2 is 48 hours Excreted almost unchanged in the faeces (70%) and urine (9%).

Description pharmacological action:

It stimulates the production of interferons (alpha, beta, gamma) cells of the intestinal epithelium, hepatocytes, T-lymphocytes and granulocytes. After intake of maximum production of interferon is defined in the sequence intestine — liver — blood after 4 -24 h Stimulates stem cells of bone marrow, depending on the dose increases antibody production, reduces the degree of immunosuppression, restores the ratio of T-helper/T – suppressor. Effective against influenza viruses and viruses that cause SARS, hepato – and herpes viruses, etc. The mechanism of antiviral action is associated with inhibition of translation of virus-specific proteins in infected cells, resulting in suppressed reproduction of the virus.

Indications:

Viral hepatitis A, B and C, herpes and cytomegalovirus infection in the complex therapy of infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, avioanele, etc.), urogenital and respiratory chlamydia, treatment and prevention of influenza and ARVI in adults in children older than 7 years treatment of influenza and SARS.

Contraindications:

Hypersensitivity, pregnancy, breast-feeding, age up to 7 years.

Side effects:

Allergic reactions, diarrhoeal phenomenon, intermittent fever.

Drug interactions:

Compatible with antibiotics and traditional means of treatment of viral and bacterial diseases (clinically significant interactions Amixin with these funds is not revealed).

Method of application and dose:

Inside, after eating. Adults for non-specific prevention of viral hepatitis A, influenza and other respiratory — 0,125 1 g once a week for 6 weeks.

Treatment of viral hepatitis A — 1st day 0.125 g 2 times, then on the 0,125 grams a day, course of treatment — 1.25 g (10 table.).

Treatment of acute hepatitis b (including in protracted course), or hepatitis C — 1st and 2nd days to 0,125 grams and then on the 0,125 grams a day. The treatment of acute hepatitis b In 2 g (16 table). acute hepatitis C and protracted course of hepatitis b is 2.5 g (20 table.).

Chronic hepatitis b — the initial phase of treatment (2.5 g — 20 table). the first 2 days by 0,25 g, then on the 0,125 grams a day. The continuation phase: from 1.25 g (10 table.) to 2.5 g (20 table.), 0.125 g per week. Heading dose is between 3.75–5 g, duration of treatment is 3.5–6 months (depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process).

Chronic hepatitis C — the initial phase of treatment (2.5 g — 20 table). the first 2 days by 0,25 g, then on the 0,125 grams a day. The continuation phase: 2.5 g (20 table.), 0.125 g per week. Heading dose is 5 g, duration of treatment — 6 months (depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process).

Treatment of influenza and other ARVI, herpes, cytomegalovirus infection, urogenital and respiratory chlamydiosis — during the first 2 days of illness — 0.125 g, then on the 0,125 grams a day. For the treatment of influenza and other respiratory — 0.75 g, herpes and cytomegalovirus infection — 2.5 g, urogenital and respiratory chlamydia — 1,25 g In the complex therapy neyrovirushnykh infections dose set individually, the course of treatment is 4 weeks.

Children 7 years and older for uncomplicated flu or other respiratory — 0.06 g of 1 times a day (after eating) in the 1st, 2nd and 4th days from the beginning of treatment (a course of treatment 0.18 g — 3 table). Of complications of flu or other sharp respiratory viral diseases the drug is taken in 1, 2, 4 and 6 days from the start of treatment (per treatment 0.24 g — 4 table).

Overdose:

Overdoses Amixin unknown.

Precautions:

Comprehensive therapy neyrovirushnykh infections should be under the supervision of a physician.