Aspirin Express, effervescent pills 500 mg, 12 pcs.

Composition

In 1 tablet for making an effervescent drink contains:

Active ingredients

: Acetylsalicylic acid – 500 mg.

Excipients

Microcrystalline cellulose,

corn starch.

Pharmacological action

Aspirin Express belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and has analgesic, antipyretic and anti-inflammatory effects

Indications

Symptomatic treatment:

• Toothache.
• Sore throat.
• Headache.
• Muscle and joint pain.
• Pain during menstruation. Back pain.
• Mild pain in arthritis.

Elevated body temperature in colds and other infectious and inflammatory diseases (in adults and children over 15 years of age).

Use during pregnancy and lactation

The use of high doses of salicylates in the first trimester of pregnancy is associated with an increased frequency of fetal developmental defects (cleft palate, heart defects). In the second trimester of pregnancy, salicylates can be prescribed only taking into account the risk and benefit assessment. The use of salicylates in the third trimester of pregnancy is contraindicated.

Salicylates and their metabolites pass into breast milk in small amounts.

Accidental intake of salicylates during lactation is not accompanied by the development of adverse reactions in the child and does not require discontinuation of breastfeeding. However, breast-feeding should be discontinued with prolonged use or high-dose administration.

Contraindications

• Asthma caused by taking salicylates or other NSAIDs, combined with nasal polyps.
• Combined use of methotrexate at a dose of 15 mg per week or more.
• Severe liver or kidney dysfunction.
• Hypersensitivity to acetylsalicylic acid and other NSAIDs.
• Erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase).
• Gastrointestinal bleeding.
• Hemorrhagic diatheses.
• Hemophilia, thrombocytopenia.
• Glucose-6-phosphate dehydrogenase deficiency.
• Pregnancy (I and III trimester).
• Breast-feeding period.
• Children’s age (up to 15 years).

Use caution in the following cases::

• With concomitant anticoagulant therapy.
• Gout.
• Peptic ulcer of the stomach and / or duodenum (in the anamnesis).
• Erosive gastritis.
• Tendency to gastrointestinal bleeding.
• Hypoprothrombinemia.
• Hypovitaminosis K.
• Anemia.
• Conditions that predispose to fluid retention in the body (including impaired heart function, arterial hypertension).
• Thyrotoxicosis.

Side effects

 From the central nervous system

Dizziness, tinnitus (usually signs of overdose).

 From the hematopoietic system

Hemorrhagic syndrome, thrombocytopenia.

From the urinary system

When used in high doses — hyperoxaluria and the formation of urinary stones from calcium oxalate, damage to the glomerular apparatus of the kidneys.

Allergic reactions

Skin rash, anaphylactic reactions, bronchospasm, angioedema.

From the gastrointestinal tract

Abdominal pain, nausea, vomiting, obvious (black stools, bloody vomiting) or hidden signs of gastrointestinal bleeding, which can lead to iron deficiency anemia, erosive and ulcerative lesions, including perforation, of the gastrointestinal tract.

Rarely-liver function disorders (increased hepatic transaminases, AST , ALT ).

If such symptoms occur, it is recommended to stop taking the drug and immediately consult your doctor.

Interaction

Increased drug toxicity

Increases the toxicity of methotrexate, the effects of narcotic analgesics, other NSAIDs, oral hypoglycemic drugs, heparin, indirect anticoagulants, thrombolytics and platelet aggregation inhibitors, sulfonamides (including co-trimoxazole ), triiodothyronine, reserpine.

 Reduces the effects of uricosuric drugs

Reduces the effects of uricosuric drugs (benzbromarone, sulfinpyrazone ), antihypertensive agents and diuretics (spironolactone, furosemide).

 Increases the concentration of the following drugs in the blood plasma

Increases the concentration of digoxin, barbiturates and lithium preparations in the blood plasma.

Increases the damaging effect on the mucous membrane of the gastrointestinal tract of drugs

Glucocorticosteroids, alcohol and alcohol-containing drugs increase the damaging effect on the mucous membrane of the gastrointestinal tract, increase the risk of gastrointestinal bleeding.

 Impaired absorption of acetylsalicylic acid

Antacids containing magnesium and / or aluminum hydroxide slow and impair the absorption of acetylsalicylic acid.

How to take, course of administration and dosage

Inside, after eating, after dissolving the tablet in a glass of water.

A single dose is 1-2 effervescent tablets. The maximum single dose is 2 effervescent tablets. The maximum daily dose should not exceed 6 tablets.

The intervals between doses of the drug should be at least 4 hours.

The duration of treatment without consulting a doctor should not exceed 5 days-when prescribed as an analgesic and 3 days – as an antipyretic.

Overdose

Symptoms: CNS arousal, Dizziness, severe headache, decreased hearing acuity, visual impairment, nausea, vomiting, increased breathing.

In the late stage of poisoning: drowsiness, convulsions, anuria, depression of consciousness up to coma, respiratory failure, disorders of water and electrolyte metabolism.

Treatment: You should consult a doctor. Treatment should be carried out in a specialized department. At signs of poisoning-induction of vomiting or gastric lavage, appointment of activated charcoal and laxative.

Special instructions

Concomitant use with other NSAIDs and glucocorticoids is undesirable.5-7 days before surgery, it is necessary to cancel the reception (to reduce bleeding during the operation and in the postoperative period).

The likelihood of developing NSAID gastropathy is reduced when prescribed after meals, using tablets with buffer additives or coated with a special enteric coating. The risk of hemorrhagic complications is considered to be the lowest when used in doses per day.

It should be borne in mind that in predisposed patients, acetylsalicylic acid (even in small doses) reduces the excretion of uric acid from the body and can cause the development of an acute attack of gout.

During long-term therapy, it is recommended to regularly perform a blood test and examine feces for hidden blood. Due to the observed cases of hepatogenic encephalopathy, it is not recommended for the relief of febrile syndrome in children.

Form of production

Tablets are effervescent.

Storage conditions

Store in a dry place protected from light at a temperature below 25°C. Keep out of reach of children. Do not use after the expiration date.

Shelf

life is 3 years.

Active ingredient

Acetylsalicylic acid

Dosage form

soluble tablets

Description

For adults, Children over 15 years of age, Pregnant women only in the second trimester as prescribed by a doctor

Indications

Hangover, Osteoarthritis, Rheumatoid Arthritis, Arthritis, Migraines, Colds

Weight

Weight: 50 gr.