Champix is a medication that relieves nicotine addiction.
Active ingredient: varenicline
Champix developed by Pfizer, pharmaceutical company, is one of the most effective medication to fight smoking.
Uses:
Nicotine addiction.
Description:
Maximum varenicline concentration blood occurs in 3-4 hours after the intake. During treatment, stabile and equal concentration occurs in 4 days. The time of partial ejection is 24 hours.
Varenicline has full absorption and bioavailability properties. Meal does not affect on bioavailability, absorption or pharmacinetics of varenicline.
The medication penetrates through hepatoencephalic barrier. Champix has low connection with plasma proteins of blood.
Directions:
Take orally between meals. Do not chew tablets and take with sufficient amount of water.
Before starting the course, a patient should choose a date when he completely stops smoking. Start taking Champix 1 week prior to that date.
From 1 to 3rd day: take 1 tablet (o.5mg) 1 time a day.
From 2nd to 7th day: take 1 tablet (0.5mg) 2 times a day.
From 8th up to the end of the course: take 1 tablet (1mg) or 2 tablets (0.5mg each) 2 times a day.
Recommended course of treatment is 12 weeks. Those patients, who successfully quitted smoking before 12 weeks were over, may take 1 tablet (1mg) or 2 tablets (0.5 mg each) 2 times a day until 12 weeks are over (if needed).
Those patients, who couldn’t quit smoking and started smoking again after 12-week course, may repeat the course. All factors that impeded quitting should be analyzed before starting the new course.
If side effects have occurred, the dosage may be temporarily decreased.
Side effects:
During the course many of side effects may be caused by the smoking ceccation process itself and not directly caused by varenicline action.
Possible side effects are:
- Mood lability
- Irritation
- Anger
- Anxiety
- Sleeping disorder
- Bradycardia (decrease of heartbeats)
- Hyper appetite
- Weight gain
Warnings:
- Do not take if you are allergic to any of the components
- Do not take if you have sever kidneys disorder
- Do not take if you are pregnant or breast-feeding
- Do not give to children 18 years and under
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