Faspik granules for oral solution 400 mg apricot sachet, 12 pcs.
Manufacturer: Zambon S.p.A., Italy$9.00
Active ingredient: | |
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Dosage form: | |
Indications for use: | Arthrosis and arthritis, Colds, Flu, Migraine, Osteoarthritis, Periarthritis, Rheumatoid arthritis |
Dosage
How to take, course of administration and dosage
The drug is taken orally, during or after a meal. Granules should be dissolved in 50-100 ml of water before use.
Dosage for adults according to the testimony:
The dose for adolescents 12 years of age according to the testimony:
The maximum daily dose of Faspik: for children-40 mg / kg, for adults-1200 mg.
For rheumatoid arthritis, higher doses are recommended, but not more than 2400 mg per day. To overcome the morning stiffness of arthritis, the first dose should be taken immediately after waking up.
Duration of Faspic: as an antipyretic-up to 3 days, analgesic – up to 5 days. In patients with impaired liver, kidney or heart function, the dose of the drug is reduced.
Contraindications
Contraindications
Caution is required in the following cases::
Composition
Composition
Composition
Pharmacological action
Nonsteroidal anti-inflammatory drug (NSAID).
Clinical pharmacology
PharmacodynamicAbuprofen – the Active ingredient of Faspik-is a propionic acid derivative and has analgesic, antipyretic and anti-inflammatory effects due to the indiscriminate blockade of cyclooxygenase 1 and 2 and has an inhibitory effect on prostaglandin synthesis. The analgesic effect is most pronounced in inflammatory pain. The analgesic activity of the drug does not belong to the narcotic type. Like all NSAIDs, Faspik exhibits antiplatelet activity. The analgesic effect when using Faspik (ibuprofen in the form of L-arginine salt) develops 10-45 minutes after ingestion. Pharmacokineticsabsorption: well absorbed from the stomach. When using Faspik, the maximum concentration (Cmax) of ibuprofen in plasma of 26 µg/ml and 56 µg/ml is reached within 15-25 minutes after taking the drug on an empty stomach at a dose of 200 mg and 400 mg, respectively. Distribution: ibuprofen is approximately 99% bound to plasma proteins. It is slowly distributed in the synovial fluid and is removed from it more slowly than from the plasma. Biotransformation: ibuprofen is metabolized in the liver mainly by hydroxylation and carboxylation of the isobutyl group. The metabolites are pharmacologically inactive. Elimination: has two-phase elimination kinetics. The plasma half-life (T-i/g) is 1-2 hours. Up to 90% of the dose can be detected in the urine as metabolites and their conjugates. Less than 1% is excreted unchanged in the urine and, to a lesser extent, in the bile.
Indications
Use during pregnancy and lactation
Faspik is contraindicated in pregnant and breast-feeding women.
Contraindications
Caution is required in the following cases::
Side effects
Long-term use of Faspik in high doses increases the risk of ulceration of the gastrointestinal mucosa, bleeding (gingival, gastrointestinal, hemorrhoidal or uterine) and visual disturbances (optic nerve damage, color vision disorders and the development of scotoma).
Interaction
How to take it, course of administration and dosage
The drug is taken orally, during or after a meal. Granules should be dissolved in 50-100 ml of water before use. Dosages for adults according to indications:
Dosages for adolescents from 12 years of age according to indications:
The maximum daily dose of Faspik: for children-40 mg / kg, for adults-1200 mg. For rheumatoid arthritis, higher doses are recommended, but not more than 2400 mg per day. To overcome the morning stiffness of arthritis, the first dose should be taken immediately after waking up.Duration of Faspic: as an antipyretic-up to 3 days, analgesic – up to 5 days. In patients with impaired liver, kidney or heart function, the dose of the drug is reduced.
Overdose
An overdose of ibuprofen may cause the following symptoms: drowsiness, lethargy, nausea, vomiting, abdominal pain, acute renal failure, metabolic acidosis, tinnitus, headache, depression, low blood pressure, tachycardia, bradycardia, atrial fibrillation, coma, respiratory arrest. After taking too high a dose of Faspik, if no more than an hour has passed, you should do a gastric lavage and take activated charcoal. Further, alkaline drinking, forced diuresis, and symptomatic therapy, including correction of blood pressure and acid-base status, are recommended.
Special instructions
Form of production
Granules for the preparation of a solution for oral administration,400 MGCUS: Apricot packagingedit:12 multi-layer foil bags together with instructions for medical use in a cardboard box.
Storage conditions
Keep out of reach of children at temperatures up to 25 °C.
Shelf
life is 3 years. Do not use after the expiration date indicated on the package.
Active ingredient
Ibuprofen
Dosage form
solution for oral administration
Purpose
Children over 12 years old, For adults
Indications
Cold, Periarthritis, Migraine, Osteoarthritis, Flu, Osteoarthritis and Arthritis, Rheumatoid Arthritis
Weight
Weight: 57 gr.
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