Metronidazole tablets, suppositories, solution

Metronidazole is an antibacterial and antiprotozoal synthetic medication with a large spectrum of action.

Description:

The active ingredient of Metronidazole provides antimicrobial and antiprotozoal effects on:

• Peptococcus niger
• Bacteroides spp., Bacteroides distasonis, Bacteroides thetaiotaomicron, Bacteroides fragilis, Fusobacterium spp., Bacteroides ovatus, Bacteroides vulgatus
• Entamoeba histolytica
• Clostridium spp
• Trichomonas vaginalis
• Eubacterium spp
• Peptostreptococcus spp

Metronidazole together with amoxicillin is highly effective against Helicobacter pylori. The medication causes alcohol sensitizing, increases tumor sensitivity to radiation and stimulates reparative processes.

Uses:

• Infections caused by Bacteroides in abdomen area such as peritonitis and liver abscess; in pelvis area such as endomyometritis, endometritis, infections of fornix vaginae after surgery, Fallopian tube and ovaries abscess, soft tissues and skin infections
• Infections caused by Bacteroides and Clostridium such as sepsis
• Gastritis and duodenum ulcer caused by Helicobacter pylori
• Protozoal infections such as intestinal amebiasis, balantidiasis, abenteric amebiasis, thrichomoniasis (including amoebic liver abscess), Trichomonas vaginitis, giardiasis, dermal leishmaniasis, Trichomonas urethritis
• Infections caused by Bacteroides spp., including В. distasonis, В. fragilis, В. vulgalus В. ovatus, В. Thetaiotaomicron such as joint and bone infections, central nervous system infections (cerebrum abscess and meningitis), pneumonia, bacterial endocarditis, empyema and lung abscess
• Alcoholism
• Pseudomembranous colitis cause by use of antibiotics
• For prophylaxis of post surgery complications in rectal area and colon, gynecological surgeries and appendectomy
• For radiation therapy in oncology as a radiosensitization medication. Suppository metronidazole treats urogenital thrichomoniasis and bacterial vaginitis

Directions:

• To treat thrichomoniasis: take 2 tablets 2 times a day during 10 days. In addition, take 2 suppository metronidazole intravaginal 2 times a day (morning and evening). It is recommended to start using the suppository in the beginning of menstrual cycle avoiding irrigation. If necessary, repeat the treatment in 1 month. Children 2-5 years of age take 250mg a day; 5-10 years of age take 375mg a day; 10 years of age and over take 500mg in 24 hours.
• To treat lambliasis: take 2 tablets 2 times a day during 5-7 days.
• To treat latent amebiasis cyst: take 2 tablets 3 times a day during 5-7 days.
• To treat chronic amebiasis: take dosage of 1.5 g and spread for 3 intakes. Take during 5-10 days
• To treat acute amoebic dysentery: take 2.25 g spread in 3 intakes until the symptoms relieved
• To treat liver abscess (together with tetracyclic antibiotics): take maximum 2.5 g during 3-5 days
• To treat balantidiasis: take 750mg 3 times a day during 5-6 days
• To treat ulcerous stomatitis: take 2 tablets 2 times a day during 5 days.
• To treat chronic alcoholism: take 2 tablets in 24 hours up to 6 months.

Side effects:

• Diarrhea, anorexia, constipation, nausea, glossitis, dry mouth, vomit, metallic taste in mouth, pancreatitis
• Cystitis, dysuria, enuresis, polyuria, candidiasis, urine coloring in red-brown
• Dizziness, coordination of movement disorder, confusion, irritation, depression, hallucinations, excessive excitability
• Hives, fever, rash, dermal hyperemia, stuffiness in nose, arthralgia
• Granulopenia, leukopenia

Metronidazole is an effective anti-parasite medication with antiprotozoal and antibacterial properties.