Nystatin 500000 IU 20 tablets

The composition and form of issue: 

Tablets, film-coated. 1 tablet contains:

nystatin 250000 or 500000 IU

auxiliary substances: milk sugar magnesium carbonate basic, calcium OPMC stearinovokisly potato starch MTS?16 titanium dioxide pigment twin?80 triolein About vaseline oil vanilla 

in banks dark glass or polymer banks 20 PCs the paper cartons 1 Bank.

Suppositories for rectal application. 1 supp. contains:

nystatin 250000 or 500000 IU

excipients: propyl ether peroxybenzoyl acid citric acid cooking oil vaseline witepsol H-15 witepsol W?35 

in a contour acheikova package 5 PCs in a pack 2 packs cardboard.

Vaginal suppositories. 1 supp. contains:

nystatin 250000 or 500000 IU

excipients: propyl ether peroxybenzoyl acid acid citric food witepsol N?15 witepsol W?35 

in a contour acheikova package 5 PCs. in cardboard pack 2 packs.

Ointment 1 g contains:

nystatin 100000 IU

excipients: anhydrous lanolin, vaseline medical 

in tubes of 30 grams in a cardboard bundle 1 tuba.

Description pharmaceutical form:

Tablets, coated light yellow in color, with a greenish tint, with a slight odor of vanillin, in cross section are visible two layers.

Rectal suppositories yellow, torpedo-shaped, with a maximum diameter of 1.2 cm

Vaginal suppositories yellow, torpedo-shaped.

The ointment is yellow or brownish-yellow color.

Feature:

Antibiotic from the group of Polenov, actinomycetes produced by Streptomyces noursei.

Pharmacological action:

By binding to sterols in the fungi cell wall and disrupts its permeability, which leads to the release of major components of cells. Active against yeast-like fungi of the genus Candida, including Candida albicans. There has cumulative properties.

Pharmacokinetics:

Poorly absorbed from the gastrointestinal tract. The bulk of the drug taken orally, is excreted in the feces. The local application through the mucous membranes is not absorbed.

Indications:

Mucosal candidiasis (including vaginal, rectal and lower intestine), skin and internal organs prevention of candidiasis at long treatment by antibacterial means, especially in malnourished and debilitated patients.

Contraindications:

Hypersensitivity, violation of the liver, pancreatitis, ulcers disease stomach and duodenal ulcers, pregnancy.

Side effects:

Nausea, vomiting, diarrhea, sometimes fever, chills. Possible risk of spreading resistant forms of fungi (requires discontinuation of the drug).

Drug interactions:

While the use of nystatin and clotrimazole with the activity of the latter decreases.

Method of application and dose:

Inside, regardless of meals. Adults — 500,000 U 4 -8 times a day. In a generalized candidiasis daily dose increase to 6000000 UNITS. Children at the age from 1 year to 3 years — 250000 IU, 3-4 times a day, over 13 years in the 250000-500000 IU 4 times a day. The course of treatment is 10-14 days. If necessary, the course can be repeated after a week.

Rectal deep into the rectum 1 suppository 2 times a day (morning and evening). The course of treatment is 10-14 days. The duration of treatment and the need for repeated courses is determined by the physician.

Vaginally, after the hygienic procedures for -500000 2 250000 IU twice a day (morning and evening). The course of treatment is 10-14 days.

Locally, ointment are thin layer on the affected areas of the skin and mucous membranes 1-2 times a day for 7-10 days. Can be combined with the reception of the drug inside.

Special instructions:

Fungal diseases of the vagina it is recommended that simultaneous treatment of sexual partner. During treatment avoid sexual contacts.

During menstruation, the treatment should not be interrupted.

Storage conditions:

(away from fire)