SpermActin Forte (Powder) Instructions for Use

Marketing Authorization Holder

Pharmamed, JSC (Russia)

Manufactured By

Sternmaid, GmbH & Co. KG (Germany)

Packaged By

BIOVID, LLC (Russia)

Contact Information

PHARMAMED JSC (Russia)

Dosage Form

SpermActin Forte

Powder: sachets 10 g 15 pcs.

Dosage Form, Packaging, and Product Composition

Powder for oral administration.

Excipients: fructose, mannitol (E421, sweetener), citric acid (E330, preservative), silicon dioxide (E551, emulsifier), natural fruit flavor.

10 g – sachets (15) – cardboard packs.

Therapeutic Category

Dietary supplement for maintaining the function of the reproductive system

Properties

A course of the SpermActin Forte dietary supplement increases the likelihood of natural conception, improves progressive motility and the fertilizing ability of sperm, and reduces both the level of sperm DNA fragmentation and the risk of reproductive losses in the first trimester of pregnancy. SpermActin Forte is recommended by leading specialists in the field of reproduction for natural conception, as well as in preparation for IVF and cryopreservation.

The high level of reliability of the clinical study results for SpermActin Forte is confirmed by the inclusion of the product in the systematic international reviews of evidence-based research in the Cochrane Library.

Advantages of SpermActin Forte

• Increases the likelihood of natural conception by 4 times
• Increases the fertilizing ability of sperm by 53%
• Increases the effectiveness of IVF-ICSI by 26.7%
• Reduces the risk of pregnancy termination by 6 times
• Has a high safety profile confirmed by numerous studies

L-carnitine fumarate

L-carnitine restores cellular metabolism by transporting nutrients into the mitochondria to increase energy potential, which positively affects their maturation and also increases the number of progressively motile sperm. It has indirect antioxidant properties, protecting sperm from free radical damage in the epididymis.

Acetyl-L-carnitine

Acetyl-L-carnitine is an active, metabolized form of L-carnitine, which has greater activity than the precursor L-carnitine. It supports stability and ensures the integrity of cell membranes by acetylating phospholipids, the main structural elements of the cell membrane. Acetyl-L-carnitine exerts its therapeutic effects at the earliest stages of spermatogenesis, where it participates in the packaging of genetic material, reducing the risk of sperm DNA fragmentation.

Alpha-lipoic (thioctic) acid

It eliminates the detrimental effects of free radicals on spermatogenesis. It stabilizes cell membranes, protecting genetic material from destruction, thereby reducing the level of sperm DNA fragmentation. A distinctive feature of alpha-lipoic acid is its ability to activate the body’s own antioxidant system by restoring vitamins E and C, as well as glutathione and coenzyme Q10, which eliminates the need for additional intake of these components.

Scope of Application

Of the SpermActin Forte product

• Reduced motility and fertilizing ability of sperm, including after surgery for varicocele;
• Oligoasthenozoospermia stage III-IV;
• Increased sperm DNA fragmentation
• Preparation for assisted reproductive technologies (IVF, ICSI and others);
• Unsuccessful attempts at assisted reproductive technologies (IVF, ICSI and others) associated with the male factor of infertility;
• Pregnancy loss in the first trimester (spontaneous early miscarriage) due to the male factor of infertility;
• Reduced fertility caused by oxidative stress;
• To improve sperm quality in preparation for donation and cryopreservation.

ICD codes

Dosage Regimen

Take orally, in the morning with a meal, after first dissolving in a glass of water.

Adults are prescribed 1 sachet (10 g of powder) once a day.

The duration of use is 3-6 months.

Contraindications

• Individual intolerance to the components of the complex.

Special Instructions

A dietary supplement. Is not a medicinal product.

Consultation with a doctor is recommended before use.

Caking of the powder may occur during storage; it is recommended to shake the sachet before use.

Dispensing Status

Places of sale are determined by the national legislation of the member states of the Eurasian Economic Union.

Storage Conditions

The complex should be stored out of the reach of children, in a dry place at room temperature.

Shelf Life

Shelf life – 3 years.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.