Streptolaven (Ointment) Instructions for Use

Marketing Authorization Holder

Infamed K, LLC (Russia)

ATC Code

D08AX (Other antiseptics and disinfectants)

Dosage Form

Streptolaven

Ointment for external use 0.5%: tubes 15, 20 or 30 g.

Dosage Form, Packaging, and Composition

Ointment for external use white or white with a slight yellowish tint; the presence of brown particles with a weak specific odor is allowed.

Excipients: polyethylene oxide 400 up to 100 g, proxanol-268 24 g.

500 g – polymer jars.
1 kg – polymer jars.

Clinical-Pharmacological Group

Preparation with antibacterial action and proteolytic activity for external use

Pharmacotherapeutic Group

Antiseptic

Pharmacological Action

The main active ingredient of the ointment is Ultralysin (a collagenolytic enzyme obtained from the culture fluid of Streptomyces Lavendulae). The antiseptic Miramistin included in the ointment provides its bactericidal activity against a wide range of gram-positive and gram-negative microorganisms, including antibiotic-resistant ones. The water-soluble base of the ointment, due to its osmotic activity, effectively removes wound exudate and promotes better penetration of miramistin and ultralysin into the wound.

Indications

• Wounds with abundant purulent discharge (1st phase of the wound process) in acute purulent diseases of soft tissues (panaritium, abscesses, phlegmons, paraproctitis, etc.), diabetic, atherosclerotic gangrene;
• For the removal of necrotic tissues from the surface of postoperative, post-traumatic wounds, trophic ulcers, thermal injuries complicated by the development of purulent processes.

ICD codes

Dosage Regimen

Externally. When treating wounds with abundant purulent discharge, Streptolaven ointment is applied after removal of freely lying necrotic tissues, thorough elimination of all blind purulent leaks and treatment with a 3% hydrogen peroxide solution. A thin layer of ointment is applied to the remaining necrotic tissues, and the entire wound cavity is filled with gauze napkins soaked in Streptolaven ointment. The tampons are changed once a day until the inflammatory process stops, the wound surface is completely cleared of necrotic tissues, and granulations and marginal epithelialization appear in the wound.

The recommended ointment consumption per dressing should not exceed 200 g.

Adverse Reactions

Local reactions rarely – a burning sensation at the application site (goes away on its own within 10-15 seconds and does not require discontinuation of the drug), allergic reactions.

Contraindications

• Individual intolerance to the components of the ointment.

Use in Pregnancy and Lactation

Streptolaven may be prescribed during pregnancy and lactation according to indications, since systemic absorption of the active substance is unlikely with external and local use.

Overdose

There have been no reports of Streptolaven overdose to date.

Drug Interactions

Not described.

Storage Conditions

In a place protected from light, out of reach of children, at a temperature from 8°C (46.4°F) to 15°C (59°F).

Shelf Life

Shelf life – 2 years.

Dispensing Status

Over-the-counter.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.