Vicalin (Tablets) Instructions for Use

Instructions
Dosage forms

ATC Code

A02BX (Other drugs for the treatment of gastric and duodenal ulcers and GERD)

Clinical-Pharmacological Group

A drug with antacid, astringent, anti-inflammatory, and antispasmodic action

Pharmacotherapeutic Group

Intestinal antiseptic and astringent

Pharmacological Action

A combined medicinal product that has an astringent, antacid, laxative, and antispasmodic effect.

Magnesium carbonate and Sodium bicarbonate reduce the acidity of gastric juice and decrease pepsin activity.

Bismuth subnitrate forms a protective film on the gastric mucosa, exerting anti-inflammatory, bactericidal, and reparative effects.

The included Acorus calamus and Khellin have an antispasmodic effect, and Frangula bark has a laxative effect.

Indications

Use this medication for the treatment of the following gastrointestinal conditions, primarily when associated with constipation due to its laxative component.

Gastric and duodenal ulcer disease.
Hyperacid gastritis.

ICD codes

Open the list of ICD codes

ICD-10 code	Indication
K25	Gastric ulcer
K26	Duodenal ulcer
K27	Peptic ulcer
K29	Gastritis and duodenitis

ICD-11 code	Indication
DA42.Z	Gastritis, unspecified
DA51.Z	Duodenitis, unspecified
DA60.Z	Gastric ulcer, unspecified
DA61	Peptic ulcer of unspecified site
DA63.Z	Duodenal ulcer, unspecified
DA7Z	Diseases of stomach or duodenum, unspecified

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Administer tablets orally 0.5-1 hour after meals. The standard treatment course is 1 month.

After a mandatory 1-month break, treatment can be repeated if medically necessary. The exact method of administration is dependent on the specific dosage form of the product used.

Adverse Reactions

Adverse effects are generally infrequent and mild. Monitor for loose stools due to the laxative components.

Be aware of potential allergic reactions to any of the active or inactive ingredients in the formulation.

Contraindications

Do not administer this drug under the following conditions due to the risk of exacerbated symptoms or systemic toxicity.

Hypoacid gastritis, chronic appendicitis, or enterocolitis.
Chronic renal failure.
Hypersensitivity to any component of the drug.
Childhood and adolescence under 18 years of age.

Use in Pregnancy and Lactation

Data on use during pregnancy and lactation (breastfeeding) are not available.

Use in Renal Impairment

Contraindicated in chronic renal failure.

Pediatric Use

The drug is contraindicated for use in children and adolescents under 18 years of age.

Special Precautions

It is necessary to consider the possibility of developing encephalopathy associated with the accumulation of bismuth in the central nervous system with long-term use in high doses.

During treatment with the drug, stools become dark green or black in color.

Drug Interactions

Concomitant use with M-cholinoblockers or histamine H₂-receptor blockers may reduce the therapeutic requirement for this drug.

This medication reduces the absorption of tetracycline antibiotics, potentially compromising their efficacy. Concurrent use with other bismuth-containing products increases the risk of elevated bismuth concentration in the blood.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Vicalin [Avva Rus, JSC (Russia)]
Tablets: 10, 50, or 100 pcs.

Marketing Authorization Holder

Avva Rus, JSC (Russia)

Dosage Form

Vicalin

Tablets: 10, 50, or 100 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Acorus calamus rhizomes	25 mg
Bismuth subnitrate	350 mg
Khellin	5 mg
Frangula bark	25 mg
Magnesium carbonate	400 mg
Sodium bicarbonate	200 mg
Rutoside	5 mg

10 pcs. – non-cell contour packs.
10 pcs. – cell contour packs.
10 pcs. – non-cell contour packs (5) – cardboard packs.
10 pcs. – cell contour packs (5) – cardboard packs.
10 pcs. – cell contour packs (10) – cardboard packs.

Vicalin [Obnovlenie Pfc, JSC (Russia)]
Tablets: 10, 50, 100, or 200 pcs.

Marketing Authorization Holder

Obnovlenie Pfc, JSC (Russia)

Dosage Form

Vicalin

Tablets: 10, 50, 100, or 200 pcs.

Dosage Form, Packaging, and Composition

Tablets	1 tab.
Marsh calamus rhizomes	25 mg
Bismuth subnitrate	350 mg
Khellin	5 mg
Buckthorn bark	25 mg
Magnesium carbonate	400 mg
Sodium bicarbonate	200 mg
Rutoside	5 mg

10 pcs. – non-cell contour packs.
10 pcs. – non-cell contour packs (20) – cardboard packs.
10 pcs. – cell contour packs (aluminum/PVC).
10 pcs. – cell contour packs (PVC/paper).
10 pcs. – cell contour packs (aluminum/PVC) (5) – cardboard packs.
10 pcs. – cell contour packs (PVC/paper) (5) – cardboard packs.
10 pcs. – cell contour packs (aluminum/PVC) (10) – cardboard packs.
10 pcs. – cell contour packs (PVC/paper) (10) – cardboard packs.

Vicalin Avexima [Avexima JSC (Russia)]
Tablets: 10 pcs.

Marketing Authorization Holder

Avexima JSC (Russia)

Manufactured By

Irbit Chemical Pharmaceutical Plant, JSC (Russia)

Dosage Form

Vicalin Avexima

Tablets: 10 pcs.

Dosage Form, Packaging, and Composition

Tablets of light brown color with noticeable inclusions, flat-cylindrical in shape, with a score and a bevel; on the break, light brown in color, uniform or with inclusions.

	1 tab.
Bismuth subnitrate	350 mg
Magnesium carbonate	400 mg
Sodium bicarbonate	200 mg
Khellin	5 mg
Rutoside	5 mg
Acorus calamus rhizomes	25 mg
Frangula bark	25 mg