VitUmnus for skin, hair and nails (Capsules) Instructions for Use

Marketing Authorization Holder

Kron, LLC (Russia)

Manufactured By

VTF, LLC (Russia)

Dosage Form

VitUmnus for skin, hair and nails

Capsules: 60 pcs.

Dosage Form, Packaging, and Product Composition

Capsules weighing 500 mg.

^# in terms of tocopherol equivalent.
¹ % of the recommended daily intake level according to TR TS 022/2011 “Food products in terms of their labeling” (Appendix 2).
² % of the adequate intake level according to “Unified sanitary-epidemiological and hygienic requirements for goods subject to sanitary-epidemiological surveillance (control)” (Appendix 5).
* does not exceed the upper permissible intake level according to “Unified sanitary-epidemiological and hygienic requirements for goods subject to sanitary-epidemiological surveillance (control)”.
Information on the nutritional value of the product is determined by calculation based on the average content of the biologically active substance (BAS) in the product.

Composition L-cystine, L-methionine, gelatin capsule (gelatin, colors (iron oxide yellow, candurin, iron oxide black)), Ascorbic acid, zinc citrate, carrier (microcrystalline cellulose), Alpha-Tocopherol Acetate 50% (DL-Alpha-Tocopherol Acetate, modified starch, maltodextrin, silicon dioxide), Niacinamide, Calcium pantothenate, anti-caking agent (amorphous silicon dioxide), vitamin A acetate 500000 IU/g, Thiamine hydrochloride, carrier (magnesium stearate (magnesium salt of stearic acid)), copper citrate, Pyridoxine hydrochloride, Riboflavin, Folic acid, Biotin, sodium selenite.

vitamin A acetate 500000 IU/g (gelatin, corn starch, sucrose, vitamin A acetate, butylated hydroxytoluene) or vitamin A acetate 500000 IU/g (sucrose, gelatin, starch and aluminum salt of octenyl succinic acid ester, vitamin A acetate, butylated hydroxytoluene, sodium aluminosilicate).

Nutritional value (2 caps.): proteins – 0.2 g, carbohydrates – 0.02 g.
Energy value (2 caps.): 3.74 kJ/0.88 kcal.

15 pcs. – blisters (4) – cardboard packs.

Therapeutic Category

Dietary supplement for improving the condition of hair, skin and nails

Indications

• As a dietary supplement to the diet, it is an additional source of vitamins A, C, E, B1, B2, B3 (PP), B5, B6, B7 (H), B9, zinc, copper, selenium, sulfur-containing amino acids L-cystine and L-methionine.
• Specifically formulated to help compensate for nutritional deficiencies that can negatively affect the health and appearance of the skin, hair, and nails.
• Intended for individuals seeking to support the structural integrity of the skin, promote skin elasticity, and maintain a healthy skin barrier function.
• May be used to support hair strength and vitality, contributing to the reduction of brittleness and improving overall hair condition.
• Aims to support nail health by helping to reduce fragility, splitting, and promoting stronger nail growth.
• The combination of antioxidants (Vitamins C, E, A) helps protect cells from oxidative stress caused by environmental factors.

It is important to understand that this product is not a medicinal drug and is not intended to diagnose, treat, cure, or prevent any disease. The effects are associated with filling the deficit of essential micronutrients.

Contraindications

• Individual intolerance to any of the components of the dietary supplement. A detailed composition is provided in the relevant section.
• Pregnancy and breastfeeding. Due to the high content of certain vitamins, such as Vitamin A, which can have teratogenic effects at high doses, the use of this supplement is contraindicated during pregnancy and lactation unless explicitly recommended by a healthcare professional.
• Patients with severe renal impairment or end-stage renal disease, as impaired excretion can lead to accumulation of vitamins and minerals, potentially causing toxicity.
• Individuals with known hypervitaminosis (A or D) or conditions associated with excessive accumulation of fat-soluble vitamins.
• Patients with Wilson’s disease (a disorder of copper metabolism), as the supplement contains copper.
• Persons with hemochromatosis or other iron overload disorders, as the interaction of certain components like vitamin C with iron metabolism must be considered.
• Children and adolescents under 18 years of age, as the safety and efficacy for this age group have not been established and the dosage is calculated for adult needs.

Before starting the supplement, it is strongly recommended to consult with a physician or pharmacist, especially in the presence of any chronic diseases or when taking other medications.

Dosage Regimen

The standard recommended dosage for adults (individuals 18 years and older) is two capsules per day, taken orally with a meal and a sufficient amount of water.

The capsules should be swallowed whole; they should not be chewed or crushed. Taking the supplement with food can enhance the absorption of fat-soluble vitamins (A, E) and may reduce the potential for gastrointestinal discomfort.

The duration of continuous use should not exceed one to two months. If there is a need for a repeated course, it is advisable to take a break and consult a healthcare specialist. Long-term, continuous use of high-dose vitamin and mineral supplements without medical supervision is not recommended.

Do not exceed the recommended daily dose. Consuming a varied and balanced diet is important to ensure adequate intake of other essential nutrients. The supplement is not a substitute for a healthy diet.

Adverse Reactions

Adverse reactions are generally rare when the product is used at the recommended dosage. However, in cases of individual hypersensitivity or exceeding the recommended intake, the following reactions are possible.

Allergic reactions may occur, including skin rash, itching, urticaria (hives), and erythema (redness of the skin). In rare cases, more severe reactions such as angioedema may develop. If any signs of an allergic reaction appear, discontinue use immediately and seek medical attention.

From the gastrointestinal tract, dyspeptic symptoms are possible, such as nausea, epigastric discomfort, bloating, or diarrhea. These symptoms are often dose-dependent and may be mitigated by taking the capsules with a meal.

Due to the high content of certain B vitamins, a transient bright yellow coloration of the urine may be observed. This is a harmless and expected effect, primarily due to riboflavin (Vitamin B2), and is not a cause for concern.

With long-term use of doses significantly exceeding the recommended intake, especially of fat-soluble vitamins, symptoms of hypervitaminosis may develop. For Vitamin A, this can include headache, dizziness, dry skin, and in severe cases, signs of increased intracranial pressure. If you suspect an overdose, discontinue use and consult a doctor.

Drug Interactions

The components of this dietary supplement may interact with certain medications, potentially altering their effectiveness or increasing the risk of adverse effects.

Vitamin A: Concurrent use with oral retinoids (e.g., isotretinoin, acitretin) is contraindicated due to the risk of additive toxic effects and hypervitaminosis A. Use with caution with other vitamin A-containing products.

Vitamin B6 (Pyridoxine): High doses of pyridoxine can reduce the efficacy of levodopa, which is used in the treatment of Parkinson’s disease. It may also antagonize the effects of phenobarbital and phenytoin (anticonvulsants).

Folic Acid: Folic acid can reduce the plasma concentrations of phenytoin and phenobarbital, potentially leading to a loss of seizure control. It may also interfere with the effects of certain chemotherapeutic agents like methotrexate.

Zinc: Oral zinc supplements can reduce the absorption of tetracycline and fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin), as well as penicillamine. It is recommended to take these medications at least 2 hours before or 4-6 hours after taking the supplement. Long-term, high-dose zinc supplementation can lead to copper deficiency.

Copper: The absorption of copper can be reduced by high doses of zinc, which is a consideration given the product contains both minerals.

Vitamin C (Ascorbic Acid): High doses of vitamin C may interfere with the anticoagulant effect of warfarin, though data is conflicting. It may also increase the absorption of iron from supplements and food.

It is imperative to inform your doctor about all dietary supplements and medications you are taking to avoid potential interactions.

Overdose

In case of accidental intake of a significantly higher than recommended dose (a large number of capsules), symptoms of acute overdose may develop, primarily related to the fat-soluble vitamins and minerals in the composition.

Acute Vitamin A overdose can manifest within hours and may include severe headache, dizziness, blurred vision, nausea, vomiting, drowsiness, and irritability. In severe cases, peeling of the skin may occur days after the overdose.

Chronic overdose (hypervitaminosis) from prolonged intake of high doses can lead to more serious conditions, including liver damage, bone pain, visual disturbances, and increased intracranial pressure (pseudotumor cerebri).

Symptoms of zinc toxicity from acute overdose may include gastric distress, nausea, vomiting, loss of appetite, abdominal cramps, diarrhea, and headaches. Chronic high intake can lead to copper deficiency, resulting in neurological problems and anemia.

In case of suspected overdose, immediately discontinue the supplement and seek medical attention or contact a poison control center. Treatment is primarily symptomatic and supportive. Gastric lavage or administration of activated charcoal may be considered if the overdose is recent. Do not induce vomiting unless instructed by a healthcare professional. Provide the medical personnel with the product packaging or this leaflet for reference.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.