Calcium-Activ (Tablets) Instructions for Use

Marketing Authorization Holder

DIOD Plant of Environmental Technology and Ecopitanie, PJSC (Russia)

Dosage Form

Calcium-Activ

Tablets: 40 or 80 pcs.

Dosage Form, Packaging, and Product Composition

Composition dried amaranth; calcium carbonate; calcium complexone; vitamin D₃.

Total content per 1 tablet: calcium — 50 mg, vitamin D₃ — 50 IU.

Dosage form and packaging
Tablets 0.5 g. 10 tablets in a blister, 4 or 8 blisters in a cardboard pack.

Therapeutic Category

Dietary supplement for strengthening bone tissue and preventing osteoporosis

Scope of Application

Of the Calcium-Activ product

Recommended as a dietary supplement – an additional source of calcium and vitamin D₃.

Indications

Use this product as a dietary supplement to address specific nutrient gaps.

• Use as an additional source of calcium for individuals with a dietary deficiency.
• Use as an additional source of vitamin D₃ for individuals with an unspecified deficiency.
• Use to support bone tissue strength and in the prevention of osteoporosis as part of a balanced diet.

ICD codes

Dosage Regimen

Take orally with meals to improve absorption. For adults and children over 14 years of age, the dosage is 2 tablets twice daily, providing a total daily intake of 200 mg of calcium and 200 IU of vitamin D₃.

Do not exceed the recommended daily dose. Swallow the tablets whole with a full glass of water. The duration of use is not specified; seek advice from a healthcare professional for long-term administration.

Adverse Reactions

Adverse reactions are uncommon and typically mild. Monitor for gastrointestinal disturbances such as constipation, flatulence, nausea, or abdominal pain.

Discontinue use immediately and consult a physician if any signs of an allergic reaction occur, including rash, pruritus, urticaria, or swelling. Hypercalcemia and hypercalciuria are potential risks with excessive intake.

Drug Interactions

Calcium can decrease the absorption of several medications. Take this product at least 2 hours before or 4 hours after taking tetracycline or quinolone antibiotics, bisphosphonates, levothyroxine, or iron supplements.

Exercise caution with thiazide diuretics due to an increased risk of hypercalcemia. Vitamin D can potentiate the effects of cardiac glycosides; monitor for signs of digitalis toxicity. Consult a healthcare provider for a comprehensive interaction assessment.

Contraindications

Do not use under the following conditions.

• Do not use in cases of known hypersensitivity or individual intolerance to any component of the product, including amaranth, calcium carbonate, calcium complexone, or vitamin D₃.
• Do not use in conditions associated with hypercalcemia, such as hyperparathyroidism, bone metastases, or sarcoidosis.
• Do not use in patients with severe renal impairment or a history of nephrolithiasis.

Overdose

In case of accidental ingestion of a significantly large quantity, seek immediate medical attention or contact a Poison Control Center. Symptoms of overdose are primarily related to hypercalcemia and may include nausea, vomiting, loss of appetite, constipation, abdominal pain, muscle weakness, confusion, and polyuria.

Chronic overdose leads to vascular and tissue calcification. Provide supportive care and discontinue the product. Specific treatment for hypercalcemia may be required.

Dispensing Status

Distributed to the public through pharmacy chains and specialized stores, departments of the retail network.

Storage Conditions

Store in a dry, dark place.

Shelf Life

Shelf life – 3 years.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.