Candide B, cream, 15 g

Composition

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of 1 g of cream contains:

Active ingredients: 

Clotrimazole 10 mg

Beclomethasone 250 mcg

Auxiliary substances: 

White Vaseline Jelly

Liquid Paraffin

Cetomoacrogol wax

Benzyl alcohol

Methylparaben

Propylparaben

Bottled hydroxytoluene

Propylene Glycol

Monosubstituted sodium Phosphate

Anhydrous sodium Phosphate

Purified water.

Pharmacological action

Candide-B is a combined drug for external use. Clotrimazole is a derivative of imidazole.

Disrupts the synthesis of ergosterol, which is part of the fungal cell membrane, which causes a change in its properties and leads to cell lysis.

Beclomethasone is a glucocorticoid that has anti-inflammatory, anti-allergic, anti-exudative, and antipruritic effects.

The drug is active against dermatophytes (Trichophyton, Epidermophyton, Microsporum), yeasts and yeast-like fungi (Candida, Torulopsis, Rhodoturola), fungi, and Malassezia furfur, Aspergillus; some strains of gram-positive bacteria (Streptococcus spp., Staphylococcus spp. Corynebacterium minutissimum), gram-negative bacteria (Bacteroides spp., Gardnerella vaginalis), and Trichomonas vaginalis.

Indications

Fungal infections of the skin caused by sensitive microorganisms (including dermatomycosis, epidermophytosis, dermatosis complicated by a secondary infection), especially against the background of eczematous lesions.

Use during pregnancy and lactation

External use of Candida B cream in pregnant women is allowed in cases where the intended benefit to the mother exceeds the risk to the fetus.

In such cases, the use of the drug should be short and limited to small areas of the skin.

It is not known whether the drug penetrates into the mother’s milk, so during breastfeeding, the use of Candide B is possible only for strict indications, and the drug should not be applied to the skin of the breast before feeding.

Contraindications

Hypersensitivity, skin tuberculosis, chickenpox, measles, herpes, vaccination, syphilitic skin rashes.

With caution. Hypersensitivity, skin tuberculosis, chickenpox, herpes, vaccination, syphilitic skin rashes.

Side effects

Side effects are usually mild in nature.

Local allergic reactions are possible — redness of the skin, burning and tingling sensation at the site of application of the drug.

Rarely, as with other corticosteroids, acne-like changes, hypopigmentation, striae, skin atrophy, hypertrichosis, telangiectasia, and secondary skin infections may develop.

How to take, course of administration and dosage

Externally, on pre-washed and dried affected areas of the skin, lightly rubbing, apply a thin layer 2-3 times a day.

– for inguinal epidermophytosis, smooth skin microsporia and candidiasis, the course of treatment is 2 weeks;

– for foot epidermophytosis-4 weeks.

– if necessary, long-term use should be applied less often-every other day.

– in the treatment of chronic diseases, treatment should be continued for some time after all symptoms disappear, in order to avoid relapse of the disease.

Overdose

Symptoms: 

with prolonged use of Beclomethasone on large areas of skin with impaired integrity or with the use of an occlusive dressing, as well as with prolonged use in children, it is possible to develop side effects associated with suppression and insufficiency of the adrenal cortex.

Treatment: 

discontinuation of the drug and, if necessary, symptomatic therapy.

Special instructions

If the first application of Candide B cream develops a hypersensitivity reaction on the skin (itching, burning or redness), you should immediately stop using the drug and consult a doctor.

Long-term therapy should be avoided as much as possible, especially in children, because of possible suppression of adrenal function.

Application to an extensive surface or the use of occlusive dressings can lead to systemic absorption of Beclomethasone.

Avoid contact with the eyes; do not apply to the skin in the eye area and on the mucous membranes.

The development or spread of infection requires discontinuation of the drug and the appointment of antimicrobial therapy.

Bacterial infection is maintained in warm, moist conditions, including occlusive dressings, so the skin should be cleaned before applying the cream.

There are no data on the adverse effects of Candide B cream on the ability to drive vehicles and mechanisms.

Form of production

Cream

Storage conditions

In a dark place, at a temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Beclomethasone, Clotrimazole

Conditions of release from pharmacies

By prescription

Dosage form

cream

Weight

Weight: 25 gr.