Clarithromycin Teva tablets

The composition and form of issue: 

Tablets, film-coated 1 tablet contains:

clarithromycin 250 or 500 mg

excipients: microcrystalline povidone croscarmellose sodium silica colloidal anhydrous magnesium stearate 

the shell: Opadry II white 31F58914 

in blister 10 or 14 PCs., in a pack of cardboard blister 1 (250 mg) or blister 7 or 10 PCs.in a pack of cardboard 1 (10 PCs. 500 mg) or 2 (7 PCs. 500 mg) blister.

Method of application and doses:

Inside. Adults the usual dose is 250 mg 2 times a day for 7 days, if necessary (in severe infections) dose can be increased to 500 mg 2 times a day for a period of up to 14 days. Children over 12 years of age-dosing regimen, as for adults.

Treatment of duodenal ulcer caused by Helicobacter pylori (adult):

Triple therapy regimen (7-14 days): clarithromycin — 500 mg 2 times a day lansoprazole — 30 mg 2 times a day amoxicillin — 1000 mg 2 times a day.

Triple therapy regimen (7 days): clarithromycin — 500 mg 2 times a day lansoprazole — 30 mg 2 times a day metronidazole — 400 mg 2 times a day.

Triple therapy regimen (7 days): clarithromycin — 500 mg 2 times a day omeprazole — 40 mg/day amoxicillin — 1000 mg 2 times a day or metronidazole — 400 mg 2 times a day.

Triple therapy regimen (10 days): clarithromycin — 500 mg 2 times a day, amoxicillin — 100 mg 2 times a day, omeprazole — 20 mg/day.

Scheme of double therapy (14 days): clarithromycin — 500 mg 3 times a day, omeprazole — 40 mg/day (inside).

Dosing with the defeat of kidney function

Usually, dose adjustment is not required, except for patients with severe kidney lesions (Cl creatinine — <30 ml/min), but if necessary, the total daily dose can be reduced by half, i.e. 250 mg/day or 250 mg 2 times a day (in more severe infections).

While taking ritonavir for patients with impaired renal function recommended dose adjustment according to the following scheme:

When Cl creatinine 30-60 ml/min, clarithromycin dose should be reduced by 50% with Cl creatinine less than 30 ml / min — by 75%. In a joint application of clarithromycin and ritonavir should not be applied doses of clarithromycin greater than 1 g/day.