Indications
Indications
Prevention and complex therapy of influenza and acute respiratory viral infections in adults and children over 6 years of age.
Choose your preferred currency
Choose your preferred currency
$63.00
Active ingredient: | |
---|---|
Dosage form: | |
Indications for use: |
Prevention and complex therapy of influenza and acute respiratory viral infections in adults and children over 6 years of age.
Inside,30 minutes before meals. A single dose for adults and children over 6 years of age is 1 capsule.
For treatment purposes:
take one capsule 3 times a day for 4 days.
For prevention purposes:
– in case of direct contact with a patient with influenza and other acute respiratory viral infections, one capsule 3 times a day for 4 days.
– during the epidemic rise in the incidence of influenza and other acute respiratory viral infections, one capsule 1 time a day for 12 days.
Preventive courses, if necessary, are repeated after 3 weeks (until the epidemic situation normalizes).
Hypersensitivity to the components of the drug, pregnancy, children under 6 years of age.
With caution: during breastfeeding, use is possible if the intended benefit to the mother exceeds the potential risk to the child.
Per capsule
Active ingredients:
Alpha-glutamyl-tryptophan sodium (Thymogen® sodium) – 0.5 mg,
Ascorbic acid – 50 mg,
Bendazole hydrochloride ( Dibazole) – 20 mg,
Auxiliary substances:
Lactose monohydrate – 97.8 mg,
Calcium stearate-1.7 mg
Capsule shell composition: Body: titanium dioxide 2%, gelatin up to 100%.
Cap: titanium dioxide 2%, dye sunset yellow 0.2190%, dye azorubin 0.0328%, gelatin up to 100%.
Per capsule
Active ingredients:
Alpha-glutamyl-tryptophan sodium (Thymogen® sodium) – 0.5 mg,
Ascorbic acid – 50 mg,
Bendazole hydrochloride ( Dibazole) – 20 mg,
Auxiliary substances:
Lactose monohydrate – 97.8 mg,
Calcium stearate-1.7 mg
Capsule shell composition: Body: titanium dioxide 2%, gelatin up to 100%.
Cap: titanium dioxide 2%, dye sunset yellow 0.2190%, dye azorubin 0.0328%, gelatin up to 100%.
Pharmacotherapeutic group: immunostimulating agent.
ATX code: L03AX
Pharmacological properties:
Pharmacodynamics: the drug is a means of etiotropic and immunostimulating therapy, has an indirect antiviral effect against pathogens of influenza A and B, as well as other viruses that cause acute respiratory diseases.
In vitro studies, the drug specifically suppresses (inhibits) the reproduction (replication) of the SARS-CoV-2 virus, which is the causative agent of a new coronavirus infection (COVID-19).
The degree of inhibition of the pathogen increases with increasing drug concentration (linearity of the dose-effect relationship is shown).
Reduces the severity of the main clinical symptoms of influenza and acute respiratory viral infections, as well as reduces the duration of the disease and contributes to its uncomplicated course.
Increases the content of secretory immunoglobulin A (slgA) in the nasopharyngeal mucosa – the entrance gate of infection, increasing the local immunoresistance of the body to viral and bacterial respiratory infections.
When used as a prophylactic agent, the drug increases the potential metabolic activity of innate immune cells (neutrophil granulocytes and monocytes), which, in the event of infection, increases their ability to absorb and destroy bacterial and viral agents by enhancing enzymatic (oxidative) activity, synthesizing cationic proteins, and increasing the number of phagocytic cells. At the same time, the initial state of the metabolic activity of innate immune cells, in the absence of infectious agents, does not change, being within normal values.
Bendazole induces the production of endogenous interferon in the body, has an immunomodulatory effect (normalizes the body’s immune response to various infectious agents). Enzymes that are produced by interferon in cells of various organs inhibit viral replication.
Alpha-glutamyl-tryptophan (thymogen) is a synergist of the immunomodulatory action of bendazole, normalizing the T-cell link of immunity.
Ascorbic acid activates the humoral link of immunity, normalizes capillary permeability, thereby reducing inflammation, shows antioxidant properties, neutralizes oxygen radicals that accompany the inflammatory process, and increases the body’s resistance to infection.
Pharmacokinetics: when taken orally, the drug is completely absorbed from the gastrointestinal tract. The bioavailability of bendazole is about 80%, alpha-glutamyl-tryptophan-no more than 15%, ascorbic acid – up to 90%. Metabolites of ascorbic acid and bendazole are excreted in the urine. Alpha-glutamyl-tryptophan under the influence of peptidases is broken down into L-glutamic acid and L-tryptophan, which are used by the body in peptide synthesis.
Prevention and complex therapy of influenza and acute respiratory viral infections in adults and children over 6 years of age.
The drug is contraindicated for use during pregnancy.
During breastfeeding, use is possible if the intended benefit to the mother exceeds the potential risk to the child.
Use in children
Contraindications: children under 6 years of age.
Hypersensitivity to the components of the drug, pregnancy, children under 6 years of age.
With caution: during breastfeeding, use is possible if the intended benefit to the mother exceeds the potential risk to the child.
Allergic reactions, short-term decrease in blood pressure.
The interaction of alpha-glutamyl-tryptophan with drugs was not detected.
Bendazole prevents an increase in total peripheral vascular resistance due to the use of non-selective beta-blockers. Increases the hypotensive (lowering blood pressure) effect of hypotensive and diuretic drugs. Phentolamine enhances the hypotensive effect of bendazole.
Ascorbic acid increases the concentration of tetracycline and benzylpenicillin antibacterial drugs in the blood. Improves intestinal absorption of iron (Fe) preparations. Reduces the effectiveness of heparin and indirect anticoagulants. Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drinks reduce its absorption and assimilation. When used concomitantly with ASA, the urinary excretion of ascorbic acid increases and the excretion of ASA decreases. ASA reduces the absorption of ascorbic acid by about 30%. Ascorbic acid increases the risk of crystalluria when using drugs containing acetylsalicylic acid (ASA) and short-acting sulfonamides, slows down the excretion of acids by the kidneys, increases the excretion of drugs that have an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood. When used concomitantly, it reduces the chronotropic effect of isoprenaline. Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants. Barbiturates and primidone increase the excretion of ascorbic acid in the urine.
Simultaneous use with antiviral drugs and means of symptomatic therapy of influenza and acute respiratory viral infections is possible.
Consult your doctor if you are taking the medications listed in this section or other medications.
Inside,30 minutes before meals. A single dose for adults and children over 6 years of age is 1 capsule.
For treatment purposes:
take one capsule 3 times a day for 4 days.
For prevention purposes:
– in case of direct contact with a patient with influenza and other acute respiratory viral infections, one capsule 3 times a day for 4 days.
– during the epidemic rise in the incidence of influenza and other acute respiratory viral infections, one capsule 1 time a day for 12 days.
Preventive courses, if necessary, are repeated after 3 weeks (until the epidemic situation normalizes).
Symptoms: short-term decrease in blood pressure in patients with vegetative-vascular dystonia, the elderly. Monitoring of kidney function, blood pressure, and blood glucose levels is necessary.
The drug does not affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
At a temperature not exceeding 25 ° C. Keep out of reach of children.
life is 3 years. Do not use after the expiration date indicated on the package.
: Alpha-Glutamyl, Tryptophan, Ascorbic acid, Bendazole
of the capsule
Nursing mothers as prescribed by a doctor, For adults, Children over 6 years of age
Cold, Flu and Cold Prevention, Flu
Weight: 15 gr.
Only logged in customers who have purchased this product may write a review.
Reviews
There are no reviews yet.