Arpeflu pills 100 mg 30 pcs.

Composition

1 tablet contains:

Active ingredient: 

ethyl ether 6-bromo-5-hydroxy-1-methyl-4-dimethylaminomethyl-2-phenylthiomethylindol-3-carboxylic acid hydrochloride monohydrate.

Pharmacological action

Antiviral agent, has an immunomodulatory and anti-influenza effect, specifically suppresses influenza A and B viruses.

It has interferoninducing properties, stimulates humoral and cellular immune responses, phagocytic function of macrophages, and increases the body’s resistance to viral infections. It prevents the development of post-influenza complications, reduces the frequency of exacerbations of chronic diseases, and normalizes immunological parameters.

The antiviral effect is due to the suppression of the fusion of the lipid envelope of the virus with cell membranes when the virus comes into contact with the cell. Therapeutic efficacy in influenza is manifested in a decrease in intoxication and the severity of catarrhal phenomena, shortening of fever periods and the overall duration of the disease. It is classified as low-toxic medicinal products ( LD 50>4 g / kg). It does not have any negative effects on the human body when administered orally at the recommended doses.

Pharmacokinetics

Absorption is fast. Quickly distributed to organs and tissues. TSMACH when taken at a dose of 50 mg – 1.2 hours,100 mg – 1.5 hours is metabolized in the liver. T1 / 2 – 17-21 hours About 40% is excreted unchanged, mainly in the bile (38.9%) and in a small amount by the kidneys (0.12%). During the first day,90% of the administered dose is removed.

Indications

Prevention and treatment in adults and children:

• influenza caused by viruses A and B;
• acute respiratory viral infections (ARVI) (including those complicated by bronchitis, pneumonia);
• secondary immunodeficiency conditions.

Complex therapy of chronic bronchitis, pneumonia and recurrent herpetic infection.

Prevention of postoperative infectious complications and normalization of immune status in adults.

Contraindications

• Children (up to 3 years);
• presence of diseases such as galactose intolerance, lactase deficiency, glucose-galactose malabsorption;
• hypersensitivity to the components of the drug.

Side effects

Allergic reactions.

How to take, course of administration and dosage

Inside, before meals. Single dose: children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg (2 tablets of 100 mg or 4 tablets of 50 mg).

For non-specific prevention

In direct contact with patients with influenza and other acute respiratory viral infections: children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg once a day for 10-14 days.

During the epidemic of influenza and other acute respiratory viral infections, to prevent exacerbations of chronic bronchitis, relapse of herpetic infection: children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 2 times a week for 3 weeks.

Prevention of postoperative complications: children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 2 days before surgery, then on the 2nd and 5th days after surgery.

For treatment purposes

Flu, other acute respiratory infections without complications: children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5 days.

Flu, other acute respiratory infections with the development of complications (bronchitis, pneumonia, etc. ): children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5 days, then a single dose once a week for 4 weeks.

Special instructions

It does not show central neurotropic activity and can be used in medical practice for preventive purposes in practically healthy people of various professions, including those requiring increased attention and coordination of movements (transport drivers, operators, and so on).

Active ingredient

Umifenovir

Dosage form

Tablets

Description

For adults, Children as prescribed by a doctor, Children over 6 years of age

Indications

Shingles, Colds, SARS, Flu, Flu Prevention, Flu and Cold

Prevention Weight

Weight: 22 gr.